Multi-faceted role of HSP40 in cancer (Q37429975)

20 August 2017

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title

Multi-faceted role of HSP40 in cancer (English)

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20 August 2017

Aparna Mitra

1

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PubMed ID

19340594

20 August 2017

Lalita A Shevde

series ordinal

2

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PubMed ID

19340594

20 August 2017

Rajeev S Samant

series ordinal

3

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20 August 2017

2 April 2009

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Clinical & Experimental Metastasis

20 August 2017

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20 August 2017

26

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20 August 2017

6

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20 August 2017

559-567

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https://scigraph.springernature.com/pub.10.1007/s10585-009-9255-x

20 August 2017

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Enumeration of the simian virus 40 early region elements necessary for human cell transformation

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Role of the heat shock response and molecular chaperones in oncogenesis and cell death

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Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer.

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Phase II and pharmacodynamic study of the farnesyltransferase inhibitor R115777 as initial therapy in patients with metastatic pancreatic adenocarcinoma

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Simian virus 40 T antigens and J domains: analysis of Hsp40 cochaperone functions in Escherichia coli

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Autoantibody to heat shock protein Hsp40 in sera of lung cancer patients

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Tid1 isoforms are mitochondrial DnaJ-like chaperones with unique carboxyl termini that determine cytosolic fate

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Expression of the estrogen receptor-associated immunophilins, cyclophilin 40 and FKBP52, in breast cancer

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Heat shock protein 90: the cancer chaperone

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Hypothermia causes a reversible, p53-mediated cell cycle arrest in cultured fibroblasts

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Apoptosis, mitosis and cyclophilin-40 expression in regressing peroxisome proliferator-induced adenomas

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Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription

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12 December 2020

Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival

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Hsp90: a novel target for the disruption of multiple signaling cascades

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The immunophilin ligands cyclosporin A and FK506 suppress prostate cancer cell growth by androgen receptor-dependent and -independent mechanisms

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The diversity of the DnaJ/Hsp40 family, the crucial partners for Hsp70 chaperones

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12 December 2020

Molecular chaperone function of the SV40 large T antigen.

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12 December 2020

The metastatic process: basic research and clinical implications

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The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

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Dissemination and growth of cancer cells in metastatic sites

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12 December 2020

Tid1 negatively regulates the migratory potential of cancer cells by inhibiting the production of interleukin-8.

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12 December 2020

Chaperones as integrators of cellular networks: changes of cellular integrity in stress and diseases

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Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders

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Depletion of physiological levels of the human TID1 protein renders cancer cell lines resistant to apoptosis mediated by multiple exogenous stimuli

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12 December 2020

Stress kinases and heat shock proteins in the pancreas: possible roles in normal function and disease

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Not all J domains are created equal: implications for the specificity of Hsp40-Hsp70 interactions

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Anti-cancer therapeutic approaches based on intracellular and extracellular heat shock proteins

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12 December 2020

Exchangeable chaperone modules contribute to specification of type I and type II Hsp40 cellular function

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The small heat shock proteins and their role in human disease.

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Cardiac mitochondrial complex activity is enhanced by heat shock proteins.

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A phase I and pharmacological study of the farnesyl protein transferase inhibitor L-778,123 in patients with solid malignancies.

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Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours.

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Transcriptomic changes in human breast cancer progression as determined by serial analysis of gene expression

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12 December 2020

A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma

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12 December 2020

Chaperones in preventing protein denaturation in living cells and protecting against cellular stress

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12 December 2020

Re: Role of the heat shock response and molecular chaperones in oncogenesis and cell death.

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12 December 2020

Involvement of stress proteins in renal diseases

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12 December 2020

hTid-1, a human DnaJ protein, modulates the interferon signaling pathway

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12 December 2020

Protein quality control: triage by chaperones and proteases

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12 December 2020

Upregulation of the cochaperone Mdg1 in endothelial cells is induced by stress and during in vitro angiogenesis

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12 December 2020

Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone

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12 December 2020

JDP1 (DNAJC12/Hsp40) expression in breast cancer and its association with estrogen receptor status.

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12 December 2020

Molecular chaperones in cellular protein folding

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12 December 2020

Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models

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12 December 2020

TID1, a human homolog of the Drosophila tumor suppressor l(2)tid, encodes two mitochondrial modulators of apoptosis with opposing functions

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12 December 2020

Tid1, the human homologue of a Drosophila tumor suppressor, reduces the malignant activity of ErbB-2 in carcinoma cells

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12 December 2020

A phase I, pharmacokinetic, and biological study of the farnesyltransferase inhibitor tipifarnib in combination with gemcitabine in patients with advanced malignancies

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12 December 2020

Metastasis suppressor pathways--an evolving paradigm.

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12 December 2020

HDJ-2 as a target for radiosensitization of glioblastoma multiforme cells by the farnesyltransferase inhibitor R115777 and the role of the p53/p21 pathway

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12 December 2020

Hsp70 and Hsp90--a relay team for protein folding

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12 December 2020

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12 December 2020

Heat shock proteins in health and disease

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12 December 2020

Molecular mechanism of hTid-1, the human homolog of Drosophila tumor suppressor l(2)Tid, in the regulation of NF-kappaB activity and suppression of tumor growth

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12 December 2020

Progression of colorectal cancers correlates with overexpression and loss of polarization of expression of the htid-1 tumor suppressor.

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12 December 2020

High-throughput genomic technology in research and clinical management of breast cancer. Molecular signatures of progression from benign epithelium to metastatic breast cancer

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12 December 2020

Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature

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12 December 2020

The heat-shock response

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12 December 2020

High expression of shMDG1 gene is associated with low metastatic potential of tumor cells.

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12 December 2020

Understanding human cancer using Drosophila: Tid47, a cytosolic product of the DnaJ-like tumor suppressor gene l2Tid, is a novel molecular partner of patched related to skin cancer

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12 December 2020

HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain

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12 December 2020

Heat shock proteins as cellular lifeguards

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12 December 2020

NMR structure of the J-domain and the Gly/Phe-rich region of the Escherichia coli DnaJ chaperone

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12 December 2020

Allelic loss of cyclophilin 40, an estrogen receptor-associated immunophilin, in breast carcinomas

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12 December 2020

Roles of the heat shock transcription factors in regulation of the heat shock response and beyond

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12 December 2020

Thermally induced injury and heat-shock protein expression in cells and tissues

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12 December 2020

TID1, a mammalian homologue of the drosophila tumor suppressor lethal(2) tumorous imaginal discs, regulates activation-induced cell death in Th2 cells

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12 December 2020

Role of the protein chaperone YDJ1 in establishing Hsp90-mediated signal transduction pathways

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12 December 2020

Regulation of the Hsp90-binding immunophilin, cyclophilin 40, is mediated by multiple sites for GA-binding protein (GABP).

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12 December 2020

Mechanisms for regulation of Hsp70 function by Hsp40

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12 December 2020

Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40

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12 December 2020

Transient ectopic expression as a method to detect genes conferring drug resistance.

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12 December 2020

Does SV40 infection contribute to the development of human cancers?

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12 December 2020

Role of heat shock transcriptional factor 1 and heat shock proteins in cardiac hypertrophy

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12 December 2020

Heat shock proteins as novel therapeutic targets in cancer.

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12 December 2020

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12 December 2020

Global analysis of gene expression in invasion by a lung cancer model.

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12 December 2020

Heat shock proteins as emerging therapeutic targets

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12 December 2020

Molecular basis of invasion in breast cancer.

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12 December 2020

SV40 and human cancer: a review of recent data

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12 December 2020

Is there a role for SV40 in human cancer?

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12 December 2020

Extracellular heat shock protein 90: a role for a molecular chaperone in cell motility and cancer metastasis

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12 December 2020

Methylation-controlled J protein promotes c-Jun degradation to prevent ABCB1 transporter expression

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12 December 2020

Identification of a hTid-1 mutation which sensitizes gliomas to apoptosis.

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12 December 2020

Synergistic activation of the tumor suppressor, HLJ1, by the transcription factors YY1 and activator protein 1.

1 reference

12 December 2020

Curcumin inhibits lung cancer cell invasion and metastasis through the tumor suppressor HLJ1.

1 reference

12 December 2020

The N-terminal 178-amino-acid domain only of the SV40 large T antigen acts as a transforming suppressor of the HER-2/neu oncogene.

1 reference

12 December 2020

Hsp70 chaperones: cellular functions and molecular mechanism

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12 December 2020

Functional genetic screen for genes involved in senescence: role of Tid1, a homologue of the Drosophila tumor suppressor l(2)tid, in senescence and cell survival

1 reference

12 December 2020

Multiple sequence alignment with hierarchical clustering

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12 December 2020

Hold 'em and fold 'em: chaperones and signal transduction

1 reference

12 December 2020

The N-terminal domain of SV40 large T antigen represses the HER2/neu-mediated transformation and metastatic potential in breast cancers.

1 reference

12 December 2020

Interaction of the human DnaJ homologue, HSJ1b with the 90 kDa heat shock protein, Hsp90

1 reference

12 December 2020

SV40 in human brain cancers and non-Hodgkin's lymphoma

1 reference

12 December 2020

10.1007/S10585-009-9255-X

Identifiers

DOI

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20 August 2017

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PubMed ID

19340594