Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells. (Q37690257)

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21 February 2020

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26 August 2020

Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells (English)

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21 February 2020

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20 November 2019

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26 August 2020

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26 August 2020

neoplastic stem cells

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1 reference

3

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21 February 2020

Gillian Farnie

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21 February 2020

Robert B. Clarke

5

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21 February 2020

author name string

Jagdeep K Singh

1

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21 February 2020

Bruno M Simões

2

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publication date

1 January 2013

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21 February 2020

published in

Breast Cancer Research

6 references

13 March 2019

3 April 2019

17 June 2019

20 November 2019

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21 February 2020

26 August 2020

15

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21 February 2020

issue

4

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21 February 2020

page(s)

210

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https://scigraph.springernature.com/pub.10.1186/bcr3436

21 February 2020

exact match

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: a rationale for cotargeting these pathways in metastatic breast cancer

23 August 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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14 September 2017

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Interleukin-8 modulates growth and invasiveness of estrogen receptor-negative breast cancer cells

14 September 2017

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14 September 2017

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CXCL8-induced FAK phosphorylation via CXCR1 and CXCR2: cytoskeleton- and integrin-related mechanisms converge with FAK regulatory pathways in a receptor-specific manner

14 September 2017

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The angiogenic factors CXCL8 and VEGF in breast cancer: regulation by an array of pro-malignancy factors.

14 September 2017

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Mechanisms involved in Helicobacter pylori-induced interleukin-8 production by a gastric cancer cell line, MKN45.

14 September 2017

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Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo

14 September 2017

1 reference

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Progression and enhancement of metastatic potential after exposure of tumor cells to chemotherapeutic agents

28 September 2017

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Interleukin 8 expression regulates tumorigenicity and metastasis in human bladder cancer

28 September 2017

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Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils

28 September 2017

1 reference

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Purification and partial biochemical characterization of a human monocyte-derived, neutrophil-activating peptide that lacks interleukin 1 activity.

23 June 2018

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Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells.

23 June 2018

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Interleukin-8 as a macrophage-derived mediator of angiogenesis

23 June 2018

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Breast cancer stem cells: we've got them surrounded

23 June 2018

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CXC chemokines located in the 4q21 region are up-regulated in breast cancer.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978717

Reparixin, a specific interleukin-8 inhibitor, has no effects on inflammation during endotoxemia.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978717

HER2 signaling modulates the equilibrium between pro- and antiangiogenic factors via distinct pathways: implications for HER2-targeted antibody therapy.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978717

Roots and stems: stem cells in cancer.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978717

Ligand selectivity and affinity of chemokine receptor CXCR1. Role of N-terminal domain

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978717

Identification of interleukin-8 as estrogen receptor-regulated factor involved in breast cancer invasion and angiogenesis by protein arrays.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978717

Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978717

IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978717

IL-8 as Antibody Therapeutic Target in Inflammatory Diseases: Reduction of Clinical Activity in Palmoplantar Pustulosis

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FBCR3436

Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells

21 January 2018

1 reference

12 December 2020

Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival

1 reference

12 December 2020

Serum IL-8 and IL-12 levels in breast cancer

1 reference

12 December 2020

IL-1 alpha or tumor necrosis factor-alpha stimulate release of three NAP-1/IL-8-related neutrophil chemotactic proteins in human dermal fibroblasts

1 reference

12 December 2020

Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial

1 reference

12 December 2020

Endothelial interleukin-8: a novel inhibitor of leukocyte-endothelial interactions

1 reference

12 December 2020

Phase Ib Pilot Study to Evaluate Reparixin in Combination with Weekly Paclitaxel in Patients with HER-2-Negative Metastatic Breast Cancer.

1 reference

12 December 2020

Structure determination of a human lymphocyte derived neutrophil activating peptide (LYNAP)

1 reference

12 December 2020

Purification and amino acid sequencing of NAF, a novel neutrophil-activating factor produced by monocytes

1 reference

12 December 2020

Structural requirements for interleukin-8 function identified by design of analogs and CXC chemokine hybrids

1 reference

12 December 2020

Expression of cytokine messenger RNA in normal and neoplastic human breast tissue: Identification of interleukin-8 as a potential regulatory factor in breast tumours

1 reference

12 December 2020

Expression of interleukin-8 receptors on tumor cells and vascular endothelial cells in human breast cancer tissue

1 reference

12 December 2020

Identifiers

DOI

10.1186/BCR3436

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24041156%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

21 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24041156%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24041156%20AND%20SRC:MED&resulttype=core&format=json