Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression. (Q37712330)

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6 January 2020

title

Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression (English)

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6 January 2020

author

Kairbaan Hodivala-Dilke

7

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6 January 2020

Daniel Metzger

8

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6 January 2020

Seth G. Grant

10

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6 January 2020

Margaret Frame

11

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6 January 2020

9

Pierre Chambon

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6 January 2020

3

Bryan Serrels

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6 January 2020

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Gordon W McLean

1

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6 January 2020

Noboru H Komiyama

2

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6 January 2020

Hidefumi Asano

4

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6 January 2020

Louise Reynolds

5

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6 January 2020

Francesco Conti

6

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6 January 2020

publication date

1 December 2004

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6 January 2020

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6 January 2020

volume

18

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6 January 2020

issue

24

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6 January 2020

page(s)

2998-3003

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Focal adhesion kinase as a potential target in oncology

6 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535910

The focal adhesion kinase--a regulator of cell migration and invasion

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535910

Biochemical signals and biological responses elicited by the focal adhesion kinase

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535910

Adhesion-linked kinases in cancer; emphasis on src, focal adhesion kinase and PI 3-kinase

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535910

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535910

Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

23 August 2017

1 reference

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Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation

23 August 2017

1 reference

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Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

23 August 2017

1 reference

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Comparison of immunohistochemistry for activated caspase-3 and cleaved cytokeratin 18 with the TUNEL method for quantification of apoptosis in histological sections of PC-3 subcutaneous xenografts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535910

The role of growth factors in mouse skin tumor promotion and premalignant progression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535910

Focal adhesion kinase: at the crossroads of signal transduction.

28 September 2017

1 reference

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Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535910

Elevated expression and point mutation of the Ha-ras proto-oncogene in mouse skin tumors promoted by benzoyl peroxide and other promoting agents

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535910

Decreased focal adhesion kinase suppresses papilloma formation during experimental mouse skin carcinogenesis.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535910

Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis

1 September 2018

1 reference

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Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.

1 September 2018

1 reference

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Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535910

Tumor promotion by abrasion induced epidermal hyperplasia in the skin of mice

1 September 2018

1 reference

12 December 2020

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors

1 reference

12 December 2020

Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells

1 reference

12 December 2020

Caspase activation during spontaneous and radiation-induced apoptosis in the murine intestine

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.316304

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15601818%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15601818%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference