A phase II study of cixutumumab (IMC-A12, NSC742460) in advanced hepatocellular carcinoma. (Q37515263)

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22 February 2020

title

A phase II study of cixutumumab (IMC-A12, NSC742460) in advanced hepatocellular carcinoma (English)

1 reference

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22 February 2020

3

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Jinru Shia

7

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Seth Katz

9

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Leonard B. Saltz

14

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author name string

Ghassan K Abou-Alfa

1

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Marinela Capanu

2

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Jennifer Ma

4

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22 February 2020

Joanne F Chou

5

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Bolorsukh Gansukh

6

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Marcia Kalin

8

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Leslie Abad

10

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Diane L Reidy-Lagunes

11

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David P Kelsen

12

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Helen X Chen

13

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publication date

14 September 2013

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22 February 2020

published in

Journal of Hepatology

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volume

60

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issue

2

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22 February 2020

page(s)

319-324

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Case series of dermatologic events associated with the insulin-like growth factor receptor 1 inhibitor cixutumumab

22 February 2020

cites work

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Effect of blocking IGF-I receptor on growth of human hepatocellular carcinoma cells

23 August 2017

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Blockade of IGF-1 receptor tyrosine kinase has antineoplastic effects in hepatocellular carcinoma cells

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A possible role for insulin-like growth factor-binding protein-3 autocrine/paracrine loops in controlling hepatocellular carcinoma cell proliferation.

23 August 2017

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Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors

23 August 2017

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Activation of insulin-like growth factor II signaling by mutant type p53: physiological implications for potentiation of IGF-II signaling by p53 mutant 249.

23 August 2017

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Focal overexpression of insulin-like growth factor 2 by hepatocytes and cholangiocytes in viral liver cirrhosis

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SEARCH: a phase III, randomized, double-blind, placebo-controlled trial of sorafenib plus erlotinib in patients with advanced hepatocellular carcinoma.

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Inhibition of hepatocellular carcinoma growth by antisense oligonucleotides to type I insulin-like growth factor receptor in vitro and in an orthotopic model

2 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24045151

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12 December 2020

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Insulin-like growth factor I (IGF-I) replacement therapy increases albumin concentration in liver cirrhosis: results of a pilot randomized controlled clinical trial

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24045151

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12 December 2020

based on heuristic

Disturbed synthesis of insulinlike growth factor I and its binding proteins may influence renal function changes in liver cirrhosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24045151

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12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JHEP.2013.09.008

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22 February 2020

1 reference

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22 February 2020

1 reference