Various drug delivery approaches to the central nervous system (Q37657525)

21 August 2017

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title

Various drug delivery approaches to the central nervous system (English)

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21 August 2017

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Santosh Pasha

1

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PubMed ID

20017662

21 August 2017

Kshitij Gupta

series ordinal

2

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PubMed ID

20017662

21 August 2017

language of work or name

English

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publication date

1 January 2010

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Expert Opinion on Drug Delivery

21 August 2017

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21 August 2017

7

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21 August 2017

1

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21 August 2017

113-135

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Progress in drug delivery to the central nervous system by the prodrug approach.

21 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

The blood-brain barrier and cancer: transporters, treatment, and Trojan horses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Delivery of therapeutic agents to the central nervous system: the problems and the possibilities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Blood-brain barrier delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

ABC transporters and the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Peptide drug modifications to enhance bioavailability and blood-brain barrier permeability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

The CNS as a target for peptides and peptide-based drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Flurbiprofen derivatives in Alzheimer's disease: synthesis, pharmacokinetic and biological assessment of lipoamino acid prodrugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Azomethine prodrugs of (R)-alpha-methylhistamine, a highly potent and selective histamine H3-receptor agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Improved brain delivery of a nonsteroidal anti-inflammatory drug with a synthetic glyceride ester: a preliminary attempt at a CNS drug delivery system for the therapy of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Determination of m-nitrophenol and nipecotic acid in mouse tissues by high-performance liquid chromatography after administration of the anticonvulsant m-nitrophenyl-3-piperidinecarboxylate hydrochloride.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Synthesis and characterization of 9-[P-(N, N-dipropyl sulfamide)] benzoylamino-1,2,3,4-4H-acridine--a potential prodrug for the CNS delivery of tacrine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

DP-155, a lecithin derivative of indomethacin, is a novel nonsteroidal antiinflammatory drug for analgesia and Alzheimer's disease therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

A strategy for delivering peptides into the central nervous system by sequential metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Interaction of nucleoside analogues with nucleoside transporters in rat brain endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

L-DOPA transport properties in an immortalised cell line of rat capillary cerebral endothelial cells, RBE 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Prodrug approaches for CNS delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Synthesis, conformational and pharmacological studies of glycosylated chimeric peptides of Met-enkephalin and FMRFa

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Large neutral amino acid transporter enables brain drug delivery via prodrugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Design, synthesis and biological evaluation of glutathione peptidomimetics as components of anti-Parkinson prodrugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Design, synthesis and activity of ascorbic acid prodrugs of nipecotic, kynurenic and diclophenamic acids, liable to increase neurotropic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Targeted delivery of a peripheral benzodiazepine receptor ligand-gemcitabine conjugate to brain tumors in a xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Delivery of peptide and protein drugs over the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Transcytotic pathway for blood-borne protein through the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Characterization of the catalytic cycle of ATP hydrolysis by human P-glycoprotein. The two ATP hydrolysis events in a single catalytic cycle are kinetically similar but affect different functional outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Pumping of Drugs by P-Glycoprotein: A Two-Step Process?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Pluronic block copolymers as modulators of drug efflux transporter activity in the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Protein transduction technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Intracellular cargo delivery using tat peptide and derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Cell-penetrating peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Tat-mediated delivery of heterologous proteins into cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

In vivo protein transduction: delivery of a biologically active protein into the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Intravenous TAT-Bcl-Xl is protective after middle cerebral artery occlusion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Osmotic opening of the blood-brain barrier: principles, mechanism, and therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Intracarotid administration of short-chain alkylglycerols for increased delivery of methotrexate to the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Chemical induction of fenestrae in vessels of the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Peripheral injections of Freund's adjuvant in mice provoke leakage of serum proteins through the blood-brain barrier without inducing reactive gliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Selective blood-tumor barrier disruption by leukotrienes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

The development of the bradykinin agonist labradimil as a means to increase the permeability of the blood-brain barrier: from concept to clinical evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Intravenous cereport (RMP-7) enhances delivery of hydrophilic chemotherapeutics and increases survival in rats with metastatic tumors in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Ultrasound-induced mild hyperthermia as a novel approach to increase drug uptake in brain microvessel endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Colloidal carriers and blood-brain barrier (BBB) translocation: a way to deliver drugs to the brain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Polymeric nanoparticles for the drug delivery to the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Delivering drugs to the central nervous system: a medicinal chemistry or a pharmaceutical technology issue?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

New technologies for drug delivery across the blood brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Tetanus toxin C fragment-conjugated nanoparticles for targeted drug delivery to neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Nanoparticulate systems for brain delivery of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Challenges and opportunities in CNS delivery of therapeutics for neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Recent advances in medicinal chemistry and pharmaceutical technology--strategies for drug delivery to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Binding and uptake of biodegradable poly-DL-lactide micro- and nanoparticles in intestinal epithelia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Multifunctional nanocarriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Targeting the central nervous system: in vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Specific role of polysorbate 80 coating on the targeting of nanoparticles to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Tumor-specific targeting of sodium borocaptate (BSH) to malignant glioma by transferrin-PEG liposomes: a modality for boron neutron capture therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Liposome encapsulated polyethylenimine/ODN polyplexes for brain targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Dual-targeting topotecan liposomes modified with tamoxifen and wheat germ agglutinin significantly improve drug transport across the blood-brain barrier and survival of brain tumor-bearing animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Delivery of sodium borocaptate to glioma cells using immunoliposome conjugated with anti-EGFR antibodies by ZZ-His.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Surface modification of RGD-liposomes for selective drug delivery to monocytes/neutrophils in brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Nanoparticles of cationic chimeric peptide and sodium polyacrylate exhibit striking antinociception activity at lower dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Development of a smart nano-vehicle to target cerebrovascular amyloid deposits and brain parenchymal plaques observed in Alzheimer's disease and cerebral amyloid angiopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Preparation of estradiol chitosan nanoparticles for improving nasal absorption and brain targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Solid lipid nanoparticles for targeted brain drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Body distribution of camptothecin solid lipid nanoparticles after oral administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Intravenous administration to rabbits of non-stealth and stealth doxorubicin-loaded solid lipid nanoparticles at increasing concentrations of stealth agent: pharmacokinetics and distribution of doxorubicin in brain and other tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Targeting anticancer drugs to the brain. I: Enhanced brain delivery of oxantrazole following administration in magnetic cationic microspheres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Polypeptide point modifications with fatty acid and amphiphilic block copolymers for enhanced brain delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG-TAT for drug delivery across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Polymeric micelles anchored with TAT for delivery of antibiotics across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Pharmacometrics and delivery of novel nanoformulated PEG-b-poly(epsilon-caprolactone) micelles of rapamycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Methotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: enhanced efficacy and intratumoral transport capability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Nasal drug delivery--possibilities, problems and solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

The Transport of a Drug to the Cerebrospinal Fluid Directly from the Nasal Cavity: The Relation to the Lipophilicity of the Drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Direct drug transport from the rat nasal cavity to the cerebrospinal fluid: the relation to the molecular weight of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Evaluation of brain-targeting for the nasal delivery of estradiol by the microdialysis method.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Bicarbonate-dependent depolarizing potentials in pyramidal cells and interneurons during epileptiform activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Progesterone for the treatment of experimental brain injury; a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Intranasal deferoxamine provides increased brain exposure and significant protection in rat ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Convection-enhanced delivery of nanocarriers for the treatment of brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Convection-enhanced delivery of macromolecules in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Enhanced survival and cure of F98 glioma-bearing rats following intracerebral delivery of carboplatin in combination with photon irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Convection-enhanced delivery of immunotoxins and radioisotopes for treatment of malignant gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Convection-enhanced and local delivery of targeted cytotoxins in the treatment of malignant gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Convection-enhanced delivery of tumor necrosis factor-related apoptosis-inducing ligand with systemic administration of temozolomide prolongs survival in an intracranial glioblastoma xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Convection-enhanced delivery of maghemite nanoparticles: Increased efficacy and MRI monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Convection-enhanced delivery in the treatment of epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Prolonged attenuation of amygdala-kindled seizure measures in rats by convection-enhanced delivery of the N-type calcium channel antagonists omega-conotoxin GVIA and omega-conotoxin MVIIA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Salirasib (farnesyl thiosalicylic acid) for brain tumor treatment: a convection-enhanced drug delivery study in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Convection-enhanced delivery of nanoliposomal CPT-11 (irinotecan) and PEGylated liposomal doxorubicin (Doxil) in rodent intracranial brain tumor xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Convection-enhanced delivery of Ls-TPT enables an effective, continuous, low-dose chemotherapy against malignant glioma xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Convection-enhanced delivery of a topoisomerase I inhibitor (nanoliposomal topotecan) and a topoisomerase II inhibitor (pegylated liposomal doxorubicin) in intracranial brain tumor xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

188Re-loaded lipid nanocapsules as a promising radiopharmaceutical carrier for internal radiotherapy of malignant gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

In vivo demonstration of subcellular localization of anti-transferrin receptor monoclonal antibody-colloidal gold conjugate in brain capillary endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

Computational Approaches for the Prediction of Blood-Brain Barrier Permeation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903405581

10.1517/17425240903405581

21 January 2018

Identifiers

DOI

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2hl5pcyv6nf2vpcvd2zhsuisxq

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Fatcat ID

release_2hl5pcyv6nf2vpcvd2zhsuisxq

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Fatcat

https://api.fatcat.wiki/v0/release/2hl5pcyv6nf2vpcvd2zhsuisxq

mapped directly with Wikidata item

30 July 2022

based on heuristic

1 reference

https://api.fatcat.wiki/v0/release/2hl5pcyv6nf2vpcvd2zhsuisxq