Immunomodulatory responses of peripheral blood mononuclear cells from multiple sclerosis patients upon in vitro incubation with the flavonoid luteolin: additive effects of IFN-beta (Q37402058)

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scientific article published on 13 October 2009

Language	Label	Description	Also known as
English	Immunomodulatory responses of peripheral blood mononuclear cells from multiple sclerosis patients upon in vitro incubation with the flavonoid luteolin: additive effects of IFN-beta	scientific article published on 13 October 2009

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Immunomodulatory responses of peripheral blood mononuclear cells from multiple sclerosis patients upon in vitro incubation with the flavonoid luteolin: additive effects of IFN-beta (English)

1 reference

Europe PubMed Central

20 August 2017

multiple sclerosis

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Bianca Weinstock-Guttman

6

object named as

Bianca Weinstock-Guttman

1 reference

Europe PubMed Central

20 August 2017

object named as

Allison Drake

4

0 references

author name string

Zohara Sternberg

1

1 reference

Europe PubMed Central

20 August 2017

Kailash Chadha

2

1 reference

Europe PubMed Central

20 August 2017

Alicia Lieberman

3

1 reference

Europe PubMed Central

20 August 2017

David Hojnacki

5

1 reference

Europe PubMed Central

20 August 2017

Frederick Munschauer

7

1 reference

Europe PubMed Central

20 August 2017

publication date

13 October 2009

1 reference

Europe PubMed Central

20 August 2017

Journal of Neuroinflammation

1 reference

Europe PubMed Central

20 August 2017

6

1 reference

Europe PubMed Central

20 August 2017

28

1 reference

Europe PubMed Central

20 August 2017

https://scigraph.springernature.com/pub.10.1186/1742-2094-6-28

0 references

Examining the evidence: complementary adjunctive therapies for multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Anthocyanins and their role in cancer prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Recent advances in the neuropathology of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Pathogenesis of myelin/oligodendrocyte damage in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative diseases.

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6 September 2017

Chemokines and matrix metalloproteinase-9 in leukocyte recruitment to the central nervous system.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Matrix metalloproteinases and neuroinflammation in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Acute stress increases permeability of the blood-brain-barrier through activation of brain mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Luteolin inhibits an endotoxin-stimulated phosphorylation cascade and proinflammatory cytokine production in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

6 September 2017

Macrophage as a target of quercetin glucuronides in human atherosclerotic arteries: implication in the anti-atherosclerotic mechanism of dietary flavonoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

14 September 2017

Quercetin 3-O-beta-(2''-galloyl)-glucopyranoside inhibits endotoxin LPS-induced IL-6 expression and NF-kappa B activation in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

14 September 2017

Luteolin inhibits insulin-like growth factor 1 receptor signaling in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

14 September 2017

Human mast cells release Interleukin-8 and induce neutrophil chemotaxis on contact with activated T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

14 September 2017

Flavonoids differentially modulate nitric oxide production pathways in lipopolysaccharide-activated RAW264.7 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

14 September 2017

Yin zi huang, an injectable multicomponent chinese herbal medicine, is a potent inhibitor of T-cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

14 September 2017

Flavonoids inhibit myelin phagocytosis by macrophages; a structure-activity relationship study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

14 September 2017

Quercetin suppresses proinflammatory cytokines production through MAP kinases andNF-kappaB pathway in lipopolysaccharide-stimulated macrophage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

14 September 2017

Luteolin inhibits myelin basic protein-induced human mast cell activation and mast cell-dependent stimulation of Jurkat T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

28 September 2017

Inhibition of LPS-stimulated pathways in macrophages by the flavonoid luteolin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

28 September 2017

Oral flavonoids delay recovery from experimental autoimmune encephalomyelitis in SJL mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

26 June 2018

The flavonoid luteolin prevents lipopolysaccharide-induced NF-kappaB signalling and gene expression by blocking IkappaB kinase activity in intestinal epithelial cells and bone-marrow derived dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

26 June 2018

Flavonoids influence monocytic GTPase activity and are protective in experimental allergic encephalitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

26 June 2018

Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

26 June 2018

Structural basis for antiviral activity of flavonoids-naturally occurring compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

26 June 2018

Toxicity and carcinogenicity studies of quercetin, a natural component of foods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

26 June 2018

Quercetin and interferon-beta modulate immune response(s) in peripheral blood mononuclear cells isolated from multiple sclerosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Effect of flavonoids on rat splenocytes, a structure-activity relationship study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Luteolin protects rat PC12 and C6 cells against MPP+ induced toxicity via an ERK dependent Keap1-Nrf2-ARE pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Modulation of interleukin-1beta mediated inflammatory response in human astrocytes by flavonoids: implications in neuroprotection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Cerebrospinal fluid and serum levels and intrathecal production of active matrix metalloproteinase-9 (MMP-9) as markers of disease activity in patients with multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Inhibition of collagenase by naturally-occurring flavonoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Production of cytokine and NO by RAW 264.7 macrophages and PBMC in vitro incubation with flavonoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Inhibition of matrix metalloproteinase-2 and -9 activities by selected flavonoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

The flavones luteolin and apigenin inhibit in vitro antigen-specific proliferation and interferon-gamma production by murine and human autoimmune T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Intracellular signalings underlying bradykinin-induced matrix metalloproteinase-9 expression in rat brain astrocyte-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

RhoA and Rac1 signals in fMLP-induced NF-kappaB activation in human blood monocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Cell culture protection and in vivo neuroprotective capacity of flavonoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Characteristic rat tissue accumulation of nobiletin, a chemopreventive polymethoxyflavonoid, in comparison with luteolin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Deglucuronidation of a flavonoid, luteolin monoglucuronide, during inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

T-cell- and macrophage-mediated axon damage in the absence of a CNS-specific immune response: involvement of metalloproteinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

2 September 2018

Serum MMP-9/TIMP-1 and MMP-2/TIMP-2 ratios in multiple sclerosis: relationships with different magnetic resonance imaging measures of disease activity during IFN-beta-1a treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768691

3 December 2018

Human mast cells stimulate activated T cells: implications for multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunomodulating Effects of Flavonoids on Acute and Chronic Inflammatory Responses Caused by Tumor Necrosis Factor α

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of aggregation and secretion of human platelets by quercetin and other flavonoids: structure-activity relationships

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic fate of luteolin and its functional activity at focal site

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Supplementation with quercetin markedly increases plasma quercetin concentration without effect on selected risk factors for heart disease in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioavailability of the dietary antioxidant flavonol quercetin in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scavenging of peroxynitrite-derived radicals by flavonoids may support endothelial NO synthase activity, contributing to the vascular protection associated with high fruit and vegetable intakes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutralizing antibodies and efficacy of interferon beta-1a: a 4-year controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-2094-6-28

1 reference

Europe PubMed Central

20 August 2017

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0 references

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

ResearchGate publication ID

0 references

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