The European Union's REACH regulation: a review of its history and requirements (Q37570526)

21 August 2017

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title

The European Union's REACH regulation: a review of its history and requirements (English)

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21 August 2017

E Spencer Williams

1

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21 August 2017

Julie Panko

series ordinal

2

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21 August 2017

Dennis J Paustenbach

series ordinal

3

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21 August 2017

language of work or name

English

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publication date

1 January 2009

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Critical Reviews in Toxicology

21 August 2017

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21 August 2017

39

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21 August 2017

7

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21 August 2017

553-575

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Integrated testing and intelligent assessment-new challenges under REACH.

21 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Application of in vitro neurotoxicity testing for regulatory purposes: Symposium III summary and research needs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

German Environmental Survey (GerES): human biomonitoring as a tool to identify exposure pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Exposure-triggered reproductive toxicity testing under the REACH legislation: a proposal to define significant/relevant exposure.

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440903036056

Brominated flame retardants: cause for concern?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Perchlorate exposure of the US Population, 2001-2002.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

The costs of REACH. REACH is largely welcomed, but the requirement to test existing chemicals for adverse effects is not good news for all.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

A toxicologically based weight-of-evidence methodology for the relative ranking of chemicals of endocrine disruption potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Polyfluoroalkyl chemicals in the U.S. population: data from the National Health and Nutrition Examination Survey (NHANES) 2003-2004 and comparisons with NHANES 1999-2000

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Urinary concentrations of triclosan in the U.S. population: 2003-2004

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440903036056

The ECVAM International Validation Study on In Vitro Tests for Skin Corrosivity. 2. Results and Evaluation by the Management Team.

21 January 2018

1 reference

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Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey of the United States population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Regulatory assessment of chemicals within OECD member countries, EU and in Russia.

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440903036056

Concept of REACH and impact on evaluation of chemicals

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440903036056

Testing REACH draft technical guidance notes for conducting chemical safety assessments-the experience of a downstream user of a preparation

21 January 2018

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Derivation of predicted No-effect concentrations for lindane, 3, 4-dichloroaniline, atrazine, and copper.

21 January 2018

1 reference

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Hormesis in precautionary regulatory culture: models preferences and the advancement of science

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Animal testing and alternative approaches for the human health risk assessment under the proposed new European chemicals regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Modeling framework for human exposure assessment

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440903036056

A systematic approach for evaluating the quality of experimental toxicological and ecotoxicological data

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440903036056

The precautionary principle in environmental science

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440903036056

The threshold of toxicological concern concept in risk assessment

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440903036056

Structure-based thresholds of toxicological concern (TTC): guidance for application to substances present at low levels in the diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

REACH—The New European Chemicals Law

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Perfluoroalkyl acids: a review of monitoring and toxicological findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Integrating process safety with molecular modeling-based risk assessment of chemicals within the REACH regulatory framework: benefits and future challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

The ECETOC approach to targeted risk assessment; lessons and experiences relevant to REACH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

EU risk assessment: science and policy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

The Threshold of Toxicological Concern (TTC) in risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Accuracy, comprehensibility, and use of material safety data sheets: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

21 January 2018

EASEing into the future

1 reference

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Biomonitoring and biomarkers: exposure assessment will never be the same

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440903036056

The precautionary principle should not be used as a basis for decision-making. Talking point on the precautionary principle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

An analysis of the proposed REACH regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Global harmonisation of classification and labelling of hazardous chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Precaution and analysis: two sides of the same coin? Introduction to talking point on the precautionary principle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

The European Commission's White Paper “Strategy for a Future Chemicals Policy”: A Review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Workers' understanding of chemical risks: electroplating case study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Effect thresholds and 'adequate control' of risks: The fatal flaws in the EU council's position on authorisation within REACH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Twenty years of the German Environmental Survey (GerES): human biomonitoring--temporal and spatial (West Germany/East Germany) differences in population exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

The challenge of reproductive and developmental toxicology under REACH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

Environmental risk assessment of musk ketone and musk xylene in The Netherlands in accordance with the EU-TGD.

21 January 2018

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The U.S. experience in promoting sustainable chemistry

21 January 2018

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Tools for regulatory assessment of occupational exposure: development and challenges

21 January 2018

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REACH: next step to a sound chemicals management

21 January 2018

1 reference

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RISKOFDERM: Risk Assessment of Occupational Dermal Exposure to Chemicals. An Introduction to a Series of Papers on the Development of a Toolkit

21 January 2018

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Global government applications of analogues, SARs and QSARs to predict aquatic toxicity, chemical or physical properties, environmental fate parameters and health effects of organic chemicals

21 January 2018

1 reference

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Assessing and managing the hazards and risks of chemicals in the real world--the role of the EU's REACH proposal in future regulation of chemicals

21 January 2018

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Weight of evidence: a review of concept and methods

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440903036056

Occurrence and effects of tire wear particles in the environment--a critical review and an initial risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

The development of the globally harmonized system (GHS) of classification and labelling of hazardous chemicals

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440903036056

Searching fee and non-fee toxicology information resources: an overview of selected databases.

21 January 2018

1 reference

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Weight of the Evidence Evaluation of Low-Dose Reproductive and Developmental Effects of Bisphenol A

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440903036056

10.1080/10408440903036056

21 January 2018

Identifiers

DOI

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21 August 2017

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