Differential requirements for IL-4/STAT6 signalling in CD4 T-cell fate determination and Th2-immune effector responses (Q37654752)

21 August 2017

1 reference

title

Differential requirements for IL-4/STAT6 signalling in CD4 T-cell fate determination and Th2-immune effector responses (English)

1 reference

21 August 2017

4

Graham Le Gros

1 reference

21 August 2017

Elizabeth Forbes

1

1 reference

21 August 2017

Nicholas van Panhuys

series ordinal

2

1 reference

21 August 2017

Booki Min

series ordinal

3

1 reference

21 August 2017

15 December 2009

1 reference

Immunology & Cell Biology

21 August 2017

1 reference

21 August 2017

88

1 reference

21 August 2017

3

1 reference

21 August 2017

240-243

1 reference

https://scigraph.springernature.com/pub.10.1038/icb.2009.101

21 August 2017

0 references

cites work

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

IL-9 as a mediator of Th17-driven inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Cytokine-secreting follicular T cells shape the antibody repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Animal model of Nippostrongylus brasiliensis and Heligmosomoides polygyrus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Atopic dermatitis: new insights and opportunities for therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Limited T-cell receptor diversity predisposes to Th2 immunopathology: involvement of Tregs and conventional CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

MyD88-dependent induction of allergic Th2 responses to intranasal antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Interleukin-18 regulates both Th1 and Th2 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Dendritic-cell control of pathogen-driven T-cell polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Alarming dendritic cells for Th2 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Cutting edge: dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminth-specific Th2 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

CD4 T cells: fates, functions, and faults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Interleukin 2 plays a central role in Th2 differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Stat6 regulation of in vivo IL-4 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Cutting edge: Th2 cell trafficking into the allergic lung is dependent on chemoattractant receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

IL-13 is necessary, not simply sufficient, for epicutaneously induced Th2 responses to soluble protein antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Lymphocyte traffic control by chemokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Differential T cell function and fate in lymph node and nonlymphoid tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Regulation of IgE synthesis in humans: a tale of two signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Interleukin-13: central mediator of allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Selective maturation of dendritic cells byNippostrongylus brasiliensis-secreted proteins drives Th2 immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

Role of TGF-Beta in the induction of Foxp3 expression and T regulatory cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

7 January 2021

Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

7 January 2021

The antigen dose determines T helper subset development by regulation of CD40 ligand

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

7 January 2021

How C-type lectins detect pathogens

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

7 January 2021

Parasite-induced Th2 polarization is associated with down-regulated dendritic cell responsiveness to Th1 stimuli and a transient delay in T lymphocyte cycling

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

7 January 2021

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

7 January 2021

Stat5 activation plays a critical role in Th2 differentiation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

7 January 2021

Interleukin-13 in asthma pathogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

7 January 2021

Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gamma

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.101

7 January 2021

Identifiers

DOI

10.1038/ICB.2009.101

1 reference

Dimensions Publication ID

21 August 2017

0 references

1 reference