B cells as therapeutic targets in SLE. (Q37603296)

21 August 2017

1 reference

title

B cells as therapeutic targets in SLE. (English)

1 reference

21 August 2017

1

Iñaki Sanz

1 reference

21 August 2017

F Eun-Hyung Lee

2

1 reference

PMCID

3934759

21 August 2017

language of work or name

English

0 references

publication date

1 June 2010

1 reference

Nature Reviews Rheumatology

21 August 2017

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21 August 2017

6

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21 August 2017

326-337

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21 August 2017

6

1 reference

https://scigraph.springernature.com/pub.10.1038/nrrheum.2010.68

21 August 2017

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23 August 2017

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Recent insights into the genetic basis of systemic lupus erythematosus

23 August 2017

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23 August 2017

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23 August 2017

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Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression

23 August 2017

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Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma

23 August 2017

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B cell depletion with anti-CD79 mAbs ameliorates autoimmune disease in MRL/lpr mice

23 August 2017

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Association of plasma B lymphocyte stimulator levels and disease activity in systemic lupus erythematosus

23 August 2017

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B-lymphocyte contributions to human autoimmune disease

23 August 2017

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Development of TLR inhibitors for the treatment of autoimmune diseases

23 August 2017

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A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses

23 August 2017

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Not always the bad guys: B cells as regulators of autoimmune pathology

23 August 2017

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23 August 2017

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23 August 2017

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Cutting edge: anti-tumor necrosis factor therapy in rheumatoid arthritis inhibits memory B lymphocytes via effects on lymphoid germinal centers and follicular dendritic cell networks

23 August 2017

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Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

23 August 2017

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23 August 2017

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Germinal-center organization and cellular dynamics

23 August 2017

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Novel suppressive function of transitional 2 B cells in experimental arthritis

23 August 2017

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Selective blockade of the inhibitory Fcgamma receptor (FcgammaRIIB) in human dendritic cells and monocytes induces a type I interferon response program

23 August 2017

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PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?

23 August 2017

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The BLyS/BAFF family of ligands and receptors: key targets in the therapy and understanding of autoimmunity

23 August 2017

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Competence and competition: the challenge of becoming a long-lived plasma cell

23 August 2017

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Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

23 August 2017

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Impact of the BAFF/BR3 axis on B cell survival, germinal center maintenance and antibody production

23 August 2017

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Selective dysregulation of the FcgammaIIB receptor on memory B cells in SLE

23 August 2017

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How does B cell depletion therapy work, and how can it be improved?

23 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934759

Immunotherapy using unconjugated CD19 monoclonal antibodies in animal models for B lymphocyte malignancies and autoimmune disease

23 August 2017

1 reference

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Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets

23 August 2017

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Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily

23 August 2017

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BAFF selectively enhances the survival of plasmablasts generated from human memory B cells.

23 August 2017

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B cells regulate autoimmunity by provision of IL-10.

23 August 2017

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The effect of anti-CD40 ligand antibody on B cells in human systemic lupus erythematosus

23 August 2017

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CD154-CD40 interactions mediate differentiation to plasma cells in healthy individuals and persons with systemic lupus erythematosus.

23 August 2017

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Lipopolysaccharide-activated B cells down-regulate Th1 immunity and prevent autoimmune diabetes in nonobese diabetic mice

23 August 2017

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CXCR4: chemokine receptor extraordinaire

23 August 2017

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Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen

23 August 2017

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TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production.

23 August 2017

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Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus.

6 September 2017

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Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells

14 September 2017

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Novel human transitional B cell populations revealed by B cell depletion therapy

14 September 2017

1 reference

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Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in MRL/lpr mice

25 June 2018

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Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial

25 June 2018

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Induction of interferon-alpha by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA.

25 June 2018

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IFN-alpha amplifies human naive B cell TLR-9-mediated activation and Ig production.

25 June 2018

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A retrospective seven-year analysis of the use of B cell depletion therapy in systemic lupus erythematosus at University College London Hospital: the first fifty patients

1 September 2018

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The proteasome inhibitor bortezomib inhibits the release of NFkappaB-inducible cytokines and induces apoptosis of activated T cells from rheumatoid arthritis patients.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934759

Highly sensitive B cell analysis predicts response to rituximab therapy in rheumatoid arthritis

1 September 2018

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The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis

1 September 2018

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An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus

1 September 2018

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TLR-activated B cells suppress T cell-mediated autoimmunity

1 September 2018

1 reference

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Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis.

1 September 2018

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PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934759

Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN.

1 September 2018

1 reference

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Mice deficient in OX40 and CD30 signals lack memory antibody responses because of deficient CD4 T cell memory.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3934759

Control of spontaneous B lymphocyte autoimmunity with adenovirus-encoded soluble TACI.

1 September 2018

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Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.

1 September 2018

1 reference

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Connective tissue diseases: The conundrum of B cell depletion in SLE

1 September 2018

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Inhibition of p38: has the fat lady sung?

2 October 2018

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Variability in the biological response to anti-CD20 B cell depletion in systemic lupus erythaematosus

21 January 2018

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Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus

3 December 2018

1 reference

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Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus

3 December 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.68

B cell depletion therapy in systemic lupus erythematosus: relationships among serum B lymphocyte stimulator levels, autoantibody profile and clinical response

31 March 2020

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New therapies in systemic lupus erythematosus--trials, troubles and tribulations--working towards a solution: part 2--the politically incorrect version

31 March 2020

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Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy

31 March 2020

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B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab

31 March 2020

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Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls

31 March 2020

1 reference

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FcγRIIb controls bone marrow plasma cell persistence and apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.68

A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.68

Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.68

Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.68

PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.68

IFN-alpha/beta enhances BCR-dependent B cell responses

31 March 2020

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Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.68

Type I IFN protects against murine lupus

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.68

Deficiency of type I interferon contributes to Sle2-associated component lupus phenotypes

31 March 2020

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Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.68

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.68

Cutting edge: primary B lymphocytes preferentially expand allogeneic FoxP3+ CD4 T cells

31 March 2020

1 reference

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Development of psoriasis after B cell depletion with rituximab

31 March 2020

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IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells

31 March 2020

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CXCL13 neutralization reduces the severity of collagen-induced arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.68

A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20520647

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRRHEUM.2010.68

1 reference

21 August 2017

1 reference

21 August 2017

1 reference

PMCID

3934759