Three decades of the class A beta-lactamase acyl-enzyme. (Q37524130)

PubMed publication ID

20 August 2017

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title

Three decades of the class A beta-lactamase acyl-enzyme (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6902449&resulttype=core&format=json

13 May 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6902449&resulttype=core&format=json

13 May 2020

2

Shahriar Mobashery

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6902449&resulttype=core&format=json

13 May 2020

publication date

1 October 2009

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PubMed publication ID

19538154

Current Protein and Peptide Science

20 August 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6902449&resulttype=core&format=json

13 May 2020

volume

10

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6902449&resulttype=core&format=json

13 May 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6902449&resulttype=core&format=json

13 May 2020

page(s)

401-407

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6902449&resulttype=core&format=json

Beta-lactamases as fully efficient enzymes. Determination of all the rate constants in the acyl-enzyme mechanism

13 May 2020

cites work

1 reference

12 December 2020

Cryoenzymology of beta-lactamases

1 reference

12 December 2020

Investigation of the mechanism of the cell wall DD-carboxypeptidase reaction of penicillin-binding protein 5 of Escherichia coli by quantum mechanics/molecular mechanics calculations.

1 reference

12 December 2020

Isolation of a covalent intermediate in beta -lactamase I catalysis

1 reference

12 December 2020

The importance of a critical protonation state and the fate of the catalytic steps in class A beta-lactamases and penicillin-binding proteins

1 reference

12 December 2020

A point mutation leads to altered product specificity in beta-lactamase catalysis

1 reference

12 December 2020

Site-directed mutagenesis of .beta.-lactamase leading to accumulation of a catalytic intermediate

1 reference

12 December 2020

Kinship and diversification of bacterial penicillin-binding proteins and beta-lactamases

1 reference

12 December 2020

Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.

1 reference

12 December 2020

beta-Lactamase proceeds via an acyl-enzyme intermediate. Interaction of the Escherichia coli RTEM enzyme with cefoxitin

1 reference

12 December 2020

Partial amino acid sequence of penicillinase coded by Escherichia coli plasmid R6K

1 reference

12 December 2020

The discovery of cell wall active antibacterial antibiotics

1 reference

12 December 2020

A catalytically-impaired class A beta-lactamase: 2 A crystal structure and kinetics of the Bacillus licheniformis E166A mutant

1 reference

12 December 2020

Inactivation of the RTEM beta-lactamase from Escherichia coli. Interaction of penam sulfones with enzyme

1 reference

12 December 2020

A dynamic structure for the acyl-enzyme species of the antibiotic aztreonam with the Citrobacter freundii beta-lactamase revealed by infrared spectroscopy and molecular dynamics simulations

1 reference

12 December 2020

The deacylation mechanism of AmpC beta-lactamase at ultrahigh resolution

1 reference

12 December 2020

The Acylation Mechanism of CTX-M β-Lactamase at 0.88 Å Resolution

1 reference

12 December 2020

The role of lysine-234 in beta-lactamase catalysis probed by site-directed mutagenesis

1 reference

12 December 2020

Conformation of penicillin as a transition-state analog of the substrate of peptidoglycan transpeptidase.

1 reference

12 December 2020

Cefoxitin, a Semisynthetic Cephamycin Antibiotic: Resistance to Beta-Lactamase Inactivation

1 reference

12 December 2020

6-β-Bromo- and 6-β-iodo penicillanic acid, two novel β-lactamase inhibitors

1 reference

12 December 2020

Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322

1 reference

12 December 2020

Structure, function, and inhibition along the reaction coordinate of CTX-M beta-lactamases

1 reference

12 December 2020

Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution

1 reference

12 December 2020

Certain monocyclic beta-lactams are beta-lactamase substrates: nocardicin A and desthiobenzylpenicillin

1 reference

12 December 2020

Enzyme-induced strain/distortion in the ground-state ES complex in beta-lactamase catalysis revealed by FTIR.

1 reference

12 December 2020

Side-chain mobility of the beta-lactamase A state probed by electron spin resonance spectroscopy

1 reference

12 December 2020

Evidence for an oxyanion hole in serine beta-lactamases and DD-peptidases

1 reference

12 December 2020

Bacterial resistance to beta-lactam antibiotics: crystal structure of beta-lactamase from Staphylococcus aureus PC1 at 2.5 A resolution.

1 reference

12 December 2020

Cutting and stitching: the cross-linking of peptidoglycan in the assembly of the bacterial cell wall

1 reference

12 December 2020

A new TEM beta-lactamase double mutant with broadened specificity reveals substrate-dependent functional interactions.

1 reference

12 December 2020

Structural and mechanistic aspects of evolution of beta-lactamases and penicillin-binding proteins

1 reference

12 December 2020

Mechanism of penicillin action: penicillin and substrate bind covalently to the same active site serine in two bacterial D-alanine carboxypeptidases

1 reference

12 December 2020

Substrate specificity of bacterial DD-peptidases (penicillin-binding proteins).

1 reference

12 December 2020

Effects of site-specific mutagenesis of tyrosine 105 in a class A beta-lactamase

1 reference

12 December 2020

Sequence of active site peptides from the penicillin-sensitive D-alanine carboxypeptidase of Bacillus subtilis. Mechanism of penicillin action and sequence homology to beta-lactamases

1 reference

12 December 2020

Naturally-occurring beta-lactamase inhibitors with antibacterial activity

1 reference

12 December 2020

Trapping the acyl-enzyme intermediate in beta-lactamase I catalysis

1 reference

12 December 2020

Clavulanate inactivation of Staphylococcus aureus beta-lactamase

1 reference

12 December 2020

6-(hydroxyalkyl)penicillanates as probes for mechanisms of beta-lactamases

1 reference

12 December 2020

On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target

1 reference

12 December 2020

Chemical studies on the inactivation of Escherichia coli RTEM β-lactamase by clavulanic acid

1 reference

12 December 2020

Site-directed mutagenesis of glutamate-166 in beta-lactamase leads to a branched path mechanism

1 reference

12 December 2020

CP-45,899, a Beta-Lactamase Inhibitor That Extends the Antibacterial Spectrum of Beta-Lactams: Initial Bacteriological Characterization

1 reference

12 December 2020

Cephamycins, a New Family of β-Lactam Antibiotics I. Production by Actinomycetes, Including Streptomyces lactamdurans sp. n

1 reference

12 December 2020

Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity

1 reference

12 December 2020

Molecular evolution of bacterial beta-lactam resistance

1 reference

12 December 2020

Cryoenzymology of staphylococcal beta-lactamase: trapping a serine-70-linked acyl-enzyme

1 reference

12 December 2020

Substitution of Asp for Asn at position 132 in the active site of TEM beta-lactamase. Activity toward different substrates and effects of neighboring residues

1 reference

12 December 2020

Identification of the site of covalent attachment of nafcillin, a reversible suicide inhibitor of β-lactamase

1 reference

12 December 2020

6-beta-bromopenicillanic acid, a potent beta-lactamase inhibitor

1 reference

12 December 2020

Lysine-73 is involved in the acylation and deacylation of beta-lactamase

1 reference

12 December 2020

6 beta-Iodopenicillanic acid (UI-38,006), a beta-lactamase inhibitor that extends the antibacterial spectrum of beta-lactam compounds: initial bacteriological characterization

1 reference

12 December 2020

Kinetic studies on the inactivation of Escherichia coli RTEM β-lactamase by clavulanic acid

1 reference

12 December 2020

A semi-synthetic penicillinase inactivator

1 reference

12 December 2020

Selective reminiscences of beta-lactam antibiotics: early research on penicillin and cephalosporins

1 reference

12 December 2020

6 β-Bromopenicillanic acid inactivates β-lactamase I

1 reference

12 December 2020

Penicillin target enzyme and the antibiotic binding site

1 reference

12 December 2020

Multiple conformations of the acylenzyme formed in the hydrolysis of methicillin by Citrobacter freundii beta-lactamase: a time-resolved FTIR spectroscopic study

1 reference

12 December 2020

13 Cryoenzymology: The study of enzyme catalysis at subzero temperatures

1 reference

12 December 2020

Insights into class D beta-lactamases are revealed by the crystal structure of the OXA10 enzyme from Pseudomonas aeruginosa

1 reference

12 December 2020

10.2174/138920309789351967

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6902449&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6902449&resulttype=core&format=json

13 May 2020

PubMed publication ID

19538154

1 reference