Targeted inhibition of Src kinase with dasatinib blocks thyroid cancer growth and metastasis. (Q37597360)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22586301%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Targeted inhibition of Src kinase with dasatinib blocks thyroid cancer growth and metastasis (English)

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1 February 2020

main subject

dasatinib monohydrate

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10

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1 February 2020

author name string

Christine M Chan

1

1 reference

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1 February 2020

Xia Jing

2

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1 February 2020

Laura A Pike

3

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1 February 2020

Qiong Zhou

4

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1 February 2020

Dong-Jun Lim

5

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1 February 2020

Sharon B Sams

6

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1 February 2020

Gregory S Lund

7

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1 February 2020

Vibha Sharma

8

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1 February 2020

Bryan R Haugen

9

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1 February 2020

language of work or name

English

0 references

publication date

14 May 2012

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1 February 2020

published in

Clinical Cancer Research

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1 February 2020

volume

18

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issue

13

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1 February 2020

page(s)

3580-3591

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describes a project that uses

1 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3931551/fullTextXML

inferred from PubMed Central ID database lookup

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Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model

1 September 2018

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Sulforhodamine B colorimetric assay for cytotoxicity screening.

1 September 2018

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Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.

1 September 2018

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Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis

1 September 2018

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Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

1 September 2018

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Overexpression and activation of the tyrosine kinase Src in human pancreatic carcinoma

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22586301

12 December 2020

inferred from PubMed ID database lookup

Refractory thyroid cancer: a paradigm shift in treatment is not far off

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22586301

12 December 2020

inferred from PubMed ID database lookup

C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22586301

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1158/1078-0432.CCR-11-3359

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22586301%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22586301%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

22586301

1 reference