Mesenchymal stem cells as therapeutic tools and gene carriers in liver fibrosis and hepatocellular carcinoma. (Q37707034)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20220785%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

review article

1 reference

title

Mesenchymal stem cells as therapeutic tools and gene carriers in liver fibrosis and hepatocellular carcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20220785%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

main subject

mesenchymal stem cell

1 reference

1

1 reference

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19 January 2020

Marcela Bolontrade

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20220785%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

M G García

3

1 reference

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19 January 2020

O L Podhajcer

4

1 reference

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19 January 2020

G Mazzolini

5

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19 January 2020

publication date

11 March 2010

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19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20220785%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

17

1 reference

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19 January 2020

issue

6

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19 January 2020

page(s)

692-708

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https://scigraph.springernature.com/pub.10.1038/gt.2010.10

19 January 2020

exact match

0 references

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Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms.

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Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase

21 January 2018

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The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.

21 January 2018

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Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

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Stem cells in liver regeneration, fibrosis and cancer: the good, the bad and the ugly

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Stem cells and liver regeneration.

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A model of liver regeneration

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The role of hepatocytes and oval cells in liver regeneration and repopulation

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Hepatic non-parenchymal cells and extracellular matrix participate in oval cell-mediated liver regeneration

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Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers

21 January 2018

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Endothelial progenitor cells contribute to accelerated liver regeneration.

21 January 2018

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What is the real contribution of extrahepatic cells to liver regeneration?

21 January 2018

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Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

21 January 2018

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Extent of liver resection modulates the activation of transcription factors and the production of cytokines involved in liver regeneration

21 January 2018

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Survivin is upregulated during liver regeneration in rats and humans and is associated with hepatocyte proliferation.

21 January 2018

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Enhanced liver regeneration following changes induced by hepatocyte-specific genetic ablation of integrin-linked kinase.

21 January 2018

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Topical transplantation of mesenchymal stem cells accelerates gastric ulcer healing in rats

21 January 2018

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Immunomodulation of activated hepatic stellate cells by mesenchymal stem cells

21 January 2018

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Mesenchymal stem cell-derived molecules directly modulate hepatocellular death and regeneration in vitro and in vivo

21 January 2018

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21 January 2018

1 reference

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Interferon-gamma exacerbates liver damage, the hepatic progenitor cell response and fibrosis in a mouse model of chronic liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Liver fibrosis -- from bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Commitment of bone marrow cells to hepatic stellate cells in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Hematopoietic origin of hepatic stellate cells in the adult liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Hepatic stellate cells: unique characteristics in cell biology and phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Gene expression profiles during hepatic stellate cell activation in culture and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

How can transforming growth factor beta be targeted usefully to combat liver fibrosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Effect of IL-10 on the expression of HSC growth factors in hepatic fibrosis rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Interleukin-8 and hIRH (SDF1-alpha/PBSF) mRNA expression and histological activity index in patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Capillary endothelial thrombomodulin expression and fibrin deposition in rats with continuous and bolus lipopolysaccharide administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Migration of Bone Marrow and Cord Blood Mesenchymal Stem Cells In Vitro Is Regulated by Stromal-Derived Factor-1-CXCR4 and Hepatocyte Growth Factor-c-met Axes and Involves Matrix Metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Evidence that very small embryonic-like stem cells are mobilized into peripheral blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Hepatocyte growth factor plays roles in the induction and autocrine maintenance of bone marrow stromal cell IL-11, SDF-1 alpha, and stem cell factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Toll-like receptor signaling in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Toll-like receptors on human mesenchymal stem cells drive their migration and immunomodulating responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

The bone marrow functionally contributes to liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Adenovirus-mediated inhibition of SPARC attenuates liver fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Molecular profile of mouse stromal mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

The profile of gene expression of human marrow mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

RNA interference targeting the platelet-derived growth factor receptor beta subunit ameliorates experimental hepatic fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Characterization of TGF-beta 1-binding proteins in human bone marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Smad3-dependent nuclear translocation of beta-catenin is required for TGF-beta1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Therapeutic potential of bone marrow-derived mesenchymal stem cells on experimental liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Bone marrow-derived mesenchymal stem cells protect against experimental liver fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Systemic infusion of FLK1(+) mesenchymal stem cells ameliorate carbon tetrachloride-induced liver fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Therapeutic effect of transplanting HGF-treated bone marrow mesenchymal cells into CCl4-injured rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Human marrow stromal cell therapy for stroke in rat: neurotrophins and functional recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Hepatocyte growth factor gene therapy of liver cirrhosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Hepatocyte growth factor suppresses profibrogenic signal transduction via nuclear export of Smad3 with galectin-7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Hepatic stellate cells express the low affinity nerve growth factor receptor p75 and undergo apoptosis in response to nerve growth factor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Secretion of fibrinolytic enzymes facilitates human mesenchymal stem cell invasion into fibrin clots.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Activation of hepatic stellate cells after phagocytosis of lymphocytes: A novel pathway of fibrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Biochemical heterogeneity of mesenchymal stem cell populations: clues to their therapeutic efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Hedgehog-mediated paracrine interaction between hepatic stellate cells and marrow-derived mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Hepatic stellate cells modulate the differentiation of bone marrow mesenchymal stem cells into hepatocyte-like cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Direct cell contact influences bone marrow mesenchymal stem cell fate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Osteopontin expression is required for myofibroblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Receptor-ligand interaction between CD44 and osteopontin (Eta-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Hypoxic osteocytes recruit human MSCs through an OPN/CD44-mediated pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Transplantation of urokinase-type plasminogen activator gene-modified bone marrow-derived liver stem cells reduces liver fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Isolation, characterization, and transplantation of bone marrow-derived hepatocyte stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Transplantation of bone marrow-derived hepatocyte stem cells transduced with adenovirus-mediated IL-10 gene reverses liver fibrosis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Prophylaxis against carcinogenesis in three kinds of unestablished tumor models via IL12-gene-engineered MSCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Global cancer statistics, 2002

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

21 January 2018

Hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Molecular targeted therapies in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

A subset of human rapidly self-renewing marrow stromal cells preferentially engraft in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Mesenchymal stem cell targeting of microscopic tumors and tumor stroma development monitored by noninvasive in vivo positron emission tomography imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Cirrhosis: new research provides a basis for rational and targeted treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Resolving fibrosis in the diseased liver: translating the scientific promise to the clinic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Gene therapy of liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Expression patterns of PDGF-A, -B, -C and -D and the PDGF-receptors alpha and beta in activated rat hepatic stellate cells (HSC)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Stem cell mobilization and collection in patients with liver cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

BMP-7 functions as a novel hormone to facilitate liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Exogenous mesenchymal stem cells localize to the kidney by means of CD44 following acute tubular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Mesenchymal Stem Cells: Potential Precursors for Tumor Stroma and Targeted-Delivery Vehicles for Anticancer Agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

Nonhematopoietic/endothelial SSEA-1+ cells define the most primitive progenitors in the adult murine bone marrow mesenchymal compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Bone marrow transdifferentiation in brain after transplantation: a retrospective study

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Multipotent mesenchymal stem cells from adult human synovial membrane

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Isolation of multipotent mesenchymal stem cells from umbilical cord blood

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Alveolar bone marrow as a cell source for regenerative medicine: differences between alveolar and iliac bone marrow stromal cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: engraftment and hepatocyte differentiation versus profibrogenic potential

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

HLA expression and immunologic propertiesof differentiated and undifferentiated mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Femoral intra-arterial injection: a tool to deliver and assess recombinant AAV constructs in rodents whole hind limb

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Human bone marrow-derived mesenchymal (stromal) progenitor cells (MPCs) cannot be recovered from peripheral blood progenitor cell collections

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Adult bone marrow is a rich source of human mesenchymal ‘stem’ cells but umbilical cord and mobilized adult blood are not

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Local irradiation not only induces homing of human mesenchymal stem cells at exposed sites but promotes their widespread engraftment to multiple organs: a study of their quantitative distribution after irradiation damage

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Endothelial cell intracellular Ca2+ concentration is increased upon breast tumor cell contact and mediates tumor cell transendothelial migration

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Gastric cancer originating from bone marrow-derived cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

CD133+ hepatic stellate cells are progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Preoperative granulocyte-colony stimulating factor (G-CSF) treatment improves congested liver regeneration

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Sca-1+ endothelial cells (SPECs) reside in the portal area of the liver and contribute to rapid recovery from acute liver disease

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Human biliary epithelial cells secrete and respond to cytokines and hepatocyte growth factors in vitro: interleukin-6, hepatocyte growth factor and epidermal growth factor promote DNA synthesis in vitro

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Extracellular matrix remodeling at the early stages of liver regeneration in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Expression and activation of pro-MMP-2 and pro-MMP-9 during rat liver regeneration

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

https://api.crossref.org/works/10.1038%2FGT.2010.10

1 reference

7 January 2021

Comprehensive analysis of chemotactic factors for bone marrow mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Hepatocyte growth factor promotes remodeling of murine liver fibrosis, accelerating recruitment of bone marrow-derived cells into the liver

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Growth inhibition of colorectal carcinoma by lentiviral TRAIL-transgenic human mesenchymal stem cells requires their substantial intratumoral presence.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Roles of TGF-beta in hepatic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1 alpha

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Bone marrow stromal cells control the growth of hepatic stellate cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Interferon and prevention of hepatocellular carcinoma in viral cirrhosis: an evidence-based approach

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Distribution of mesenchymal stem cells in the area of tissue inflammation after transplantation of the cell material via different routes

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.10

7 January 2021

Identifiers

DOI

10.1038/GT.2010.10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20220785%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference