N-terminal domains elicit formation of functional Pmel17 amyloid fibrils (Q37467613)

20 August 2017

N-terminal domains elicit formation of functional Pmel17 amyloid fibrils (English)

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20 August 2017

7

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20 August 2017

2

Guillaume van Niel

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Graça Raposo

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object named as

Graça Raposo

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20 August 2017

James Shorter

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Michael S. Marks

object named as

Michael S Marks

11

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Jeffery W. Kelly

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object named as

Jeffery W Kelly

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20 August 2017

1

Brenda Watt

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20 August 2017

Kelvin C Luk

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author name string

Douglas M Fowler

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20 August 2017

Ilse Hurbain

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20 August 2017

Steven E Stayrook

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20 August 2017

language of work or name

English

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publication date

1 December 2009

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Journal of Biological Chemistry

20 August 2017

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20 August 2017

284

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51

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20 August 2017

35543-35555

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describes a project that uses

20 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2790984/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The repeat domain of the melanosome fibril protein Pmel17 forms the amyloid core promoting melanin synthesis

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Formation of Pmel17 amyloid is regulated by juxtamembrane metalloproteinase cleavage, and the resulting C-terminal fragment is a substrate for gamma-secretase

23 August 2017

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23 August 2017

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MHC class II presentation of gp100 epitopes in melanoma cells requires the function of conventional endosomes and is influenced by melanosomes.

23 August 2017

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Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival

23 August 2017

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Premelanosome amyloid-like fibrils are composed of only golgi-processed forms of Pmel17 that have been proteolytically processed in endosomes

23 August 2017

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23 August 2017

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A missense mutation in PMEL17 is associated with the Silver coat color in the horse

23 August 2017

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23 August 2017

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Dual loss of ER export and endocytic signals with altered melanosome morphology in the silver mutation of Pmel17

23 August 2017

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23 August 2017

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Retrotransposon insertion in SILV is responsible for merle patterning of the domestic dog.

23 August 2017

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Functional amyloid formation within mammalian tissue

23 August 2017

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The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function

23 August 2017

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Structural insights into a yeast prion illuminate nucleation and strain diversity

23 August 2017

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The Dominant white, Dun and Smoky color variants in chicken are associated with insertion/deletion polymorphisms in the PMEL17 gene

23 August 2017

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A novel splice variant of Pmel17 expressed by human melanocytes and melanoma cells lacking some of the internal repeats.

23 August 2017

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Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis

23 August 2017

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Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

23 August 2017

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Pallidin is a component of a multi-protein complex involved in the biogenesis of lysosome-related organelles

23 August 2017

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23 August 2017

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Analysis of prion factors in yeast

23 August 2017

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BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules

23 August 2017

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Pmel17 initiates premelanosome morphogenesis within multivesicular bodies

23 August 2017

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A model for melanosome biogenesis based on the purification and analysis of early melanosomes

23 August 2017

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Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells

23 August 2017

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The structure of a PKD domain from polycystin-1: implications for polycystic kidney disease

23 August 2017

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Polymerization of 5,6-dihydroxyindole-2-carboxylic acid to melanin by the pmel 17/silver locus protein

23 August 2017

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nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts

23 August 2017

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The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

23 August 2017

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A melanocyte-specific gene, Pmel 17, maps near the silver coat color locus on mouse chromosome 10 and is in a syntenic region on human chromosome 12

23 August 2017

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Effects of ph and type of sugar in the medium on tyrosinase activity in cultured melanoma cells

23 August 2017

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Oligopeptide repeats in the yeast protein Sup35p stabilize intermolecular prion interactions

6 September 2017

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Sialylated core 1 O-glycans influence the sorting of Pmel17/gp100 and determine its capacity to form fibrils

14 September 2017

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The repeat domain of the melanosomal matrix protein PMEL17/GP100 is required for the formation of organellar fibers

14 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Recycling Compartments and the Internal Vesicles of Multivesicular Bodies Harbor Most of the Cholesterol Found in the Endocytic Pathway

14 September 2017

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Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O.

14 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Anti-melanoma monoclonal antibody HMB-45 on enhanced chemiluminescence-western blotting recognizes a 30-35 kDa melanosome-associated sialated glycoprotein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Quantitative evaluation of congo red binding to amyloid-like proteins with a beta-pleated sheet conformation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Role of different regions of alpha-synuclein in the assembly of fibrils.

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

The structural basis of yeast prion strain variants

26 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Architecture of Ure2p prion filaments: the N-terminal domains form a central core fiber

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Molecular basis of a yeast prion species barrier

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Mechanism of inhibition of Psi+ prion determinant propagation by a mutation of the N-terminus of the yeast Sup35 protein

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Effects of the developmental colour mutations silver and recessive spotting on proliferation of diploid and immortal mouse melanocytes in culture

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Sequence determinants regulating fibrillation of human alpha-synuclein

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Receptor tyrosine kinases positively regulate BACE activity and Amyloid-beta production through enhancing BACE internalization.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Lipid raft-associated protein sorting in exosomes.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2790984

Oligopeptide-repeat expansions modulate ‘protein-only’ inheritance in yeast

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M109.047449

Structural features of the Abeta amyloid fibril elucidated by limited proteolysis

21 January 2018

1 reference

12 December 2020

Genetic variations in the fine structure and ontogeny of mouse melanin granules

1 reference

12 December 2020

Golgi-melanosome relationship in human melanoma in vitro

1 reference

12 December 2020

Lysosomal hydrolases are present in melanosomes and are elevated in melanizing cells

1 reference

12 December 2020

Electron microscopy of melanocytes: The fine structure of hair-bulb premelanosomes

1 reference

12 December 2020

Visualization of aggregation of the Rnq1 prion domain and cross-seeding interactions with Sup35NM

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12 December 2020

Identifiers

DOI

10.1074/JBC.M109.047449

1 reference

20 August 2017

1 reference

20 August 2017

1 reference