Molecular mechanisms and clinical applications of miR-22 in regulating malignant progression in human cancer (Review). (Q37588086)

21 August 2017

1 reference

19 January 2021

Molecular mechanisms and clinical applications of miR-22 in regulating malignant progression in human cancer (Review). (English)

1 reference

21 August 2017

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3 April 2019

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14 November 2020

neoplasm invasiveness

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19 January 2021

Jingyu Wang

1

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21 August 2017

Yuan Li

2

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21 August 2017

Meiman Ding

3

1 reference

21 August 2017

Honghe Zhang

4

1 reference

21 August 2017

Xiaoming Xu

5

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21 August 2017

Jinlong Tang

6

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21 August 2017

language of work or name

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19 December 2016

1 reference

International Journal of Oncology

21 August 2017

1 February 2017

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3 April 2019

14 November 2020

19 January 2021

4 references

21 August 2017

3 April 2019

14 November 2020

19 January 2021

50

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21 August 2017

2

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21 August 2017

345-355

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Creative Commons Attribution-NonCommercial-NoDerivatives

21 August 2017

3 references

3 April 2019

14 November 2020

19 January 2021

on focus list of Wikimedia project

ScienceSource

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MicroRNA-22 inhibits tumor growth and metastasis in gastric cancer by directly targeting MMP14 and Snail

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miR-22 and miR-29a Are Members of the Androgen Receptor Cistrome Modulating LAMC1 and Mcl-1 in Prostate Cancer.

23 August 2017

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MicroRNA-22 Suppresses DNA Repair and Promotes Genomic Instability through Targeting of MDC1

23 August 2017

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MiR-22-silenced cyclin A expression in colon and liver cancer cells is regulated by bile acid receptor

23 August 2017

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Diagnostic Value of Circulating Extracellular miR-134, miR-185, and miR-22 Levels in Lung Adenocarcinoma-Associated Malignant Pleural Effusion

23 August 2017

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Novel blood-based microRNA biomarker panel for early diagnosis of pancreatic cancer

23 August 2017

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Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis

23 August 2017

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MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination

23 August 2017

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MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling.

23 August 2017

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The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation

23 August 2017

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Reduced expression of miR-22 in gastric cancer is related to clinicopathologic characteristics or patient prognosis

23 August 2017

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Signaling between transforming growth factor β (TGF-β) and transcription factor SNAI2 represses expression of microRNA miR-203 to promote epithelial-mesenchymal transition and tumor metastasis

23 August 2017

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Differentiation-associated microRNAs antagonize the Rb-E2F pathway to restrict proliferation.

23 August 2017

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A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition

23 August 2017

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MicroRNA-22 regulates hypoxia signaling in colon cancer cells

23 August 2017

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miR-22 represses cancer progression by inducing cellular senescence

23 August 2017

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Expression profile of microRNAs in serum: a fingerprint for esophageal squamous cell carcinoma

23 August 2017

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An inhibitory effect of miR-22 on cell migration and invasion in ovarian cancer

23 August 2017

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microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity

23 August 2017

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Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein

23 August 2017

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miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics

23 August 2017

1 reference

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Differentiation-associated miR-22 represses Max expression and inhibits cell cycle progression

23 August 2017

1 reference

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A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer

23 August 2017

1 reference

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MicroRNA profiling of human intrahepatic cholangiocarcinoma cell lines reveals biliary epithelial cell-specific microRNAs

23 August 2017

1 reference

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miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA

23 August 2017

1 reference

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Identification of novel genes coding for small expressed RNAs

23 August 2017

1 reference

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MicroRNA-22 is downregulated in clear cell renal cell carcinoma, and inhibits cell growth, migration and invasion by targeting PTEN.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Molecular mechanisms of microRNAs in regulating epithelial-mesenchymal transitions in human cancers

6 September 2017

1 reference

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Dual Action of miR-125b As a Tumor Suppressor and OncomiR-22 Promotes Prostate Cancer Tumorigenesis.

6 September 2017

1 reference

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MicroRNA-22 functions as a tumor suppressor by targeting SIRT1 in renal cell carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

microRNA-22 acts as a metastasis suppressor by targeting metadherin in gastric cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

miR-22 regulates expression of oncogenic neuro-epithelial transforming gene 1, NET1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

A regulatory loop involving miR-22, Sp1, and c-Myc modulates CD147 expression in breast cancer invasion and metastasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

miR-22 inhibits proliferation and invasion in estrogen receptor α-positive endometrial endometrioid carcinomas cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

MiR-22 is frequently downregulated in medulloblastomas and inhibits cell proliferation via the novel target PAPST1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

MiR-22 suppresses the proliferation and invasion of gastric cancer cells by inhibiting CD151.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Saponins from the roots of Platycodon grandiflorum suppresses TGFβ1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Diallyl disulfide suppresses proliferation and induces apoptosis in human gastric cancer through Wnt-1 signaling pathway by up-regulation of miR-200b and miR-22.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

miR-22 is down-regulated in gastric cancer, and its overexpression inhibits cell migration and invasion via targeting transcription factor Sp1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

miRNA-22 suppresses colon cancer cell migration and invasion by inhibiting the expression of T-cell lymphoma invasion and metastasis 1 and matrix metalloproteinases 2 and 9.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Multiple microRNAs induced by Cdx1 suppress Cdx2 in human colorectal tumour cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Tumor suppressor miR-22 suppresses lung cancer cell progression through post-transcriptional regulation of ErbB3.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Control of EVI-1 oncogene expression in metastatic breast cancer cells through microRNA miR-22.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

miR-22 promotes HBV-related hepatocellular carcinoma development in males

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Serum microRNA panels as potential biomarkers for early detection of hepatocellular carcinoma on top of HCV infection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

TET2 expression level and 5-hydroxymethylcytosine are decreased in refractory cytopenia of childhood

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

miR-22 is down-regulated in esophageal squamous cell carcinoma and inhibits cell migration and invasion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

MicroRNA hsa-miR-4674 in Hemolysis-Free Blood Plasma Is Associated with Distant Metastases of Prostatic Cancer.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Activation of the PI3K/AKT pathway by microRNA-22 results in CLL B-cell proliferation.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Circulating miR-22, miR-24 and miR-34a as novel predictive biomarkers to pemetrexed-based chemotherapy in advanced non-small cell lung cancer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

MicroRNA-22 is down-regulated in hepatitis B virus-related hepatocellular carcinoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Effect of curcumin on miRNA expression in human Y79 retinoblastoma cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Clinical significance of miR-22 expression in patients with colorectal cancer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

Tumor suppressor miR-22 determines p53-dependent cellular fate through post-transcriptional regulation of p21.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5238783

EDD1 predicts prognosis and regulates gastric cancer growth in vitro and in vivo via miR-22

1 September 2018

1 reference

12 December 2020

miR-22 inhibits osteosarcoma cell proliferation and migration by targeting HMGB1 and inhibiting HMGB1-mediated autophagy

1 reference

12 December 2020

Overexpression of miR-22 reverses paclitaxel-induced chemoresistance through activation of PTEN signaling in p53-mutated colon cancer cells

1 reference

12 December 2020

miR-22 as a prognostic factor targets glucose transporter protein type 1 in breast cancer

1 reference

12 December 2020

Integrated analysis of gene copy number, copy neutral LOH, and microRNA profiles in adult acute lymphoblastic leukemia

1 reference

12 December 2020

MiR-22 regulates 5-FU sensitivity by inhibiting autophagy and promoting apoptosis in colorectal cancer cells

1 reference

12 December 2020

microRNA-22 downregulation of galectin-9 influences lymphocyte apoptosis and tumor cell proliferation in liver cancer

1 reference

12 December 2020

Identifiers

DOI

10.3892/IJO.2016.3811

1 reference

21 August 2017

1 reference

21 August 2017

1 reference