Chinchilla as a robust, reproducible and polymicrobial model of otitis media and its prevention (Q37559643)

21 August 2017

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title

Chinchilla as a robust, reproducible and polymicrobial model of otitis media and its prevention (English)

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21 August 2017

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Lauren O Bakaletz

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21 August 2017

1 August 2009

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Expert Review of Vaccines

21 August 2017

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21 August 2017

8

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21 August 2017

8

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21 August 2017

1063-1082

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Report of a workshop on respiratory viral infections: epidemiology, diagnosis, treatment, and prevention

21 August 2017

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Microbial synergism in human infections (first of two parts)

21 January 2018

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Management of otitis media with effusion in young children

21 January 2018

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Trends in otitis media among children in the United States

21 January 2018

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Compared to placebo, long-term antibiotics resolve otitis media with effusion (OME) and prevent acute otitis media with perforation (AOMwiP) in a high-risk population: a randomized controlled trial

21 January 2018

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Evidence behind the WHO guidelines: hospital care for children: what is the most effective antibiotic regime for chronic suppurative otitis media in children?

21 January 2018

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Otitis media in infancy and intellectual ability, school achievement, speech, and language at age 7 years. Greater Boston Otitis Media Study Group.

21 January 2018

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Overall cost in the treatment of otitis media

21 January 2018

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Respiratory viral infection predisposing for bacterial disease: a concise review

21 January 2018

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Influenza virus and rhinovirus-related otitis media: potential for antiviral intervention

21 January 2018

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The role of respiratory viruses in otitis media

21 January 2018

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Role of viruses in the pathogenesis of acute otitis media

21 January 2018

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Otitis media in 2253 Pittsburgh-area infants: prevalence and risk factors during the first two years of life

21 January 2018

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Epidemiology of otitis media onset by six months of age.

21 January 2018

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Arginine or nitrate enhances antibiotic susceptibility of Pseudomonas aeruginosa in biofilms

21 January 2018

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Oxygen limitation contributes to antibiotic tolerance of Pseudomonas aeruginosa in biofilms.

21 January 2018

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Contributions of antibiotic penetration, oxygen limitation, and low metabolic activity to tolerance of Pseudomonas aeruginosa biofilms to ciprofloxacin and tobramycin

21 January 2018

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Intercellular adhesion and biocide resistance in nontypeable Haemophilus influenzae biofilms

21 January 2018

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Evidence of bacterial metabolic activity in culture-negative otitis media with effusion

21 January 2018

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Phenotypic characterization of Streptococcus pneumoniae biofilm development

21 January 2018

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Identification of biofilm proteins in non-typeable Haemophilus Influenzae

21 January 2018

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Biofilm formation by nontypeable Haemophilus influenzae: strain variability, outer membrane antigen expression and role of pili

21 January 2018

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Biofilm formation by Moraxella catarrhalis in vitro: roles of the UspA1 adhesin and the Hag hemagglutinin

21 January 2018

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Haemophilus influenzae forms biofilms on airway epithelia: implications in cystic fibrosis

21 January 2018

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Biofilm growth increases phosphorylcholine content and decreases potency of nontypeable Haemophilus influenzae endotoxins

21 January 2018

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Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media

21 January 2018

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Haemophilus influenzae luxS mutants form a biofilm and have increased virulence

21 January 2018

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Mucosal biofilm formation on middle-ear mucosa in the chinchilla model of otitis media

21 January 2018

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Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media

21 January 2018

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Phosphorylcholine decreases early inflammation and promotes the establishment of stable biofilm communities of nontypeable Haemophilus influenzae strain 86-028NP in a chinchilla model of otitis media

21 January 2018

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Role of sialic acid and complex carbohydrate biosynthesis in biofilm formation by nontypeable Haemophilus influenzae in the chinchilla middle ear.

21 January 2018

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Sialylation of lipooligosaccharides promotes biofilm formation by nontypeable Haemophilus influenzae

21 January 2018

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Survival of bacterial biofilms within neutrophil extracellular traps promotes nontypeable Haemophilus influenzae persistence in the chinchilla model for otitis media.

21 January 2018

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Streptococcus pneumoniae forms surface-attached communities in the middle ear of experimentally infected chinchillas

21 January 2018

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Distribution of bacterial proteins in biofilms formed by non-typeable Haemophilus influenzae

21 January 2018

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Biofilms formed by nontypeable Haemophilus influenzae in vivo contain both double-stranded DNA and type IV pilin protein

21 January 2018

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Phosphorylcholine expression by nontypeable Haemophilus influenzae correlates with maturation of biofilm communities in vitro and in vivo

21 January 2018

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Nontypeable Haemophilus influenzae strain 2019 produces a biofilm containing N-acetylneuraminic acid that may mimic sialylated O-linked glycans

21 January 2018

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Lipooligosaccharides containing phosphorylcholine delay pulmonary clearance of nontypeable Haemophilus influenzae

21 January 2018

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Multiple mechanisms for choline transport and utilization in Haemophilus influenzae

21 January 2018

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Duplicate copies of lic1 direct the addition of multiple phosphocholine residues in the lipopolysaccharide of Haemophilus influenzae

21 January 2018

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Binding of the non-typeable Haemophilus influenzae lipooligosaccharide to the PAF receptor initiates host cell signalling.

21 January 2018

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Haemophilus influenzae biofilms: hypothesis or fact?

21 January 2018

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Otitis media: the chinchilla model

21 January 2018

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Visual and nonvisual auditory systems in mammals. Anatomical evidence indicates two kinds of auditory pathways and suggests two kinds of hearing in mammals

21 January 2018

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Temporal summation of acoustic signals by the chinchilla.

21 January 2018

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Audibility Curve of the Chinchilla

21 January 2018

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Experimental Otitis Media Due to Streptococcus pneumoniae: Immunopathogenic Response in the Chinchilla

21 January 2018

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Modeling adenovirus type 1-induced otitis media in the chinchilla: effect on ciliary activity and fluid transport function of eustachian tube mucosal epithelium

21 January 2018

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Chinchilla and murine models of upper respiratory tract infections with respiratory syncytial virus

21 January 2018

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Cytological and histological changes in the middle ear after inoculation of influenza A virus

21 January 2018

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Vaccination against middle-ear bacterial and viral pathogens.

21 January 2018

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Kinetics of the ascension of NTHi from the nasopharynx to the middle ear coincident with adenovirus-induced compromise in the chinchilla.

21 January 2018

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Bacterial sinusitis and otitis media following influenza virus infection in ferrets

21 January 2018

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Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness

21 January 2018

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Viral potentiation of bacterial superinfection of the respiratory tract

21 January 2018

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Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral species- and cell type-dependent manner.

21 January 2018

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IFN-gamma amplifies NFkappaB-dependent Neisseria meningitidis invasion of epithelial cells via specific upregulation of CEA-related cell adhesion molecule 1.

21 January 2018

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Nontypeable Haemophilus influenzae and Streptococcus pneumoniae bind respiratory syncytial virus glycoprotein

21 January 2018

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Human rhinovirus infection induces airway epithelial cell production of human beta-defensin 2 both in vitro and in vivo

21 January 2018

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A member of the cathelicidin family of antimicrobial peptides is produced in the upper airway of the chinchilla and its mRNA expression is altered by common viral and bacterial co-pathogens of otitis media

21 January 2018

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Insights into the interaction between influenza virus and pneumococcus

21 January 2018

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Developing a nontypeable Haemophilus influenzae (NTHi) vaccine

21 January 2018

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Nontypeable Haemophilus influenzae: challenges in developing a vaccine

21 January 2018

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Passive transfer of antiserum specific for immunogens derived from a nontypeable Haemophilus influenzae adhesin and lipoprotein D prevents otitis media after heterologous challenge

21 January 2018

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Co-infection of the cotton rat (Sigmodon hispidus) with Staphylococcus aureus and influenza A virus results in synergistic disease.

21 January 2018

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Anatomy of the nasal cavity in the chinchilla

21 January 2018

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Mouse models for the study of mucosal vaccination against otitis media

21 January 2018

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Contribution of Moraxella catarrhalis type IV pili to nasopharyngeal colonization and biofilm formation

21 January 2018

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Differential uptake and processing of a Haemophilus influenzae P5-derived immunogen by chinchilla dendritic cells

21 January 2018

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Role of complement in defense of the middle ear revealed by restoring the virulence of nontypeable Haemophilus influenzae siaB mutants

21 January 2018

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A carcinoembryonic antigen-related cell adhesion molecule 1 homologue plays a pivotal role in nontypeable Haemophilus influenzae colonization of the chinchilla nasopharynx via the outer membrane protein P5-homologous adhesin

21 January 2018

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Identification and characterization of a mucosal antimicrobial peptide expressed by the chinchilla (Chinchilla lanigera) airway.

21 January 2018

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Mucin gene cDNA sequence characterization in chinchilla middle ear epithelium.

21 January 2018

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Developing animal models for polymicrobial diseases

21 January 2018

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Genomic Sequence of an Otitis Media Isolate of Nontypeable Haemophilus influenzae: Comparative Study with H. influenzae Serotype d, Strain KW20

21 January 2018

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Protein D of Haemophilus influenzae: a protective nontypeable H. influenzae antigen and a carrier for pneumococcal conjugate vaccines

21 January 2018

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Impact of different case definitions for acute otitis media on the efficacy estimates of a pneumococcal conjugate vaccine

21 January 2018

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Pneumococcal Haemophilus influenzae protein D conjugate vaccine induces antibodies that inhibit glycerophosphodiester phosphodiesterase activity of protein D.

21 January 2018

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Moraxella (Branhamella) Catarrhalis-induced Experimental Otitis Media in the Chinchilla

21 January 2018

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Early Acute Otitis Media: Determined by Exposure to Respiratory Pathogens

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERV.09.63

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21 August 2017

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PubMed ID

19627188