Proteinuria and events beyond the slit (Q37668154)

21 August 2017

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title

Proteinuria and events beyond the slit (English)

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21 August 2017

Rikke Nielsen

1

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PubMed ID

20049615

21 August 2017

Erik Ilsø Christensen

series ordinal

2

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PubMed ID

20049615

21 August 2017

language of work or name

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5 January 2010

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21 August 2017

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21 August 2017

25

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21 August 2017

5

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21 August 2017

813-822

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https://scigraph.springernature.com/pub.10.1007/s00467-009-1381-9

21 August 2017

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Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules

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Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins

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Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules

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Independent two-photon measurements of albumin GSC give low values

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Cubilin is an albumin binding protein important for renal tubular albumin reabsorption

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Proteinuria in cubilin-deficient patients with selective vitamin B12 malabsorption

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A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis

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Cloning and sequencing of human gp330, a Ca(2+)-binding receptor with potential intracellular signaling properties

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The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins

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Segmental distribution of the endocytosis receptor gp330 in renal proximal tubules

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Glomerular sieving coefficient of serum albumin in the rat: a two-photon microscopy study

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Molecular and cellular basis of lysosomal transmembrane protein dysfunction

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12 December 2020

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Defective forebrain development in mice lacking gp330/megalin

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Donnai-Barrow syndrome (DBS/FOAR) in a child with a homozygous LRP2 mutation due to complete chromosome 2 paternal isodisomy

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12 December 2020

A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

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12 December 2020

Effects of receptor-mediated endocytosis and tubular protein composition on volume retention in experimental glomerulonephritis

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12 December 2020

Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor

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12 December 2020

Urinary protein excretion pattern and renal expression of megalin and cubilin in nephropathic cystinosis

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12 December 2020

Mutations in CUBN, encoding the intrinsic factor-vitamin B12 receptor, cubilin, cause hereditary megaloblastic anaemia 1

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12 December 2020

Albumin concentration in the Bowman's capsule: Multiphoton microscopy vs micropuncture technique

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12 December 2020

39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein

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12 December 2020

Renal albumin handling: a look at the dark side of the filter

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12 December 2020

Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate

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12 December 2020

RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors

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12 December 2020

Identification of an apical sorting determinant in the cytoplasmic tail of megalin

1 reference

12 December 2020

Controversies in nephrology: renal albumin handling, facts, and artifacts!

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12 December 2020

Intra-renal and subcellular distribution of the human chloride channel, CLC-5, reveals a pathophysiological basis for Dent's disease

1 reference

12 December 2020

Megalin knockout mice as an animal model of low molecular weight proteinuria.

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12 December 2020

ClC-5, the chloride channel mutated in Dent's disease, colocalizes with the proton pump in endocytotically active kidney cells

1 reference

12 December 2020

Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor

1 reference

12 December 2020

Imerslund-Gräsbeck syndrome (selective vitamin B(12) malabsorption with proteinuria)

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12 December 2020

Pathways to nephron loss starting from glomerular diseases-insights from animal models

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12 December 2020

Nephropathic cystinosis: late complications of a multisystemic disease

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12 December 2020

Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis

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12 December 2020

Lowe syndrome protein OCRL1 interacts with clathrin and regulates protein trafficking between endosomes and the trans-Golgi network

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12 December 2020

Rapid membrane recycling in renal proximal tubule cells

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12 December 2020

How does proteinuria cause progressive renal damage?

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12 December 2020

On the origin of albuminuria

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12 December 2020

Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin

1 reference

12 December 2020

Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo

1 reference

12 December 2020

A cytoplasmic PPPSP motif determines megalin's phosphorylation and regulates receptor's recycling and surface expression

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12 December 2020

Membrane receptors for endocytosis in the renal proximal tubule.

1 reference

12 December 2020

Selective vitamin B12 malabsorption and proteinuria in young people. A syndrome.

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12 December 2020

Evidence for an essential role of megalin in transepithelial transport of retinol

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12 December 2020

A review of Donnai-Barrow and facio-oculo-acoustico-renal (DB/FOAR) syndrome: clinical features and differential diagnosis

1 reference

12 December 2020

The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless

1 reference

12 December 2020

The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrin

1 reference

12 December 2020

1 reference

12 December 2020

Idiopathic chronic megaloblastic anemia in children

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12 December 2020

GIPC is recruited by APPL to peripheral TrkA endosomes and regulates TrkA trafficking and signaling

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12 December 2020

Examination of megalin in renal tubular epithelium from patients with Dent disease.

1 reference

12 December 2020

The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border

1 reference

12 December 2020

Cubilin and megalin expression and their interaction in the rat intestine: effect of thyroidectomy

1 reference

12 December 2020

OCCURRENCE OF PHAGOSOMES AND PHAGO-LYSOSOMES IN DIFFERENT SEGMENTS OF THE NEPHRON IN RELATION TO THE REABSORPTION, TRANSPORT, DIGESTION, AND EXTRUSION OF INTRAVENOUSLY INJECTED HORSERADISH PEROXIDASE

1 reference

12 December 2020

Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module

1 reference

12 December 2020

Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3)

1 reference

12 December 2020

The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain

1 reference

12 December 2020

Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis

1 reference

12 December 2020

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells

1 reference

12 December 2020

ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease.

1 reference

12 December 2020

Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes

1 reference

12 December 2020

Early development of the renal lesions in infantile cystinosis

1 reference

12 December 2020

Long-term follow-up of well-treated nephropathic cystinosis patients

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12 December 2020

Cellular mechanisms of protein metabolism in the nephron. I. The structural aspects of proteinuria; tubular absorption, droplet formation, and the disposal of proteins

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12 December 2020

Ultrastructural localization by monoclonal antibodies of brush border antigens expressed by glomeruli. I. Renal distribution.

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12 December 2020

Effect of molecular charge on endocytic uptake of ferritin in renal proximal tubule cells

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12 December 2020

Type II phosphoinositide 5-phosphatases have unique sensitivities towards fatty acid composition and head group phosphorylation.

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12 December 2020

Isolation and partial characterization of a chloride channel gene which is expressed in kidney and is a candidate for Dent's disease (an X-linked hereditary nephrolithiasis).

1 reference

12 December 2020

10.1007/S00467-009-1381-9

Identifiers

DOI

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21 August 2017

1 reference

PubMed ID

20049615