Molecular epidemiology and its current clinical use in cancer management (Q37722954)

22 August 2017

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title

Molecular epidemiology and its current clinical use in cancer management (English)

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22 August 2017

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1

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22 August 2017

En Yun Loy

2

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PubMed ID

20359664

22 August 2017

Chee Seng Ku

series ordinal

3

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PubMed ID

20359664

22 August 2017

Kee Seng Chia

series ordinal

4

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22 August 2017

1 April 2010

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Lancet Oncology Commission

22 August 2017

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22 August 2017

11

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22 August 2017

383-390

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22 August 2017

4

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Finishing the euchromatic sequence of the human genome

22 August 2017

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Genomics. New haplotype map may overhaul gene hunting

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

A haplotype map of the human genome

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Finding the missing heritability of complex diseases

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

The HapMap and genome-wide association studies in diagnosis and therapy

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Translating insights from the cancer genome into clinical practice

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Molecular portraits of human breast tumours

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Gene expression profiling predicts clinical outcome of breast cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Gene-expression signatures in breast cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Interpreting and integrating risk factors for patients with primary breast cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Human genetic variation and its contribution to complex traits

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Genome-wide association study identifies novel breast cancer susceptibility loci

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

A common coding variant in CASP8 is associated with breast cancer risk

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Multiple newly identified loci associated with prostate cancer susceptibility

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

A novel prostate cancer susceptibility locus at 19q13

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Multiple loci with different cancer specificities within the 8q24 gene desert

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Polygenes, risk prediction, and targeted prevention of breast cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Quantitative monitoring of gene expression patterns with a complementary DNA microarray

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Light-directed, spatially addressable parallel chemical synthesis

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Enabling personalized cancer medicine through analysis of gene-expression patterns

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Rethinking screening for breast cancer and prostate cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Genomewide association studies and human disease

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Common genetic variation and human traits

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Genetic risk prediction--are we there yet?

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Familial concordance in cancer survival: a Swedish population-based study.

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Is genetic background important in lung cancer survival?

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Is breast cancer prognosis inherited?

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Allelic diversity in the host genetic background may be an important determinant in tumor metastatic dissemination

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

A five-gene molecular grade index and HOXB13:IL17BR are complementary prognostic factors in early stage breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

CYP2D6 polymorphisms and the impact on tamoxifen therapy

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

PARP inhibitors: will the new class of drugs match the hype?

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Inherited variation in the androgen pathway is associated with the efficacy of androgen-deprivation therapy in men with prostate cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Genomic approaches to outcome prediction in prostate cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Critical review of microarray-based prognostic tests and trials in breast cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Loss of epigenetic control of synuclein-gamma gene as a molecular indicator of metastasis in a wide range of human cancers

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Gene-Expression Profiles and Breast-Cancer Prognosis

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Molecular classification of tamoxifen-resistant breast carcinomas by gene expression profiling

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Clinical and therapeutic perspectives of gene expression profiling for breast cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Neoadjuvant docetaxel before radical prostatectomy in patients with high-risk localized prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Molecular determinants of resistance to antiandrogen therapy

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Genomic strategy for targeting therapy in castration-resistant prostate cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Microarray-based gene expression profiling as a clinical tool for breast cancer management: are we there yet?

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Predicting prostate cancer behavior using transcript profiles

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Adjuvant chemotherapy in oestrogen-receptor-poor breast cancer: patient-level meta-analysis of randomised trials

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Quo vadis with targeted drugs in the 21st century?

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

The cancer biomarker problem

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Evaluating the efficiency of targeted designs for randomized clinical trials

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Gene silencing in cancer in association with promoter hypermethylation

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Epigenetic inactivation of the HOXA gene cluster in breast cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas.

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

Inheritance of a Cancer-AssociatedMLH1Germ-Line Epimutation

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https://api.crossref.org/works/10.1016%2FS1470-2045%2810%2970005-X

7 January 2021

10.1016/S1470-2045(10)70005-X

Identifiers

DOI

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22 August 2017

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PubMed ID

20359664