Biomarkers of AAA progression. Part 1: extracellular matrix degeneration (Q37495418)

20 August 2017

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title

Biomarkers of AAA progression. Part 1: extracellular matrix degeneration (English)

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20 August 2017

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Femke A M V I Hellenthal

1

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20 August 2017

Willem A Buurman

2

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20 August 2017

Will K W H Wodzig

3

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20 August 2017

Geert Willem H Schurink

4

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20 August 2017

language of work or name

English

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publication date

26 May 2009

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Nature Reviews Cardiology

20 August 2017

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20 August 2017

6

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20 August 2017

7

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20 August 2017

464-474

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Surrogate end points in clinical trials: are we being misled?

20 August 2017

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Elevated circulating levels of inflammatory cytokines in patients with abdominal aortic aneurysm.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Identification of matrix metalloproteinases 3 (stromelysin-1) and 9 (gelatinase B) in abdominal aortic aneurysm

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Production of MMPs in human cerebral endothelial cells and their role in shedding adhesion molecules

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Ubiquitous Elevation of Matrix Metalloproteinase-2 Expression in the Vasculature of Patients With Abdominal Aneurysms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Abdominal aortic aneurysm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Abdominal aortic aneurysm

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Two decades of abdominal aortic aneurysm repair: have we made any progress?

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Two-year outcomes after conventional or endovascular repair of abdominal aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Mortality results for randomised controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Natural history of patients with abdominal aortic aneurysm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Discontinuous, staccato growth of abdominal aortic aneurysms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Anatomic characteristics of ruptured abdominal aortic aneurysm on conventional CT scans: Implications for rupture risk.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Prediction of rupture risk in abdominal aortic aneurysm during observation: wall stress versus diameter

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Circulating markers of abdominal aortic aneurysm presence and progression

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Vascular biomarkers and surrogates in cardiovascular disease.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Elastin degradation in abdominal aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Aortic aneurysm formation: lessons from human studies and experimental models

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Elastase-induced experimental aneurysms in rats

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Mouse models of abdominal aortic aneurysms

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Changing concepts of atherogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Medial neovascularization in abdominal aortic aneurysms: a histopathologic marker of aneurysmal degeneration with pathophysiologic implications.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Collagen degradation in the abdominal aneurysm: a conspiracy of matrix metalloproteinase and cysteine collagenases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Structure of large arteries: orientation of elastin in rabbit aortic internal elastic lamina and in the elastic lamellae of aortic media

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Abdominal aortic aneurysms are associated with altered matrix proteins of the nonaneurysmal aortic segments

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

The role of inflammation in nonspecific abdominal aortic aneurysm disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Serum elastin peptides in the preoperative evaluation of abdominal aortic aneurysms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

The relationship between abdominal aortic aneurysm distensibility and serum markers of elastin and collagen metabolism.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

The plasma level of matrix metalloproteinase 9 may predict the natural history of small abdominal aortic aneurysms. A preliminary study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Serum-elastin-peptides as a predictor of expansion of small abdominal aortic aneurysms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Five-year results of elastin and collagen markers as predictive tools in the management of small abdominal aortic aneurysms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Plasma levels of plasmin-antiplasmin-complexes are predictive for small abdominal aortic aneurysms expanding to operation-recommendable sizes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

The composition and mechanical properties of abdominal aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Elastolytic and collagenolytic studies of arteries. Implications for the mechanical properties of aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Collagen types in various layers of the human aorta and their changes with the atherosclerotic process

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Abdominal aortic aneurysms: basic mechanisms and clinical implications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Aminoterminal propeptide of type III procollagen in the follow-up of patients with abdominal aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Increased turnover of collagen in abdominal aortic aneurysms, demonstrated by measuring the concentration of the aminoterminal propeptide of type III procollagen in peripheral and aortal blood samples

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

An ELISA for elastase alpha 1-protease inhibitor complexes in human plasma and serum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Transient exposure to elastase induces mouse aortic wall smooth muscle cell production of MCP-1 and RANTES during development of experimental aortic aneurysm.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Elastase promotes aortic dilation by inhibiting Ca2+ influx into vascular smooth muscle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Search for serum biomarkers associated with abdominal aortic aneurysm growth--a pilot study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Systemic levels of cotinine and elastase, but not pulmonary function, are associated with the progression of small abdominal aortic aneurysms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Aortic aneurysms: It's all about the stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Differential regulation of protease activated receptor-1 and tissue plasminogen activator expression by shear stress in vascular smooth muscle cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Mitochondrial redox control of matrix metalloproteinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Collagenase activity of the human aorta. A comparison of patients with and without abdominal aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Demonstration of interstitial collagenase in abdominal aortic aneurysm disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Expression of collagenase-3 (MMP-13) in human abdominal aortic aneurysms and vascular smooth muscle cells in culture

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Matrix metalloproteinase 8 (neutrophil collagenase) in the pathogenesis of abdominal aortic aneurysm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Matrix metalloproteinase-8 and -9 are increased at the site of abdominal aortic aneurysm rupture

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Evidence for altered balance between matrix metalloproteinases and their inhibitors in human aortic diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Activated forms of MMP2 and MMP9 in abdominal aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Elevated plasma levels of matrix metalloproteinase-9 in patients with abdominal aortic aneurysms: a circulating marker of degenerative aneurysm disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Aminoterminal propeptide of type III procollagen and matrix metalloproteinases-2 and -9 failed to serve as serum markers for abdominal aortic aneurysm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Systemic dilation diathesis in patients with abdominal aortic aneurysms: a role for matrix metalloproteinase-9?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Expansion of small-diameter abdominal aortic aneurysms is not reflected by the release of inflammatory mediators IL-6, MMP-9 and CRP in plasma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Lysosomal cysteine proteases in atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Regulation of elastinolytic cysteine proteinase activity in normal and cathepsin K-deficient human macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Cystatin C deficiency increases elastic lamina degradation and aortic dilatation in apolipoprotein E-null mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Cystatin C deficiency in human atherosclerosis and aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Cystatin C deficiency is associated with the progression of small abdominal aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Genetic approach to the role of cysteine proteases in the expansion of abdominal aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

The role of plasminogen activators in the regulation of connective tissue metalloproteinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Degradation of connective tissue matrices by macrophages. I. Proteolysis of elastin, glycoproteins, and collagen by proteinases isolated from macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Relationships between activators and inhibitors of plasminogen, and the progression of small abdominal aortic aneurysms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

High levels of homocysteine, lipoprotein (a) and plasminogen activator inhibitor-1 are present in patients with abdominal aortic aneurysm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Coagulation and fibrinolysis in patients undergoing operation for ruptured and nonruptured infrarenal abdominal aortic aneurysms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Activated protein C-protein C inhibitor complex: a new biological marker for aortic aneurysms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Activated protein C-protein C inhibitor complex in patients with abdominal aortic aneurysms: is it associated with diameter and growth rate?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.80

Mortality results for randomised controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms. The UK Small Aneurysm Trial Participants

31 March 2020

1 reference

12 December 2020

Elastin metabolism of the infrarenal aorta

1 reference

12 December 2020

Radioimmunoassay of the carboxyterminal propeptide of human type I procollagen

1 reference

12 December 2020

Histological features of human abdominal aortic aneurysm are not related to clinical characteristics

1 reference

12 December 2020

Failure of elastin or collagen as possible critical connective tissue alterations underlying aneurysmal dilatation

1 reference

12 December 2020

High levels of homocysteine, lipoprotein (a) and plasminogen activator inhibitor-1 are present in patients with abdominal aortic aneurysm

1 reference

12 December 2020

Altered aortic protease and antiprotease activity in patients with ruptured abdominal aortic aneurysms

1 reference

12 December 2020

Elastin in blood vessels.

1 reference

12 December 2020

Th2-predominant inflammation and blockade of IFN-gamma signaling induce aneurysms in allografted aortas

1 reference

12 December 2020

Diagnostic applications of cystatin C.

1 reference

12 December 2020

Possible key role for plasmin in the pathogenesis of abdominal aortic aneurysms

1 reference

12 December 2020

Mathematical morphologic analysis of the aortic medial structure. Biomechanical implications.

1 reference

12 December 2020

On the mechanism of the reaction between human alpha 2-antiplasmin and plasmin

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRCARDIO.2009.80

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20 August 2017

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