DNA damage related to increased hydrogen peroxide generation by hypolipidemic drug-induced liver peroxisomes (Q37580375)

21 August 2017

DNA damage related to increased hydrogen peroxide generation by hypolipidemic drug-induced liver peroxisomes (English)

1 reference

21 August 2017

0 references

W. E. Fahl

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6096860

4 August 2023

N. D. Lalwani

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6096860

4 August 2023

T. Watanabe

3

1 reference

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4 August 2023

S. K. Goel

4

1 reference

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4 August 2023

J. K. Reddy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6096860

4 August 2023

language of work or name

English

0 references

publication date

1 December 1984

1 reference

PMCID

392245

full work available at URL

21 August 2017

https://europepmc.org/articles/PMC392245

1 reference

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https://europepmc.org/articles/PMC392245?pdf=render

4 August 2023

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6096860

https://pnas.org/doi/pdf/10.1073/pnas.81.24.7827

4 August 2023

1 reference

Crossref

DOI

10.1073/PNAS.81.24.7827

https://api.crossref.org/works/10.1073/PNAS.81.24.7827

Proceedings of the National Academy of Sciences of the United States of America

4 August 2023

published in

1 reference

21 August 2017

81

1 reference

21 August 2017

7827-7830

1 reference

21 August 2017

24

1 reference

Purification and properties of acyl-CoA oxidase from rat liver

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

5,6-Saturated thymine lesions in DNA: production by ultraviolet light or hydrogen peroxide

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Mutagenicity of oxygen free radicals

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Dimethyl sulfoxide prevents DNA nicking mediated by ionizing radiation or iron/hydrogen peroxide-generated hydroxyl radical

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

A new Salmonella tester strain (TA102) with A X T base pairs at the site of mutation detects oxidative mutagens

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Induction of hepatic peroxisome proliferation in nonrodent species, including primates

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

The kinetics of degradation of DNA and RNA by H2O2

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Selective extraction of polyoma DNA from infected mouse cell cultures

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

The Biology of Oxygen Radicals

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Hydroperoxide metabolism in mammalian organs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Hepatic and renal effects of peroxisome proliferators: biological implications

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Enhancing effect of hydrogen peroxide upon duodenal and upper jejunal carcinogenesis in rats.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Carcinogen testing: current problems and new approaches.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Evaluation of selected hypolipidemic agents for the induction of peroxisomal enzymes and peroxisome proliferation in the rat liver.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Properties of hypolipidemic peroxisome proliferators in the lymphocyte [3H]thymidine and Salmonella mutagenesis assays.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Induction of peroxisomal enzymes in livers of neonatal rats exposed to lactating mothers treated with hypolipidaemic drugs. Role of drug metabolite transfer in milk

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Reversible alteration of hepatic messenger RNA species for peroxisomal and non-peroxisomal proteins induced by the hypolipidaemic drug Wy-14,643.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Tissue fractionation studies. 17. Intracellular distribution of monoamine oxidase, aspartate aminotransferase, alanine aminotransferase, D-amino acid oxidase and catalase in rat-liver tissue

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Glycerolipid biosynthesis in peroxisomes via the acyl dihydroxyacetone phosphate pathway

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Chemical carcinogens without mutagenic activity: peroxisome proliferators as a prototype.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=392245

Hepatic microsomal ethanol oxidation. Hydrogen peroxide formation and the role of catalase

1 September 2018

1 reference

12 December 2020

Diffusion effects in the metabolism of hydrogen peroxide by rat liver peroxisomes

1 reference

12 December 2020

Hepatic Peroxisome Proliferation: Induction by Two Novel Compounds Structurally Unrelated to Clofibrate

1 reference

12 December 2020

Characterization of a Cell-Lethal Product from the Photooxidation of Tryptophan: Hydrogen Peroxide

1 reference

12 December 2020

Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens

1 reference

12 December 2020

Induction of single-strand DNA breaks in human cells by H2O2 formed in near-uv (black light) irradiated medium

1 reference

12 December 2020

The relative effectiveness of .OH, H2O2, O2-, and reducing free radicals in causing damage to biomembranes. A study of radiation damage to erythrocyte ghosts using selective free radical scavengers

1 reference

12 December 2020

Lack of covalent binding to rat liver DNA of the hypolipidemic drugs clofibrate and fenofibrate

1 reference

12 December 2020

DNA strand scission by enzymically generated oxygen radicals

1 reference

12 December 2020

Hydrogen peroxide kills Staphylococcus aureus by reacting with staphylococcal iron to form hydroxyl radical

1 reference

12 December 2020

Comparison of the effects of hydrogen peroxide and X-ray irradiation on toxicity, mutation, and DNA damage/repair in mammalian cells (V-79)

1 reference

12 December 2020

Chemical carcinogenesis

1 reference

12 December 2020

Excessive accumulation of autofluorescent lipofuscin in the liver during hepatocarcinogenesis by methyl clofenapate and other hypolipidemic peroxisome proliferators

1 reference

12 December 2020

Cell-free synthesis of the enzymes of peroxisomal beta-oxidation

1 reference

12 December 2020

Noninhibitory effect of antioxidants ethoxyquin, 2(3)-tert-butyl-4-hydroxyanisole and 3,5-di-tert-butyl-4-hydroxytoluene on hepatic peroxisome proliferation and peroxisomal fatty acid beta-oxidation induced by a hypolipidemic agent in rats

1 reference

12 December 2020

Chemicals and cancer: initiation and promotion

1 reference

12 December 2020

NATURE OF THE HEPATOMEGALIC EFFECT PRODUCED BY ETHYL-CHLOROPHENOXY-ISOBUTYRATE IN THE RAT

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.81.24.7827

1 reference

21 August 2017

0 references

1 reference

21 August 2017

1 reference

PMCID

392245