Central nervous system regeneration inhibitors and their intracellular substrates (Q37599690)

21 August 2017

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title

Central nervous system regeneration inhibitors and their intracellular substrates (English)

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21 August 2017

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Michelle Nash

1

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21 August 2017

Horia Pribiag

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2

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21 August 2017

Alyson E Fournier

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3

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21 August 2017

Christian Jacobson

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4

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21 August 2017

19 September 2009

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21 August 2017

Molecular Neurobiology

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21 August 2017

40

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21 August 2017

3

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21 August 2017

224-235

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https://scigraph.springernature.com/pub.10.1007/s12035-009-8083-y

21 August 2017

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cites work

Reassessment of corticospinal tract regeneration in Nogo-deficient mice

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12 December 2020

Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation

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12 December 2020

Transcriptional regulation of scar gene expression in primary astrocytes

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12 December 2020

The N-terminal domain of Nogo-A inhibits cell adhesion and axonal outgrowth by an integrin-specific mechanism

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12 December 2020

Synaptic function for the Nogo-66 receptor NgR1: regulation of dendritic spine morphology and activity-dependent synaptic strength.

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12 December 2020

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

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12 December 2020

Multiple functions of the myelin-associated glycoprotein MAG (siglec-4a) in formation and maintenance of myelin

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12 December 2020

Patterns of Nogo mRNA and protein expression in the developing and adult rat and after CNS lesions.

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12 December 2020

Myelin-associated glycoprotein inhibits axonal regeneration from a variety of neurons via interaction with a sialoglycoprotein

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12 December 2020

Neuronal responses to myelin are mediated by rho kinase

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12 December 2020

Blockade of Nogo receptor ligands promotes functional regeneration of sensory axons after dorsal root crush.

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12 December 2020

Activated CREB is sufficient to overcome inhibitors in myelin and promote spinal axon regeneration in vivo

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12 December 2020

A class of membrane proteins shaping the tubular endoplasmic reticulum

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12 December 2020

Blockade of Nogo-66, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein by soluble Nogo-66 receptor promotes axonal sprouting and recovery after spinal injury.

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12 December 2020

The Rho/ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglycans of the CNS glial scar

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12 December 2020

Myelin-associated glycoprotein inhibits microtubule assembly by a Rho-kinase-dependent mechanism

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12 December 2020

Rho GTPases in cell biology

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12 December 2020

Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading

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12 December 2020

Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: the major axon-inhibitory proteoglycan is NG2.

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12 December 2020

Inhibiting glycosaminoglycan chain polymerization decreases the inhibitory activity of astrocyte-derived chondroitin sulfate proteoglycans

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12 December 2020

LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex

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12 December 2020

CRMP-2 binds to tubulin heterodimers to promote microtubule assembly

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12 December 2020

Inactivation of glycogen synthase kinase 3 promotes axonal growth and recovery in the CNS.

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12 December 2020

Increased number of unmyelinated axons in optic nerves of adult mice deficient in the myelin-associated glycoprotein (MAG).

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12 December 2020

Rho kinase inhibition enhances axonal regeneration in the injured CNS.

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12 December 2020

Sprouting and regeneration of lesioned corticospinal tract fibres in the adult rat spinal cord

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12 December 2020

Neurotrophins elevate cAMP to reach a threshold required to overcome inhibition by MAG through extracellular signal-regulated kinase-dependent inhibition of phosphodiesterase.

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12 December 2020

beta1-integrin mediates myelin-associated glycoprotein signaling in neuronal growth cones

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12 December 2020

A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration

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12 December 2020

Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions.

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12 December 2020

The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth.

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12 December 2020

Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury.

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12 December 2020

Netrins and their receptors

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12 December 2020

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12 December 2020

Myelin-associated glycoprotein in myelin and expressed by Schwann cells inhibits axonal regeneration and branching.

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12 December 2020

The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion

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12 December 2020

The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury

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12 December 2020

Arginase I and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro.

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12 December 2020

Rewiring the injured CNS: lessons from the optic nerve

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12 December 2020

Eph/ephrin signaling as a potential therapeutic target after central nervous system injury

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12 December 2020

Delayed Nogo receptor therapy improves recovery from spinal cord contusion

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12 December 2020

Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors

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12 December 2020

A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord

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12 December 2020

BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin

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12 December 2020

Nogo-A, -B, and -C are found on the cell surface and interact together in many different cell types

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12 December 2020

TUC-4b, a novel TUC family variant, regulates neurite outgrowth and associates with vesicles in the growth cone

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12 December 2020

Netrin-1 is a novel myelin-associated inhibitor to axon growth.

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12 December 2020

PirB restricts ocular-dominance plasticity in visual cortex.

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12 December 2020

Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists

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12 December 2020

P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp

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12 December 2020

Identification of CRMP4 as a convergent regulator of axon outgrowth inhibition

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12 December 2020

Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth

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12 December 2020

Siglecs in the immune system

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12 December 2020

Molecular dissection of the myelin-associated glycoprotein receptor complex reveals cell type-specific mechanisms for neurite outgrowth inhibition

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12 December 2020

Assessment of functional recovery and axonal sprouting in oligodendrocyte-myelin glycoprotein (OMgp) null mice after spinal cord injury

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12 December 2020

Regeneration beyond the glial scar

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12 December 2020

A p75(NTR) and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein

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12 December 2020

The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI.

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12 December 2020

Lack of enhanced spinal regeneration in Nogo-deficient mice

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12 December 2020

Nogo-A-deficient mice reveal strain-dependent differences in axonal regeneration.

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12 December 2020

Semaphorins and their receptors in olfactory axon guidance.

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12 December 2020

Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

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12 December 2020

Semaphorins in axon regeneration: developmental guidance molecules gone wrong?

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12 December 2020

Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1

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12 December 2020

Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones

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12 December 2020

Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo

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12 December 2020

Retinal axon growth cone responses to different environmental cues are mediated by different second-messenger systems

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12 December 2020

Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors

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12 December 2020

Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein

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12 December 2020

Promotion of axon regeneration by myelin-associated glycoprotein and Nogo through divergent signals downstream of Gi/G

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12 December 2020

Rho inhibition recruits DCC to the neuronal plasma membrane and enhances axon chemoattraction to netrin 1.

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12 December 2020

Neuropilin and class 3 semaphorins in nervous system regeneration.

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12 December 2020

Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury.

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12 December 2020

The glial scar and central nervous system repair

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12 December 2020

Prior Exposure to Neurotrophins Blocks Inhibition of Axonal Regeneration by MAG and Myelin via a cAMP-Dependent Mechanism

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12 December 2020

Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter.

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12 December 2020

TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration

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12 December 2020

Inhibitor of neurite outgrowth in humans

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12 December 2020

Glial membranes at the node of Ranvier prevent neurite outgrowth

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12 December 2020

Role of semaphorins during axon growth and guidance

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12 December 2020

Suppression of Rho-kinase activity promotes axonal growth on inhibitory CNS substrates

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12 December 2020

Multiple regions of the NG2 proteoglycan inhibit neurite growth and induce growth cone collapse

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12 December 2020

Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1

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12 December 2020

Myosin IIA is required for neurite outgrowth inhibition produced by repulsive guidance molecule

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12 December 2020

Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo.

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12 December 2020

Chondroitin sulfate proteoglycan elevates cytoplasmic calcium in DRG neurons

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12 December 2020

Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse

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12 December 2020

Expression of the oligodendrocyte-myelin glycoprotein by neurons in the mouse central nervous system.

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12 December 2020

Spinal axon regeneration induced by elevation of cyclic AMP.

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12 December 2020

Dying‐back oligodendrogliopathy: A late sequel of myelin‐associated glycoprotein deficiency

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12 December 2020

Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth

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12 December 2020

Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth

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12 December 2020

Gangliosides are neuronal ligands for myelin-associated glycoprotein

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12 December 2020

Current status of experimental cell replacement approaches to spinal cord injury

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12 December 2020

IL-1beta promotes neurite outgrowth by deactivating RhoA via p38 MAPK pathway

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12 December 2020

Response to correspondence: Kim et al., "axon regeneration in young adult mice lacking Nogo-A/B." Neuron 38, 187-199.

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12 December 2020

PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration

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12 December 2020

Neural protein 1B236/myelin-associated glycoprotein (MAG) defines a subgroup of the immunoglobulin superfamily.

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12 December 2020

Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

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12 December 2020

Experience-driven plasticity of visual cortex limited by myelin and Nogo receptor

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12 December 2020

MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth

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12 December 2020

Proteoglycans in the central nervous system: plasticity, regeneration and their stimulation with chondroitinase ABC.

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12 December 2020

The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho.

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12 December 2020

Axon regeneration in young adult mice lacking Nogo-A/B.

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12 December 2020

Myelin-associated inhibitors regulate cofilin phosphorylation and neuronal inhibition through LIM kinase and Slingshot phosphatase.

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12 December 2020

Myelin associated glycoprotein modulates glia-axon contact in vivo

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12 December 2020

Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides.

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12 December 2020

Gangliosides and Nogo receptors independently mediate myelin-associated glycoprotein inhibition of neurite outgrowth in different nerve cells

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12 December 2020

The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate

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12 December 2020

Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate.

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12 December 2020

Oligodendrocyte-myelin glycoprotein (OMgp) is an inhibitor of neurite outgrowth

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12 December 2020

Glial inhibition of CNS axon regeneration

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12 December 2020

Response to: Kim et al., "axon regeneration in young adult mice lacking Nogo-A/B." Neuron 38, 187-199

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12 December 2020

Lack of evidence that myelin-associated glycoprotein is a major inhibitor of axonal regeneration in the CNS.

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12 December 2020

Nogo-66 receptor antagonist peptide promotes axonal regeneration

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12 December 2020

Spinal axon regeneration evoked by replacing two growth cone proteins in adult neurons.

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12 December 2020

Truncated soluble Nogo receptor binds Nogo-66 and blocks inhibition of axon growth by myelin.

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12 December 2020

Widespread expression of netrin-1 by neurons and oligodendrocytes in the adult mammalian spinal cord

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12 December 2020

Inactivation of Rho signaling pathway promotes CNS axon regeneration

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12 December 2020

Chondroitinase ABC promotes functional recovery after spinal cord injury

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12 December 2020

Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo-66 receptor

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12 December 2020

The Nogo-66 receptor homolog NgR2 is a sialic acid-dependent receptor selective for myelin-associated glycoprotein

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12 December 2020

Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway

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12 December 2020

Brain derived versican V2 is a potent inhibitor of axonal growth

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12 December 2020

Rho signaling pathway targeted to promote spinal cord repair.

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12 December 2020

PirB is a functional receptor for myelin inhibitors of axonal regeneration.

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12 December 2020

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.

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12 December 2020

Gangliosides are functional nerve cell ligands for myelin-associated glycoprotein (MAG), an inhibitor of nerve regeneration

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12 December 2020

The Nogo-66 receptor NgR1 is required only for the acute growth cone-collapsing but not the chronic growth-inhibitory actions of myelin inhibitors.

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12 December 2020

NOGO mRNA expression in adult and fetal human and rat nervous tissue and in weight drop injury

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12 December 2020

Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor

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12 December 2020

Multiply myelinated axons in the optic nerve of mice deficient for the myelin-associated glycoprotein

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12 December 2020

EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans

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12 December 2020

Counteracting the Nogo receptor enhances optic nerve regeneration if retinal ganglion cells are in an active growth state.

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12 December 2020

Chondroitin sulfate proteoglycans in neural development and regeneration.

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12 December 2020

The leucine-rich repeat: a versatile binding motif

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12 December 2020

Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration

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12 December 2020

A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors

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12 December 2020

The transcription factor ATF-3 promotes neurite outgrowth.

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12 December 2020

Molecular cloning and primary structure of myelin-associated glycoprotein

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12 December 2020

Nogo-66 receptor prevents raphespinal and rubrospinal axon regeneration and limits functional recovery from spinal cord injury

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12 December 2020

The Nogo-Nogo receptor pathway limits a spectrum of adult CNS axonal growth

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12 December 2020

A role for semaphorins and neuropilins in oligodendrocyte guidance.

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12 December 2020

10.1007/S12035-009-8083-Y

Identifiers

DOI

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21 August 2017

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