In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing. (Q37710952)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24361318%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing (English)

1 reference

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3 March 2020

0 references

1 reference

1

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3 March 2020

Gregory Wojtkiewicz

8

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3 March 2020

Filip K Swirski

17

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Ralph Weissleder

18

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3 March 2020

19

Matthias Nahrendorf

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3 March 2020

4

Yoshiko Iwamoto

1 reference

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3 March 2020

15

Daniel G Anderson

1 reference

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3 March 2020

Tatiana I Novobrantseva

12

object named as

Tatiana Novobrantseva

1 reference

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3 March 2020

2

Timo Heidt

1 reference

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3 March 2020

7

Benoit Tricot

1 reference

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3 March 2020

10

Hendrik B Sager

1 reference

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3 March 2020

11

Anna Borodovsky

1 reference

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3 March 2020

3

Matthew Sebas

1 reference

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3 March 2020

6

Jessica Truelove

1 reference

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3 March 2020

16

Peter Libby

1 reference

3 March 2020

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Derrick Jeon

5

1 reference

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3 March 2020

Partha Dutta

9

1 reference

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3 March 2020

Boris Klebanov

13

1 reference

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3 March 2020

Kevin Fitzgerald

14

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3 March 2020

language of work or name

English

0 references

publication date

18 December 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24361318%20AND%20SRC:MED&resulttype=core&format=json

Journal of the American College of Cardiology

3 March 2020

published in

1 reference

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3 March 2020

volume

63

1 reference

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3 March 2020

issue

15

1 reference

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3 March 2020

page(s)

1556-1566

1 reference

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Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.

3 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Monocytes from Irf5-/- mice have an intrinsic defect in their response to pristane-induced lupus

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Irf5-deficient mice are protected from pristane-induced lupus via increased Th2 cytokines and altered IgG class switching

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Progress toward in vivo use of siRNAs-II

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Perspectives and opportunities for nanomedicine in the management of atherosclerosis.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Therapeutic siRNA silencing in inflammatory monocytes in mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Macrophages in the pathogenesis of atherosclerosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Extracellular matrix roles during cardiac repair.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Monocytes: protagonists of infarct inflammation and repair after myocardial infarction

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

CCR5 signaling suppresses inflammation and reduces adverse remodeling of the infarcted heart, mediating recruitment of regulatory T cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Development of monocytes, macrophages, and dendritic cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Classically and alternatively activated macrophages contribute to tissue remodelling after myocardial infarction.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Knocking down barriers: advances in siRNA delivery

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Post-infarct remodelling: contribution of wound healing and inflammation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Macrophage roles following myocardial infarction

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Chemical modification: the key to clinical application of RNA interference?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Monocyte and macrophage heterogeneity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Inflammation in atherosclerosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

The inflammatory response in myocardial infarction

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

23 August 2017

Cutaneous wound healing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Macrophage plasticity and polarization in tissue repair and remodelling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Attacking the genome: emerging siRNA nanocarriers from concept to clinic

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Macrophage polarization and plasticity in health and disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Interferon regulatory factor 5 is critical for the development of lupus in MRL/lpr mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992176

Association of interferon regulatory factor 5 haplotypes, similar to that found in systemic lupus erythematosus, in a large subgroup of patients with rheumatoid arthritis

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24361318

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interleukin-1beta and tumor necrosis factor-alpha decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24361318

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impact of heterogeneity of human peripheral blood monocyte subsets on myocardial salvage in patients with primary acute myocardial infarction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24361318

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JACC.2013.11.023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24361318%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24361318%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

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