Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA. (Q37396238)

20 August 2017

Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA. (English)

1 reference

20 August 2017

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5

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4 June 2020

author name string

Emmanuelle Despras

1

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4 June 2020

Méghane Sittewelle

2

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4 June 2020

Caroline Pouvelle

3

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4 June 2020

Noémie Delrieu

4

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4 June 2020

Patricia L Kannouche

6

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4 June 2020

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English

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publication date

4 November 2016

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20 August 2017

Nature Communications

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volume

7

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4 June 2020

page(s)

13326

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Creative Commons Attribution 4.0 International

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ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis

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The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells

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DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis

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TrxG and PcG proteins but not methylated histones remain associated with DNA through replication

6 September 2017

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Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions

6 September 2017

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Y-family DNA polymerases and their role in tolerance of cellular DNA damage.

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Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double strand breaks

6 September 2017

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6 September 2017

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Replication stress induces 53BP1-containing OPT domains in G1 cells

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6 September 2017

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Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication

6 September 2017

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CRL4(Cdt2) E3 ubiquitin ligase monoubiquitinates PCNA to promote translesion DNA synthesis

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Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Human DNA polymerase eta activity and translocation is regulated by phosphorylation

6 September 2017

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Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

6 September 2017

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Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks

6 September 2017

1 reference

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Human RAD18 is involved in S phase-specific single-strand break repair without PCNA monoubiquitination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Replication-dependent and -independent responses of RAD18 to DNA damage in human cells

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

SUMOsp: a web server for sumoylation site prediction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

SUMO: a history of modification

6 September 2017

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Differential regulation of Rad18 through Rad6-dependent mono- and polyubiquitination

6 September 2017

1 reference

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Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Ubiquitination of PCNA and the polymerase switch in human cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Protein modification by SUMO

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Mechanisms of accurate translesion synthesis by human DNA polymerase eta

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Impaired translesion synthesis in xeroderma pigmentosum variant extracts

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol η in response to oxidative DNA damage in human cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Regulation of translesion synthesis DNA polymerase eta by monoubiquitination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

PCNA ubiquitination and REV1 define temporally distinct mechanisms for controlling translesion synthesis in the avian cell line DT40.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Role of DNA polymerase eta in the UV mutation spectrum in human cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Aberrant C-terminal domain of polymerase η targets the functional enzyme to the proteosomal degradation pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

Human DNA polymerase eta is required for common fragile site stability during unperturbed DNA replication

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

The influence of caffeine on cell survival in excision-proficient and excision-deficient xeroderma pigmentosum and normal human cell strains following ultraviolet-light irradiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

FANCD2 binds MCM proteins and controls replisome function upon activation of s phase checkpoint signaling.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5097173

DNA–protein crosslink repair: proteases as DNA repair enzymes

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS13326

New strategy for the construction of single-stranded plasmids with single mutagenic lesions

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27811911

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS13326

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27811911%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 June 2020

ADS bibcode

2016NatCo...713326D

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27811911%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference