Aging and immune function (Q37658072)

21 August 2017

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title

Aging and immune function (English)

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21 August 2017

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Miller RA

1

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21 August 2017

1 January 1991

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International Review of Cytology

21 August 2017

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21 August 2017

124

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21 August 2017

187-215

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Reducèd in vitro response to concanavalin A and lipopolysaccharide in senescent mice: a function of reduced number of responding cells

21 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Age-associated impairment of murine natural killer activity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Frequencies of mitogen-reactive B cells in the mouse. I. Distribution in different lymphoid organs from different inbred strains of mice at different ages

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Reduced T-lymphocyte cell reactivity as a function of human aging

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Influence of aging on T-cell subpopulations involved in the in vitro generation of allogeneic cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Reversal by lymphokines of the age-related hyporesponsiveness to contact sensitization and reduced Ia expression on Langerhans cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Absolute peripheral blood lymphocyte count and subsequent mortality of elderly men. The Baltimore Longitudinal Study of Aging

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Activation of resting human T cells requires prolonged stimulation of protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Suppression of natural killer cell activity in young and old mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Interleukin-1 synthesis and activity in aged mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Immune function in aged mice IV. Loss of T cell and B cell function in thymus-dependent antibody responses

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Decline in the production of interleukin-3 with age in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Interleukin 2, interleukin 2 receptor, and interferon-gamma synthesis and mRNA expression in phorbol myristate acetate and calcium ionophore A23187-stimulated T cells from elderly humans

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Alterations in the human immune response to the hepatitis B vaccine among the elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Sex differences in lectin-induced interleukin-2 synthesis in aging rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Abolished in vitro antibody response in elderly: exclusive involvement of prostaglandin-induced T suppressor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

The effect of age on the antigen-presenting mechanism in limiting dilution precursor cell frequency analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Diminished heat-shock protein synthesis following mitogen stimulation of lymphocytes from aged donors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Decreased sympathetic innervation of spleen in aged Fischer 344 rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Loss of tumor-specific and idiotype-specific immunity with age

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

In situ hybridization analysis of the age-associated decline in IL-2 mRNA expressing murine T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Enhanced frequency of mitogen-responsive T cell precursors in old mice injected with thymosin alpha 1

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Induction of increased calcium uptake in mouse T lymphocytes by concanavalin A and its modulation by cyclic nucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Phytohemagglutinin induced proliferation by aged lymphocytes: reduced expression of high affinity interleukin-2 receptors and interleukin-2 secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Uptake of extracellular Ca2+ and not recruitment from internal stores is essential for T lymphocyte proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Increased natural resistance to Listeria monocytogenes in senescent mice correlates with enhanced macrophage bactericidal activity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Effect of chronologic aging and ultraviolet irradiation on Langerhans cells in human epidermis.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Production of auto-anti-idiotypic antibody during the normal immune response: changes in the auto-anti-idiotypic antibody response and the idiotype repertoire associated with aging

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Production of auto-antiidiotypic antibody during the normal immune response. VII. Analysis of the cellular basis for the increased auto-antiidiotype antibody production by aged mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Sensitivity of lymphocytes to prostaglandin E2 increases in subjects over age 70

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Proliferative and cytotoxic immune functions in aging mice. III. Exogenous interleukin-2 rich supernatant only partially restores alloreactivity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Selective decline in differentiating capacity of immunohemopoietic stem cells with aging

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Regulatory effects of thymus humoral factor on T cell growth factor in aging mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Reduced proliferation in T lymphocytes in aged humans is predominantly in the CD8+ subset, and is unrelated to defects in transmembrane signaling which are predominantly in the CD4+ subset

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Enhanced in vitro bone marrow cell migration and T-lymphocyte responses in aged mice given subcutaneous thymic epithelial cell grafts

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Age-associated changes in proliferative and differentiative response of human B cells and production of T cell-derived factors regulating B cell functions

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Loss of proliferative capacity in immunohemopoietic stem cells caused by serial transplantation rather than aging

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Murine CD4+ T cell subsets defined

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Phenotypic and functional alteration of CD4+ T cells after antigen stimulation. Resolution of two populations of memory T cells that both secrete interleukin 4

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Restoration of impaired immune functions in aging animals. II. Effect of syngeneic thymus and bone marrow grafts

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Restoration of impaired immune functions in aging animals. V. Long-term immunopotentiating effects of combined young bone marrow and newborn thymus grafts

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Expression of interleukin 2 and the interleukin 2 receptor in aging rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Decline in Phytohemagglutinin Responsiveness of Spleen Cells from Aging Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

B cell stimulatory factor 1 (interleukin 4) is a potent costimulant for normal resting T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Immunological studies of Aging. III. Cytokinetic basis for the impaired response of lymphocytes from aged humans to plant lectins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Alterations in the proliferative response of T cells from aged and chimeric mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Fever in the elderly. Production of leukocytic pyrogen by monocytes from elderly persons

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Endogenous pyrogen/interleukin-1 production in aged rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Lymphokine-activated killer cells and aging in mice: significance for defining the precursor cell.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Lymphokine-activated killer cells derived from murine bone marrow: age-associated difference in precursor cell populations demonstrated by response to interferon

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

GH3 pituitary adenoma cells can reverse thymic aging in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Bone marrow function. I. Peripheral T cells are responsible for the increased auto-antiidiotype response of older mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Antibody-specific immunoregulation and the immunodeficiency of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Functional competence of dendritic cells of ageing C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Age-associated alterations in human natural killer cells. 2. Increased frequency of selective NK subsets

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

BrdU-Hoechst flow cytometry reveals regulation of human lymphocyte growth by donor-age-related growth fraction and transition rate

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Pgp-1hi T lymphocytes accumulate with age in mice and respond poorly to concanavalin A.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Aging and the mobilization of intracellular calcium by phytohemagglutinin in human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Immunological studies of aging. Normal B-cell repertoire in aged mice: studies at a clonal level

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Cell-mediated immunity of healthy adult Nova Scotians in various age groups compared with nursing home and hospitalized senior citizens

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

The role of T cell phenotypes in decreased lymphoproliferation of the elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Age-associated increase in the expression of T cell antigen receptor gamma chain genes in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

In vivo immunopotentiating activity of thymopentin in aging humans: increase of IL-2 production

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Vitamin E supplementation suppresses prostaglandin E1(2) synthesis and enhances the immune response of aged mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Decline, in aging mice, of the anti-2,4,6-trinitrophenyl (TNP) cytotoxic T cell response attributable to loss of Lyt-2-, interleukin 2-producing helper cell function

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Diminished calcium influx in lectin-stimulated T cells from old mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Defective control of cytoplasmic calcium concentration in T lymphocytes from old mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

The immune response in aged C57BL/6 mice. I. Assessment of lesions in the B-cell and T-cell compartments of aged mice utilizing the Fc fragment-mediated polyclonal antibody response

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Immunologic response in an elderly population with a mean age of 85

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Mechanisms of age-related decline in antigen-specific T cell proliferative response: IL-2 receptor expression and recombinant IL-2 induced proliferative response of purified Tac-positive T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Effects on immune responses by chronic stress are modulated by aging

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Expression of the human T cell antigen receptor complex in advanced age

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

A mouse model of the recrudescence of latent tuberculosis in the elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Aging and antimicrobial immunity. Impaired production of mediator T cells as a basis for the decreased resistance of senescent mice to listeriosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Antigen presentation by peritoneal macrophages from young adult and old mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

T lymphocyte heterogeneity in old and young mice: functional defects in T cells selected for poor calcium signal generation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Diminished calcium signal generation in subsets of T lymphocytes that predominate in old mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Studies of human natural killer cells. I. In vivo parameters affecting normal cytotoxic function

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Aging in man. Linear increase of a novel T cell subset defined by antiganglioside monoclonal antibody 3G5

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Ageing, immune response, and mortality

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Interferon response to mitogens and viral antigens in elderly and young adult subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Human naive and memory T cells: reinterpretation of helper-inducer and suppressor-inducer subsets

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

The phytohemagglutinin response of human peripheral blood lymphocytes as a function of donor age: a re-examination using BrdU-Hoechst flow cytometry

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Thymus cell migration. Quantitative aspects of cellular traffic from the thymus to the periphery in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Studies on the age-related decline in the response of lymphoid cells to mitogens: measurements of concanavalin A binding and stimulation of calcium and sugar uptake in thymocytes from rats of varying ages

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Increased expression of major histocompatibility complex antigens on lymphocytes from aged mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Physiology of IgD. IX. Effect of IgD on immunoglobulin production in young and old mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Loss of immune competence with age may be due to auto-anti-idiotypic antibody regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Partial restoration of Con A-induced proliferation, IL-2 receptor expression, and IL-2 synthesis in aged murine lymphocytes by phorbol myristate acetate and ionomycin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

The immune status of healthy centenarians.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Cytokinetic analysis of the impaired proliferative response of peripheral lymphocytes from aged humans to phytohemagglutinin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Old mice recover the ability to produce IgG and high-avidity antibody following irradiation with partial bone marrow shielding

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

The influence of T cells on homogeneous immunoglobulins in sera of athymic nude mice during aging

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Decline, with age, in the proportion of mouse T cells that express IL-2 receptors after mitogen stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Cell-mediated immunity as a predictor of morbidity and mortality in subjects over 60

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Increased proliferative response of human peripheral blood lymphocytes to anti-immunoglobulin antibodies in elderly people

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Peripheral T cells select the B-cell repertoire in old mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

The effect of aging on the expression of interleukin 2 messenger ribonucleic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

T cell involvement in the decrease of antigen-responsive B cells in aged mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

Antigen responsiveness of the mature and generative B cell populations of aged mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2961527-2

7 January 2021

10.1016/S0074-7696(08)61527-2

Identifiers

DOI

0 references

PubMed ID

2001916

1 reference

PubMed ID

2001916