A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease (Q37568754)

21 August 2017

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease (English)

1 reference

21 August 2017

0 references

7

1 reference

21 August 2017

39

1 reference

21 August 2017

68

1 reference

21 August 2017

70

1 reference

21 August 2017

78

1 reference

21 August 2017

Yvonne T van der Schouw

103

1 reference

21 August 2017

121

1 reference

21 August 2017

131

1 reference

21 August 2017

133

1 reference

21 August 2017

143

1 reference

21 August 2017

Martina Müller-Nurasyid

76

Martina Müller-Nurasyid

0 references

Heribert Schunkert

137

Heribert Schunkert

0 references

Eric Boerwinkle

35

Eric Boerwinkle

0 references

Inês Barroso

29

Inês Barroso

0 references

Johanna Kuusisto

69

Johanna Kuusisto

0 references

Claudia Langenberg

129

Claudia Langenberg

0 references

Kenneth Muir

75

Kenneth Muir

1 reference

21 August 2017

66

Zsofia Kote-Jarai

1 reference

21 August 2017

Børge G. Nordestgaard

81

Børge G Nordestgaard

0 references

Heiner Boeing

34

Heiner Boeing

1 reference

21 August 2017

28

Aurelio Barricarte

0 references

Marcel den Hoed

45

Marcel den Hoed

1 reference

21 August 2017

Ailith Pirie

19

0 references

Sarah J Bowden

Sarah Bowden

38

0 references

Jukka Kontto

Jukka Kontto

65

0 references

Sven J van der Lee

Sven J van der Lee

20

0 references

Jennifer Wessel

Jennifer Wessel

15

0 references

Tibor V. Varga

Tibor V Varga

10

0 references

Adam S. Butterworth

Adam S Butterworth

117

0 references

Kyriaki Michailidou

Kyriaki Michailidou

18

0 references

Francesco Gianfagna

Francesco Gianfagna

54

0 references

Janet A Dunn

Janet A Dunn

46

0 references

Jennifer A Smith

Jennifer A Smith

98

0 references

Nita G. Forouhi

Nita G Forouhi

53

0 references

Helena Earl

Helena M Earl

47

0 references

Laufey T. Amundadottir

Laufey T Amundadottir

115

0 references

Marit E. Jørgensen

Marit E Jørgensen

59

0 references

Josée Dupuis

Josée Dupuis

118

0 references

Sara Grioni

Sara Grioni

56

0 references

Paul W. Franks

Paul W Franks

122

0 references

Domenico Palli

Domenico Palli

83

0 references

Carlotta Sacerdote

Carlotta Sacerdote

91

0 references

Annette Peters

Annette Peters

87

0 references

Jean Ferrières

Jean Ferrieres

50

0 references

Torben Hansen

Torben Hansen

124

0 references

Philippe Amouyel

Philippe Amouyel

23

0 references

Torben Jørgensen

Torben Jørgensen

126

0 references

Oluf Borbye Pedersen

Oluf Pedersen

132

0 references

Karen L Mohlke

73

Karen L Mohlke

1 reference

21 August 2017

134

Jerome I Rotter

1 reference

21 August 2017

86

Markus Perola

1 reference

21 August 2017

92

Veikko Salomaa

1 reference

21 August 2017

Rosalind A Eeles

120

0 references

Stephen O'Rahilly

Stephen O'Rahilly

139

0 references

Rudolf Kaaks

61

Rudolf Kaaks

1 reference

21 August 2017

101

Rosario Tumino

1 reference

21 August 2017

Mark I McCarthy

130

0 references

Nilesh Samani

136

Nilesh J Samani

1 reference

21 August 2017

84

Salvatore Panico

1 reference

21 August 2017

119

Douglas F Easton

1 reference

21 August 2017

149

Nicholas J Wareham

1 reference

21 August 2017

128

Markku Laakso

1 reference

21 August 2017

33

Michael Boehnke

1 reference

21 August 2017

51

Thomas Foltynie

1 reference

21 August 2017

135

Danish Saleheen

1 reference

21 August 2017

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Naveed Sattar

1 reference

21 August 2017

100

Stella Trompet

1 reference

21 August 2017

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Sekar Kathiresan

1 reference

21 August 2017

147

James B Meigs

1 reference

21 August 2017

11

Hanieh Yaghootkar

1 reference

21 August 2017

97

Nadia Slimani

1 reference

21 August 2017

12

Jian'an Luan

1 reference

21 August 2017

138

Peter Vollenweider

1 reference

21 August 2017

104

Jarmo Virtamo

1 reference

21 August 2017

31

Joshua C Bis

1 reference

21 August 2017

36

Ingrid B Borecki

1 reference

21 August 2017

123

Timothy M Frayling

1 reference

21 August 2017

77

Patricia B Munroe

1 reference

21 August 2017

49

Ele Ferrannini

1 reference

21 August 2017

127

Jaspal Kooner

1 reference

21 August 2017

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Mark O Goodarzi

1 reference

21 August 2017

32

Stefan Blankenberg

1 reference

21 August 2017

150

Dawn M Waterworth

1 reference

21 August 2017

60

J Wouter Jukema

1 reference

21 August 2017

144

John Danesh

1 reference

21 August 2017

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L Adrienne Cupples

1 reference

21 August 2017

79

Sune F Nielsen

1 reference

21 August 2017

125

Joanna M M Howson

1 reference

21 August 2017

85

Gina M Peloso

1 reference

21 August 2017

48

Georg B Ehret

1 reference

21 August 2017

1

Robert A Scott

1 reference

21 August 2017

62

Frank Kee

1 reference

21 August 2017

25

Dominique Arveiler

1 reference

21 August 2017

5

Praveen Surendran

1 reference

21 August 2017

2

Daniel F Freitag

1 reference

21 August 2017

40

Muriel Caslake

1 reference

21 August 2017

67

Aldi T Kraja

1 reference

21 August 2017

140

CHARGE consortium

1 reference

21 August 2017

37

Jette Bork-Jensen

1 reference

21 August 2017

90

Olov Rolandsson

1 reference

21 August 2017

27

Beverley Balkau

1 reference

21 August 2017

63

Nicola D Kerrison

1 reference

21 August 2017

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Stephen J Sharp

1 reference

21 August 2017

Christopher J Gillson

21

Christopher Gillson

1 reference

21 August 2017

4

Audrey Y Chu

1 reference

21 August 2017

24

Larraitz Arriola

1 reference

21 August 2017

99

Deborah J Thompson

1 reference

21 August 2017

148

Margaret G Ehm

1 reference

21 August 2017

116

Jennifer L Aponte

1 reference

21 August 2017

17

Nisa Maruthur

1 reference

21 August 2017

58

Jan-Håkan Jansson

1 reference

21 August 2017

8

Alena Stancáková

1 reference

21 August 2017

74

Andrew P Morris

1 reference

21 August 2017

52

Ian Ford

1 reference

21 August 2017

Li Li

3

1 reference

21 August 2017

Robin Young

6

1 reference

21 August 2017

Yuning Chen

9

1 reference

21 August 2017

Jing Hua Zhao

13

1 reference

21 August 2017

Sara M Willems

14

1 reference

21 August 2017

Shuai Wang

16

1 reference

21 August 2017

Ali Amin Al Olama

22

1 reference

21 August 2017

Iciar Aviles-Olmos

26

1 reference

21 August 2017

Sara Benlloch Garcia

30

1 reference

21 August 2017

CVD50 consortium

41

1 reference

21 August 2017

Carlos Cruchaga

43

1 reference

21 August 2017

Jacek Czajkowski

44

1 reference

21 August 2017

Carlos Gonzalez

55

1 reference

21 August 2017

Louise Hiller

57

1 reference

21 August 2017

Timothy J Key

64

1 reference

21 August 2017

Chunyu Liu

71

1 reference

21 August 2017

Gaëlle Marenne

72

1 reference

21 August 2017

Peter M Nilsson

80

1 reference

21 August 2017

Chris J Packard

82

1 reference

21 August 2017

Christopher J Poole

88

1 reference

21 August 2017

J Ramón Quirós

89

1 reference

21 August 2017

María-José Sánchez

93

1 reference

21 August 2017

Rebecca Sims

96

1 reference

21 August 2017

Daphne L van der A

102

1 reference

21 August 2017

Mark Walker

105

1 reference

21 August 2017

Klaudia Walter

106

1 reference

21 August 2017

GERAD_EC Consortium

107

1 reference

21 August 2017

Neurology Working Group of the Cohorts for Heart

108

1 reference

21 August 2017

Aging Research in Genomic Epidemiology (CHARGE)

109

1 reference

21 August 2017

Alzheimer’s Disease Genetics Consortium

110

1 reference

21 August 2017

Pancreatic Cancer Cohort Consortium

111

1 reference

21 August 2017

European Prospective Investigation into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD)

112

1 reference

21 August 2017

EPIC-InterAct

113

1 reference

21 August 2017

Jean E Abraham

114

1 reference

21 August 2017

CHD Exome+ Consortium

141

1 reference

21 August 2017

CARDIOGRAM Exome Consortium

142

1 reference

21 August 2017

language of work or name

English

0 references

publication date

1 June 2016

1 reference

Science Translational Medicine

21 August 2017

1 reference

21 August 2017

8

1 reference

21 August 2017

341ra76

1 reference

21 August 2017

341

1 reference

Analysis of protein-coding genetic variation in 60,706 humans

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

The support of human genetic evidence for approved drug indications

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Inactivating mutations in NPC1L1 and protection from coronary heart disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Pharmacodynamics of the glucagon-like peptide-1 receptor agonist lixisenatide in Japanese and Caucasian patients with type 2 diabetes mellitus poorly controlled on sulphonylureas with/without metformin

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Tolerability of nausea and vomiting and associations with weight loss in a randomized trial of liraglutide in obese, non-diabetic adults

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Exenatide and the treatment of patients with Parkinson's disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Adding once-daily lixisenatide for type 2 diabetes inadequately controlled by established basal insulin: a 24-week, randomized, placebo-controlled comparison (GetGoal-L)

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Adding once-daily lixisenatide for type 2 diabetes inadequately controlled with newly initiated and continuously titrated basal insulin glargine: a 24-week, randomized, placebo-controlled study (GetGoal-Duo 1).

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Efficacy and safety of lixisenatide once-daily morning or evening injections in type 2 diabetes inadequately controlled on metformin (GetGoal-M).

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

The effect of glucagon-like peptide-1 receptor agonist therapy on body mass index in adolescents with severe obesity: a randomized, placebo-controlled, clinical trial

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Evolution and functional impact of rare coding variation from deep sequencing of human exomes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal-L-Asia).

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

What makes UK Biobank special?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Efficacy and safety of the once-daily GLP-1 receptor agonist lixisenatide in monotherapy: a randomized, double-blind, placebo-controlled trial in patients with type 2 diabetes (GetGoal-Mono)

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Blood pressure loci identified with a gene-centric array

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Short-term exenatide treatment leads to significant weight loss in a subset of obese women without diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Polymorphism and ligand dependent changes in human glucagon-like peptide-1 receptor (GLP-1R) function: allosteric rescue of loss of function mutation.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Diabetes mellitus, fasting glucose, and risk of cause-specific death

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Dose-dependent effects of the once-daily GLP-1 receptor agonist lixisenatide in patients with Type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled trial

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Glucagon-like peptide-1 receptor knockout mice are protected from high-fat diet-induced insulin resistance

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effects of exenatide combined with lifestyle modification in patients with type 2 diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effects of exenatide and lifestyle modification on body weight and glucose tolerance in obese subjects with and without pre-diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effects of exenatide plus rosiglitazone on beta-cell function and insulin sensitivity in subjects with type 2 diabetes on metformin

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Pharmacological characterization of human incretin receptor missense variants

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): a randomised controlled trial

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Incretin-based therapies for type 2 diabetes mellitus

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

The ADDITION-Cambridge trial protocol: a cluster -- randomised controlled trial of screening for type 2 diabetes and intensive treatment for screen-detected patients

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD-1 SU)

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met+TZD).

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Genetically elevated C-reactive protein and ischemic vascular disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Case-cohort design in practice - experiences from the MORGAM Project

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

The NCBI dbGaP database of genotypes and phenotypes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Lack of support for the association between GAD2 polymorphisms and severe human obesity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

MORGAM (an international pooling of cardiovascular cohorts).

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Diet and cancer--the European Prospective Investigation into Cancer and Nutrition.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Factors of risk in the development of coronary heart disease--six year follow-up experience. The Framingham Study

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Determinants of the effectiveness of glucagon-like peptide-1 in type 2 diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Cardiovascular actions of incretin-based therapies

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

A systematic review and meta-analysis of the efficacy of lixisenatide in the treatment of patients with type 2 diabetes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Validating therapeutic targets through human genetics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Efficacy, safety, and tolerability of exenatide once weekly in patients with type 2 diabetes mellitus: an integrated analysis of the DURATION trials.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Exenatide as a novel weight loss modality in patients without diabetes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Circulating 25-hydroxyvitamin D concentration and the risk of type 2 diabetes: results from the European Prospective Investigation into Cancer (EPIC)-Norfolk cohort and updated meta-analysis of prospective studies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

The effect of glucagon-like peptide 1 on cardiovascular risk

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

The EGIR-RISC STUDY (The European group for the study of insulin resistance: relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and objectives

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effect of exenatide on heart rate and blood pressure in subjects with type 2 diabetes mellitus: a double-blind, placebo-controlled, randomized pilot study

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Incidence of Type 2 diabetes in England and its association with baseline impaired fasting glucose: the Ely study 1990-2000.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome

14 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

28 September 2017

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD3744

Recent explosive human population growth has resulted in an excess of rare genetic variants

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Deep resequencing reveals excess rare recent variants consistent with explosive population growth

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

A placebo-controlled trial of exenatide twice-daily added to thiazolidinediones alone or in combination with metformin

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Lixisenatide treatment improves glycaemic control in Asian patients with type 2 diabetes mellitus inadequately controlled on metformin with or without sulfonylurea: a randomized, double-blind, placebo-controlled, 24-week trial (GetGoal-M-Asia).

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Efficacy and safety of lixisenatide once daily vs. placebo in people with Type 2 diabetes insufficiently controlled on metformin (GetGoal-F1).

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Variation in inflammatory markers and glycemic parameters after 12 months of exenatide plus metformin treatment compared with metformin alone: a randomized placebo-controlled trial.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effects of lixisenatide once daily on gastric emptying in type 2 diabetes--relationship to postprandial glycemia

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Efficacy and safety of lixisenatide once daily versus placebo in type 2 diabetes insufficiently controlled on pioglitazone (GetGoal-P).

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Exenatide plus metformin compared with metformin alone on β-cell function in patients with Type 2 diabetes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Association between birth weight and visceral fat in adults

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Exenatide exhibits dose-dependent effects on glycemic control over 12 weeks in Japanese patients with suboptimally controlled type 2 diabetes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Efficacy and safety of exenatide in patients of Asian descent with type 2 diabetes inadequately controlled with metformin or metformin and a sulphonylurea

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Efficacy and tolerability of exenatide monotherapy over 24 weeks in antidiabetic drug-naive patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, parallel-group study

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Dose-dependent improvement in glycemia with once-daily liraglutide without hypoglycemia or weight gain: A double-blind, randomized, controlled trial in Japanese patients with type 2 diabetes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Comparison of single and combined treatment with exenatide and metformin on menstrual cyclicity in overweight women with polycystic ovary syndrome

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 diabetes: a randomized trial.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

EPIC-Heart: the cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000 middle-aged participants from 10 European countries.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project).

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Anthropometric, lifestyle and metabolic determinants of resting heart rate. A population study

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

Cardiovascular disease and diabetes in the Northern Sweden Health and Disease Study Cohort - evaluation of risk factors and their interactions

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

EPIC-Norfolk: study design and characteristics of the cohort. European Prospective Investigation of Cancer

2 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219001

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

2 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD3744

Analysis of protein-coding genetic variation in 60,706 humans

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD3744

Addition of liraglutide in patients with Type 2 diabetes well controlled on metformin monotherapy improves several markers of vascular function

21 January 2018

1 reference

12 December 2020

Use of Twice-Daily Exenatide in Basal Insulin–Treated Patients With Type 2 Diabetes

1 reference

12 December 2020

Exenatide and rare adverse events

1 reference

12 December 2020

Nonfasting Triglycerides and Risk of Myocardial Infarction, Ischemic Heart Disease, and Death in Men and Women

1 reference

12 December 2020

Beneficial effects of once-daily lixisenatide on overall and postprandial glycemic levels without significant excess of hypoglycemia in type 2 diabetes inadequately controlled on a sulfonylurea with or without metformin (GetGoal-S)

1 reference

12 December 2020

10.1126/SCITRANSLMED.AAD3744

Identifiers

DOI

1 reference

21 August 2017

1 reference

21 August 2017

1 reference