High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial (Q37682595)

22 August 2017

High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial (English)

1 reference

22 August 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Irina S Babina

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Amanda Swain

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Sanjay Popat

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

David Cunningham

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

12

James Campbell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Alex Pearson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Maria Teresa Herrera-Abreu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Noelia Tarazona

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Clare Peckitt

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Elaine Kilgour

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Neil R Smith

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Catherine Geh

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Claire Rooney

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Ros Cutts

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jian Ning

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Kerry Fenwick

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Gina Brown

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Sue Chua

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Anne Thomas

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Stephen R D Johnston

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Mazhar Ajaz

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Katherine Sumpter

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Angela Gillbanks

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

David Watkins

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Ian Chau

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Nicholas C Turner

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

publication date

13 May 2016

1 reference

22 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

838-851

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

Comprehensive molecular characterization of gastric adenocarcinoma

6 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Determination of HER2 amplification status on tumour DNA by digital PCR

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Requirement for interaction of PI3-kinase p110α with RAS in lung tumor maintenance

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Fibroblast growth factor signalling: from development to cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Drug combination studies and their synergy quantification using the Chou-Talalay method

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

The FGF23-Klotho axis: endocrine regulation of phosphate homeostasis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

The bimodality index: a criterion for discovering and ranking bimodal signatures from cancer gene expression profiling data

23 August 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

23 August 2017

https://pubmed.ncbi.nlm.nih.gov/27179038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fast and accurate short read alignment with Burrows-Wheeler transform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Disease-free survival according to degree of HER2 amplification for patients treated with adjuvant chemotherapy with or without 1 year of trastuzumab: the HERA Trial

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Aberrant receptor internalization and enhanced FRS2-dependent signaling contribute to the transforming activity of the fibroblast growth factor receptor 2 IIIb C3 isoform

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Deletion of the carboxyl-terminal exons of K-sam/FGFR2 by short homology-mediated recombination, generating preferential expression of specific messenger RNAs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Fibroblast growth factor receptor inhibitors as a cancer treatment: from a biologic rationale to medical perspectives

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Noninvasive detection of HER2 amplification with plasma DNA digital PCR.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update

14 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

2 October 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5338732

10.1158/2159-8290.CD-15-1246

3 December 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27179038%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference