Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma (Q37711887)

22 August 2017

Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma (English)

1 reference

22 August 2017

1 reference

4

1 reference

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9 June 2020

Ulla Mandel

5

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9 June 2020

Thomas Daugbjerg Madsen

8

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9 June 2020

Alexandria P. Cogdill

11

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9 June 2020

22

Carl H June

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9 June 2020

1

Avery D Posey

1 reference

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9 June 2020

author name string

Robert D Schwab

2

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9 June 2020

Alina C Boesteanu

3

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9 June 2020

Boris Engels

6

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9 June 2020

Jennifer D Stone

7

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9 June 2020

Karin Schreiber

9

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9 June 2020

Kathleen M Haines

10

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9 June 2020

Taylor J Chen

12

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9 June 2020

Decheng Song

13

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9 June 2020

John Scholler

14

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9 June 2020

David M Kranz

15

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9 June 2020

Michael D Feldman

16

1 reference

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9 June 2020

Regina Young

17

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9 June 2020

Brian Keith

18

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9 June 2020

Hans Schreiber

19

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9 June 2020

Henrik Clausen

20

1 reference

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9 June 2020

Laura A Johnson

21

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9 June 2020

language of work or name

English

0 references

publication date

1 June 2016

1 reference

22 August 2017

1 reference

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9 June 2020

volume

44

1 reference

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9 June 2020

issue

6

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9 June 2020

page(s)

1444-1454

1 reference

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Chimeric antigen receptor T cells for sustained remissions in leukemia

9 June 2020

cites work

1 reference

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Immature truncated O-glycophenotype of cancer directly induces oncogenic features

23 August 2017

1 reference

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Glycan elongation beyond the mucin associated Tn antigen protects tumor cells from immune-mediated killing

23 August 2017

1 reference

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Initiation of GalNAc-type O-glycosylation in the endoplasmic reticulum promotes cancer cell invasiveness.

23 August 2017

1 reference

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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

23 August 2017

1 reference

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CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia

23 August 2017

1 reference

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Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: clinical evaluation and management of on-target toxicity

23 August 2017

1 reference

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Epigenetic silencing of the chaperone Cosmc in human leukocytes expressing tn antigen

23 August 2017

1 reference

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Deciphering Structural Elements of Mucin Glycoprotein Recognition

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

A novel fluorescent assay for T-synthase activity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Tumour-associated carbohydrate antigens in breast cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

23 August 2017

1 reference

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Altered expression of glycan genes in cancers induced by epigenetic silencing and tumor hypoxia: clues in the ongoing search for new tumor markers.

23 August 2017

1 reference

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Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: a chemotherapy dose-ranging factorial study of safety and immune activation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Mucin-type O-glycosylation and its potential use in drug and vaccine development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Glycosylation in cellular mechanisms of health and disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Colon carcinogenesis in inflammatory bowel disease: applying molecular genetics to clinical practice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Adoptive cellular therapy: a race to the finish line.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Regulatory circuits mediated by lectin-glycan interactions in autoimmunity and cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Importance of MUC1 and spontaneous mouse tumor models for understanding the immunobiology of human adenocarcinomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer

14 September 2017

1 reference

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A mutant chaperone converts a wild-type protein into a tumor-specific antigen

14 September 2017

1 reference

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Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.

14 September 2017

1 reference

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Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia.

14 September 2017

1 reference

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The polymorphic epithelial mucin: potential as an immunogen for a cancer vaccine

14 September 2017

1 reference

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Cancer biomarkers defined by autoantibody signatures to aberrant O-glycopeptide epitopes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Transduction of a novel HLA-DRB1*04:05-restricted, WT1-specific TCR gene into human CD4+ T cells confers killing activity against human leukemia cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Cancer specific Mucin-1 glycoforms are expressed on multiple myeloma.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

ST6GalNAcII mediates the invasive properties of breast carcinoma through PI3K/Akt/NF-κB signaling pathway

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Reciprocal relationship of Tn/NF-κB and sTn as an indicator of the prognosis of oral squamous cell carcinoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Protein glycosylation: chaperone mutation in Tn syndrome

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Purification, characterization, and subunit structure of rat core 1 Beta1,3-galactosyltransferase

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Sialyl Tn antigen is an independent predictor of outcome in patients with gastric cancer.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Expression of Mucin-1 in multiple myeloma and its precursors: correlation with glycosylation and subcellular localization

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5358667

Expression of Tn and sialyl-Tn antigens in endometrial cancer: its relationship with tumor-produced cyclooxygenase-2, tumor-infiltrated lymphocytes and patient prognosis

3 December 2018

1 reference

12 December 2020

Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat

1 reference

12 December 2020

Expression of aberrantly glycosylated Mucin-1 in ovarian cancer

1 reference

12 December 2020

CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes

1 reference

12 December 2020

T and Tn, general carcinoma autoantigens

1 reference

12 December 2020

10.1016/J.IMMUNI.2016.05.014

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27332733%20AND%20SRC:MED&resulttype=core&format=json

release_pxlllb2scngmljs2fcr545ezsy

9 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pxlllb2scngmljs2fcr545ezsy

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27332733%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference