The E163K DJ-1 mutant shows specific antioxidant deficiency (Q37440893)

20 August 2017

The E163K DJ-1 mutant shows specific antioxidant deficiency (English)

1 reference

20 August 2017

Chenere P Ramsey

1

1 reference

20 August 2017

Benoit I Giasson

series ordinal

2

1 reference

20 August 2017

language of work or name

English

0 references

publication date

16 September 2008

1 reference

20 August 2017

1 reference

20 August 2017

1239

1 reference

20 August 2017

1-11

1 reference

describes a project that uses

20 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2783860/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1 † , ‡

23 August 2017

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Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6

23 August 2017

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Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging

23 August 2017

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Implications of genetics on the diagnosis and care of patients with Parkinson disease

23 August 2017

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The ubiquitin-proteasome system and neurodegenerative disorders

23 August 2017

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23 August 2017

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DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity

23 August 2017

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Nosology of Parkinson's disease: looking for the way out of a quagmire

23 August 2017

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Molecular pathophysiology of Parkinson's disease

23 August 2017

1 reference

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Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death

23 August 2017

1 reference

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The biochemistry of Parkinson's disease

23 August 2017

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Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

23 August 2017

1 reference

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The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation

23 August 2017

1 reference

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Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

23 August 2017

1 reference

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The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

DJ-1 has a role in antioxidative stress to prevent cell death

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease

23 August 2017

1 reference

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Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition

23 August 2017

1 reference

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Crystal structures of human DJ-1 and Escherichia coli Hsp31, which share an evolutionarily conserved domain

23 August 2017

1 reference

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Crystal structure of DJ-1/RS and implication on familial Parkinson's disease

23 August 2017

1 reference

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Crystallization and preliminary crystallographic analysis of DJ-1, a protein associated with male fertility and parkinsonism

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

On the oligomeric state of DJ-1 protein and its mutants associated with Parkinson Disease. A combined computational and in vitro study.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Differential Effects of Parkinson's Disease-associated Mutations on Stability and Folding of DJ-1

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

DJ-1 and UCH-L1 gene activity patterns in the brains of controls, Parkinson and schizophrenia patients and in rodents.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

DJ-1 mutations and parkinsonism-dementia-amyotrophic lateral sclerosis complex.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

DJ-1 is present in a large molecular complex in human brain tissue and interacts with alpha-synuclein.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Expression of DJ-1 in the adult mouse CNS.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Dimerization of Parkinson's disease-causing DJ-1 and formation of high molecular weight complexes in human brain.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Localization of DJ-1 mRNA in the mouse brain.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Pathological properties of the Parkinson's disease-associated protein DJ-1 in alpha-synucleinopathies and tauopathies: relevance for multiple system atrophy and Pick's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

DJ-1 mutations are a rare cause of recessively inherited early onset parkinsonism mediated by loss of protein function

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

DJ-1 colocalizes with tau inclusions: a link between parkinsonism and dementia.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

The role of pathogenic DJ-1 mutations in Parkinson's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

The DJ-1L166P mutant protein associated with early onset Parkinson's disease is unstable and forms higher-order protein complexes

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783860

Localization of DJ-1 protein in the murine brain

2 September 2018

1 reference

12 December 2020

Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1

1 reference

12 December 2020

Destabilization of DJ-1 by familial substitution and oxidative modifications: implications for Parkinson's disease

1 reference

12 December 2020

DJ-1 (PARK7) is associated with 3R and 4R tau neuronal and glial inclusions in neurodegenerative disorders

1 reference

12 December 2020

Paraquat induces dopaminergic dysfunction and proteasome impairment in DJ-1-deficient mice

1 reference

12 December 2020

10.1016/J.BRAINRES.2008.09.009

Identifiers

DOI

1 reference

20 August 2017

1 reference

20 August 2017

1 reference