Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells. (Q37691228)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24207099%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells (English)

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29 February 2020

2

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29 February 2020

Richa Garva

4

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29 February 2020

Constantinos Demonacos

6

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29 February 2020

author name string

Travis Leung

1

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29 February 2020

Subir Singh

3

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29 February 2020

Marija Krstic-Demonacos

5

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29 February 2020

publication date

8 November 2013

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29 February 2020

published in

Breast Cancer Research

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29 February 2020

volume

15

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29 February 2020

issue

6

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29 February 2020

page(s)

R107

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https://scigraph.springernature.com/pub.10.1186/bcr3574

29 February 2020

exact match

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Endoplasmic reticulum stress stimulates p53 expression through NF-κB activation

23 August 2017

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The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies

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Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate.

23 August 2017

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Alcohol promotes breast cancer cell invasion by regulating the Nm23-ITGA5 pathway

23 August 2017

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The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases the sensitivity to taxane in breast cancer cells

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Autophagy regulation by p53.

23 August 2017

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Nrf2 and antioxidant defense against CYP2E1 toxicity

23 August 2017

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Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

23 August 2017

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23 August 2017

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23 August 2017

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Reactive oxygen species in tumor metastasis

23 August 2017

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ROS and p53: a versatile partnership

23 August 2017

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CYP2E1 and oxidative liver injury by alcohol

23 August 2017

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Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?

23 August 2017

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Coping with stress: multiple ways to activate p53.

23 August 2017

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TIGAR, a p53-inducible regulator of glycolysis and apoptosis

23 August 2017

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p53 regulates mitochondrial respiration

23 August 2017

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p53 and breast cancer, an update

23 August 2017

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Cytochrome P450s and other enzymes in drug metabolism and toxicity

23 August 2017

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Association of CYP2E1 gene polymorphism with predisposition to cancer development.

23 August 2017

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The antioxidant function of the p53 tumor suppressor

23 August 2017

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CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes

23 August 2017

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Microtubule-associated protein tau: a marker of paclitaxel sensitivity in breast cancer

23 August 2017

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Cytochrome P450: nature's most versatile biological catalyst

23 August 2017

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Glycolytic enzymes can modulate cellular life span

23 August 2017

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Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1.

23 August 2017

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Cytochrome P450 enzymes: novel options for cancer therapeutics.

23 August 2017

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Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta

23 August 2017

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Oxidative stress, toxicology, and pharmacology of CYP2E1.

23 August 2017

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A trip to the ER: coping with stress

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

23 August 2017

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23 August 2017

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6 September 2017

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6 September 2017

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CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases

6 September 2017

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6 September 2017

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14 September 2017

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14 September 2017

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28 September 2017

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28 September 2017

1 reference

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23 June 2018

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Brain drug-metabolizing cytochrome P450 enzymes are active in vivo, demonstrated by mechanism-based enzyme inhibition.

23 June 2018

1 reference

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Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen

23 June 2018

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Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1.

1 September 2018

1 reference

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Evidence of oxidative stress and associated DNA damage, increased proliferative drive, and altered gene expression in rat liver produced by the cholangiocarcinogenic agent furan

1 September 2018

1 reference

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1 September 2018

1 reference

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Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression.

1 September 2018

1 reference

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1 September 2018

1 reference

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Induction of tubulin by docetaxel is associated with p53 status in human non small cell lung cancer cell lines.

1 September 2018

1 reference

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Immunohistochemical evaluation of cytochrome P450 (CYP) and p53 in breast cancer

1 September 2018

1 reference

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1 September 2018

1 reference

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1 September 2018

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1 September 2018

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RNA expression of cytochrome P450 in breast cancer patients

21 January 2018

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12 December 2020

Chlormethiazole as an efficient inhibitor of cytochrome P450 2E1 expression in rat liver

1 reference

12 December 2020

Immunohistochemical study of CYP2E1 in hepatocellular carcinoma carcinogenesis: examination with newly prepared anti-human CYP2E1 antibody

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Decreased Cyp2E1 mRNA expression in human leucocytes in patients with fibrotic and inflammatory lung diseases

1 reference

12 December 2020

Immunohistochemical demonstration of the expression of CYP2E1 in human breast tumour and non-tumour tissues

1 reference

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PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells

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p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements

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Identifiers

DOI

10.1186/BCR3574

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24207099%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24207099%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

24207099

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24207099%20AND%20SRC:MED&resulttype=core&format=json