Role of the sarcomeric Z-disc in the pathogenesis of cardiomyopathy (Q37608582)

21 August 2017

title

Role of the sarcomeric Z-disc in the pathogenesis of cardiomyopathy (English)

1 reference

21 August 2017

0 references

3

Hugo A Katus

1 reference

21 August 2017

Derk Frank

1

1 reference

21 August 2017

Christian Kuhn

series ordinal

2

1 reference

21 August 2017

Norbert Frey

series ordinal

4

1 reference

21 August 2017

publication date

1 November 2007

1 reference

21 August 2017

1 reference

21 August 2017

volume

3

1 reference

21 August 2017

issue

6

1 reference

21 August 2017

page(s)

611-622

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

21 August 2017

1 reference

The genetic basis for cardiac remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Frequency and phenotypes of familial dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Molecular genetics and genomics of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Isolated ventricular non-compaction of the myocardium in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

The sarcomeric Z-disc: a nodal point in signalling and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Costameres: the Achilles' heel of Herculean muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

At the crossroads of myocardial signaling: the role of Z-discs in intracellular signaling and cardiac function.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

A common nonsense mutation results in alpha-actinin-3 deficiency in the general population.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Alpha-actinin revisited: a fresh look at an old player

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Interaction of PKN with alpha-actinin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Characterization of lethal Drosophila melanogaster alpha-actinin mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Mutations in the muscle LIM protein and α-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Regulating actin-filament dynamics in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Actin-based motility: from molecules to movement

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Striated muscle cytoarchitecture: an intricate web of form and function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Actin mutations in dilated cardiomyopathy, a heritable form of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Alpha-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Mutation in the alpha-cardiac actin gene associated with apical hypertrophic cardiomyopathy, left ventricular non-compaction, and septal defects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Gene mutations in apical hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Functional consequences of a mutation in an expressed human alpha-cardiac actin at a site implicated in familial hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Rescue of cardiac alpha-actin-deficient mice by enteric smooth muscle gamma-actin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

The giant protein titin: a major player in myocardial mechanics, signaling, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Two immunoglobulin-like domains of the Z-disc portion of titin interact in a conformation-dependent way with telethonin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

The kinase domain of titin controls muscle gene expression and protein turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Depletion of zebrafish titin reduces cardiac contractility by disrupting the assembly of Z-discs and A-bands

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Structural analysis of the titin gene in hypertrophic cardiomyopathy: identification of a novel disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

C-terminal titin deletions cause a novel early-onset myopathy with fatal cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Identification of a novel frameshift mutation in the giant muscle filament titin in a large Australian family with dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Titin mutations as the molecular basis for dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Nebulin: the nebulous, multifunctional giant of striated muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Targeted disruption of nebulette protein expression alters cardiac myofibril assembly and function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Functional dissection of nebulette demonstrates actin binding of nebulin-like repeats and Z-line targeting of SH3 and linker domains

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

The complete mouse nebulin gene sequence and the identification of cardiac nebulin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Characterization of the human nebulette gene: a polymorphism in an actin-binding motif is associated with nonfamilial idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Stent treatment of coronary artery bifurcation lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Mutations in myotilin cause myofibrillar myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Myotilinopathy: refining the clinical and myopathological phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Myotilin is mutated in limb girdle muscular dystrophy 1A

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Muscle LIM protein, a novel essential regulator of myogenesis, promotes myogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Muscle LIM protein promotes myogenesis by enhancing the activity of MyoD

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Calsarcins, a novel family of sarcomeric calcineurin-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z-disc of skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Myozenin: an alpha-actinin- and gamma-filamin-binding protein of skeletal muscle Z lines

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Hypertrophy of the heart: a new therapeutic target?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Myozenin 2 is a novel gene for human hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

The NH2 terminus of titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Tcap gene mutations in hypertrophic cardiomyopathy and dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Myofilament calcium sensitivity and cardiac disease: insights from troponin I isoforms and mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

PDZ domains: structural modules for protein complex assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

The LIM domain is a modular protein-binding interface

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

ZASP: a new Z-band alternatively spliced PDZ-motif protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Cypher, a striated muscle-restricted PDZ and LIM domain-containing protein, binds to alpha-actinin-2 and protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Oracle, a novel PDZ-LIM domain protein expressed in heart and skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Characterization and in vivo functional analysis of splice variants of cypher

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Ablation of Cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

A Cypher/ZASP mutation associated with dilated cardiomyopathy alters the binding affinity to protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Echocardiographic-determined septal morphology in Z-disc hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Mutations in ZASP define a novel form of muscular dystrophy in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Desmin mutation responsible for idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Dystrophin: the protein product of the Duchenne muscular dystrophy locus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

The sarcoglycan complex in limb-girdle muscular dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Integrins and the myocardium.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Molecular and mechanical synergy: cross-talk between integrins and growth factor receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

In vitro interaction of a polypeptide homologous to human Ro/SS-A antigen (calreticulin) with a highly conserved amino acid sequence in the cytoplasmic domain of integrin alpha subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Immunological characterization of the subunit of the 100 A filaments from muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Molecular dissection of the interaction of desmin with the C-terminal region of nebulin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Synemin: a new high molecular weight protein associated with desmin and vimentin filaments in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Syncoilin, a novel member of the intermediate filament superfamily that interacts with alpha-dystrobrevin in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Disruption of muscle architecture and myocardial degeneration in mice lacking desmin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Desmin is essential for the tensile strength and integrity of myofibrils but not for myogenic commitment, differentiation, and fusion of skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

The absence of desmin leads to cardiomyocyte hypertrophy and cardiac dilation with compromised systolic function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Structural and functional roles of desmin in mouse skeletal muscle during passive deformation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Progressive skeletal myopathy, a phenotypic variant of desmin myopathy associated with desmin mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Early and sustained benefit on event-free survival and heart failure hospitalization from fixed-dose combination of isosorbide dinitrate/hydralazine: consistency across subgroups in the African-American Heart Failure Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Cardiac overexpression of melusin protects from dilated cardiomyopathy due to long-standing pressure overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Missense mutations in desmin associated with familial cardiac and skeletal myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

A dysfunctional desmin mutation in a patient with severe generalized myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

Fatal hypertrophic cardiomyopathy and nemaline myopathy associated with ACTA1 K336E mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796678.3.6.611

21 January 2018

Identifiers

DOI

10.2217/14796678.3.6.611

1 reference

21 August 2017

1 reference