Targeted SERCA2a gene expression identifies molecular mechanism and therapeutic target for arrhythmogenic cardiac alternans (Q37480953)

20 August 2017

Targeted SERCA2a gene expression identifies molecular mechanism and therapeutic target for arrhythmogenic cardiac alternans (English)

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20 August 2017

Michael J Cutler

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20 August 2017

Xiaoping Wan

2

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20 August 2017

Kenneth R Laurita

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20 August 2017

Roger J Hajjar

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20 August 2017

David S Rosenbaum

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20 August 2017

1 December 2009

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Circulation: Arrhythmia and Electrophysiology

20 August 2017

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20 August 2017

2

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20 August 2017

6

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20 August 2017

686-694

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describes a project that uses

20 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2795134/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Intracellular Ca alternans: coordinated regulation by sarcoplasmic reticulum release, uptake, and leak

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Altered cardiac myocyte Ca regulation in heart failure.

23 August 2017

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From pulsus to pulseless: the saga of cardiac alternans

23 August 2017

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Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias

23 August 2017

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Microvolt T-Wave Alternans Distinguishes Between Patients Likely and Patients Not Likely to Benefit From Implanted Cardiac Defibrillator Therapy: A Solution to the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II Conundrum

23 August 2017

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Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling

23 August 2017

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Targeting calcium cycling proteins in heart failure through gene transfer

23 August 2017

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Role of structural barriers in the mechanism of alternans-induced reentry

23 August 2017

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Functional coupling between glycolysis and excitation-contraction coupling underlies alternans in cat heart cells

23 August 2017

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Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a

23 August 2017

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Intracellular Ca(2+) dynamics and the stability of ventricular tachycardia.

23 August 2017

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A new generation of Ca2+ indicators with greatly improved fluorescence properties

23 August 2017

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Cardiac alternans: diverse mechanisms and clinical manifestations

23 August 2017

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Role of calcium cycling versus restitution in the mechanism of repolarization alternans

23 August 2017

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Alternans of action potential duration after abrupt shortening of cycle length: differences between dog Purkinje and ventricular muscle fibers

14 September 2017

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Action potential duration alternans in dog Purkinje and ventricular muscle fibers. Further evidence in support of two different mechanisms

28 September 2017

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Focal modification of electrical conduction in the heart by viral gene transfer

28 September 2017

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Regional electromechanical alternans in anesthetized pig hearts: modulation by mechanoelectric feedback.

26 June 2018

1 reference

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A model of the ventricular cardiac action potential. Depolarization, repolarization, and their interaction

26 June 2018

1 reference

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Insulin Resistance and Abnormal Electrocardiograms in Patients With High Blood Pressure

26 June 2018

1 reference

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Effects of verapamil on canine Purkinje fibres and ventricular muscle fibres with particular reference to the alternation of action potential duration after a sudden increase in driving rate

26 June 2018

1 reference

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Molecular correlates of repolarization alternans in cardiac myocytes

26 June 2018

1 reference

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Coupled dynamics of voltage and calcium in paced cardiac cells

2 September 2018

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Action potential duration restitution and alternans in rabbit ventricular myocytes: the key role of intracellular calcium cycling.

2 September 2018

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Sarcoplasmic reticulum calcium content fluctuation is the key to cardiac alternans

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795134

Hysteresis effect implicates calcium cycling as a mechanism of repolarization alternans

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795134

Intracellular calcium handling heterogeneities in intact guinea pig hearts

2 September 2018

1 reference

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Possible contribution of the sarcoplasmic reticulum Ca(2+) pump function to electrical and mechanical alternans

2 September 2018

1 reference

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Mechanisms of discordant alternans and induction of reentry in simulated cardiac tissue

2 September 2018

1 reference

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Prevention of ventricular arrhythmias with sarcoplasmic reticulum Ca2+ ATPase pump overexpression in a porcine model of ischemia reperfusion

2 September 2018

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12 December 2020

Sarcoplasmic Reticulum Ca2+ Release Causes Myocyte Depolarization : Underlying Mechanism and Threshold for Triggered Action Potentials

1 reference

12 December 2020

Transmural heterogeneity of calcium handling in canine

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12 December 2020

Significance of discordant ST alternans in ventricular fibrillation

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12 December 2020

Ventricular tachycardia after infarction: Sources of coronary blood flow to the infarct zone

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12 December 2020

Ca2+ and Mg-ATP activated potassium channels from rat pulmonary artery

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12 December 2020

Differences in the electrophysiological response of canine ventricular epicardium and endocardium to ischemia. Role of the transient outward current

1 reference

12 December 2020

Electrical alternans and vulnerability to ventricular arrhythmias

1 reference

12 December 2020

Dexmedetomidine produces similar alterations in the determinants of left ventricular afterload in conscious dogs before and after the development of pacing-induced cardiomyopathy

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12 December 2020

Mechanism linking T-wave alternans to the genesis of cardiac fibrillation

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12 December 2020

Effect of heart rate on cardiac membrane potentials and the unipolar electrogram

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12 December 2020

Electrical alternans with emphasis on recent observations made by means of single-cell electrical recording

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12 December 2020

Cardiac alternans do not rely on diastolic sarcoplasmic reticulum calcium content fluctuations

1 reference

12 December 2020

10.1161/CIRCEP.109.863118

Identifiers

DOI

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20 August 2017

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20 August 2017

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