Advanced glycation end products (AGE) and diabetes: cause, effect, or both? (Q37520014)

20 August 2017

Advanced glycation end products (AGE) and diabetes: cause, effect, or both? (English)

1 reference

20 August 2017

Helen Vlassara

1

1 reference

PMCID

3903318

20 August 2017

Jaime Uribarri

series ordinal

2

1 reference

20 August 2017

1 January 2014

1 reference

20 August 2017

Current diabetes report

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20 August 2017

14

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20 August 2017

453

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20 August 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1007/s11892-013-0453-1

20 August 2017

0 references

cites work

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23 August 2017

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Advanced glycation end product receptor-1 transgenic mice are resistant to inflammation, oxidative stress, and post-injury intimal hyperplasia

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Increased levels of advanced glycation endproducts in the lenses and blood vessels of cigarette smokers.

23 August 2017

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23 August 2017

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Tobacco smoke is a source of toxic reactive glycation products

23 August 2017

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Elevated AGE-modified ApoB in sera of euglycemic, normolipidemic patients with atherosclerosis: relationship to tissue AGEs

23 August 2017

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Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy

23 August 2017

1 reference

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Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.

23 August 2017

1 reference

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Role of the Maillard reaction in diabetes mellitus and diseases of aging

23 August 2017

1 reference

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23 August 2017

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Nutritional and toxicological aspects of the Maillard browning reaction in foods

23 August 2017

1 reference

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Increasing prevalence of the metabolic syndrome among u.s. Adults.

6 September 2017

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Role of megalin in endocytosis of advanced glycation end products: implications for a novel protein binding to both megalin and advanced glycation end products.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Aminoguanidine exerts a beta-cell function-preserving effect in high glucose-cultured beta-cells (INS-1).

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Effects of OPB-9195, anti-glycation agent, on experimental diabetic neuropathy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

The rising global burden of diabetes and its complications: estimates and projections to the year 2010.

28 September 2017

1 reference

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Long-term effects of aminoguanidine on insulin release and biosynthesis: evidence that the formation of advanced glycosylation end products inhibits B cell function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Advanced glycosylation end products in patients with diabetic nephropathy

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Increased serum levels of advanced glycation endproducts predict total, cardiovascular and coronary mortality in women with type 2 diabetes: a population-based 18 year follow-up study

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Insulin resistance and type 2 diabetes in high-fat-fed mice are linked to high glycotoxin intake

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

High serum pentosidine concentrations are associated with increased arterial stiffness and thickness in patients with type 2 diabetes

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Restriction of dietary glycotoxins reduces excessive advanced glycation end products in renal failure patients

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Improved insulin sensitivity is associated with restricted intake of dietary glycoxidation products in the db/db mouse.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Aminoguanidine ameliorates overexpression of prosclerotic growth factors and collagen deposition in experimental diabetic nephropathy

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Immunohistochemical study of human advanced glycation end-products (AGE) and growth factors in cardiac tissues of patients on maintenance dialysis and with kidney transplantation.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Aminoguanidine has an anti-atherogenic effect in the cholesterol-fed rabbit.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

Identification of the major site of apolipoprotein B modification by advanced glycosylation end products blocking uptake by the low density lipoprotein receptor.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903318

ADME evaluation in drug discovery. 1. Applications of genetic algorithms to the prediction of blood-brain partitioning of a large set of drugs.

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11892-013-0453-1

Effect of a new vitamin E-coated membrane on glycoxidation during hemodialysis

21 January 2018

1 reference

12 December 2020

Nonenzymatic glycation of bovine serum albumin by fructose (fructation). Comparison with the Maillard reaction initiated by glucose

1 reference

12 December 2020

Antioxidants reverse the antiproliferative effect of high glucose and advanced glycosylation end products in cultured rat mesangial cells

1 reference

12 December 2020

Effects of aminoguanidine in preventing experimental diabetic nephropathy are related to the duration of treatment

1 reference

12 December 2020

Good glycaemic control reduces oxidation and glycation end-products in collagen of diabetic rats

1 reference

12 December 2020

Progression of nephropathy in spontaneous diabetic rats is prevented by OPB-9195, a novel inhibitor of advanced glycation

1 reference

12 December 2020

Antioxidant treatment of experimental diabetic retinopathy in rats with nicanartine

1 reference

12 December 2020

Alpha-lipoic acid reduces expression of vascular cell adhesion molecule-1 and endothelial adhesion of human monocytes after stimulation with advanced glycation end products

1 reference

12 December 2020

Increased advanced glycation end products in atherosclerotic lesions of patients with end-stage renal disease

1 reference

12 December 2020

Dietary glycotoxins: inhibition of reactive products by aminoguanidine facilitates renal clearance and reduces tissue sequestration

1 reference

12 December 2020

Suppression of N(epsilon)-(carboxymethyl)lysine generation by the antioxidant N-acetylcysteine

1 reference

12 December 2020

Single oral challenge by advanced glycation end products acutely impairs endothelial function in diabetic and nondiabetic subjects

1 reference

12 December 2020

The RAGE pathway: activation and perpetuation in the pathogenesis of diabetic neuropathy

1 reference

12 December 2020

10.1007/S11892-013-0453-1

Identifiers

DOI

1 reference

20 August 2017

1 reference

20 August 2017

1 reference

PMCID

3903318