Prodrugs of thyrotropin-releasing hormone and related peptides as central nervous system agents (Q37391961)

20 August 2017

8 references

6 August 2019

12 September 2019

10 October 2019

17 November 2019

20 November 2019

19 December 2019

16 October 2020

15 July 2021

Prodrugs of thyrotropin-releasing hormone and related peptides as central nervous system agents (English)

1 reference

pharmaceutical preparation

20 August 2017

1 reference

6 August 2019

1 reference

12 September 2019

1 reference

10 October 2019

1 reference

17 November 2019

1 reference

20 November 2019

1 reference

19 December 2019

central nervous system agent

1 reference

16 October 2020

1 reference

15 July 2021

Katalin Prokai-Tatrai

series ordinal

1

1 reference

PubMed ID

19214153

20 August 2017

Laszlo Prokai

series ordinal

2

1 reference

PubMed ID

19214153

20 August 2017

language of work or name

English

0 references

publication date

6 February 2009

9 references

20 August 2017

6 August 2019

12 September 2019

10 October 2019

17 November 2019

20 November 2019

19 December 2019

16 October 2020

15 July 2021

9 references

20 August 2017

6 August 2019

12 September 2019

10 October 2019

17 November 2019

20 November 2019

19 December 2019

16 October 2020

15 July 2021

14

1 reference

20 August 2017

2

1 reference

20 August 2017

633-654

1 reference

Creative Commons Attribution

20 August 2017

8 references

6 August 2019

12 September 2019

10 October 2019

17 November 2019

20 November 2019

19 December 2019

16 October 2020

15 July 2021

0 references

Peptidases, peptides, and the mammalian blood-brain barrier

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Brain microvascular P-glycoprotein and a revised model of multidrug resistance in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

The impact of efflux transporters in the brain on the development of drugs for CNS disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Brain drug delivery technologies: novel approaches for transporting therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Blood-brain barrier delivery of protein and non-viral gene therapeutics with molecular Trojan horses

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Barriers to carrier mediated drug and gene delivery to brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Current prodrug strategies via membrane transporters/receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Blood-brain barrier biology and methodology

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Determinants of passive drug entry into the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Peptides and the blood-brain barrier: lipophilicity as a predictor of permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Hydrophobicity and central nervous system agents: on the principle of minimal hydrophobicity in drug design.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Acyloxyalkoxy-based cyclic prodrugs of opioid peptides: evaluation of the chemical and enzymatic stability as well as their transport properties across Caco-2 cell monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

The blood-brain barrier: principles for targeting peptides and drugs to the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Metabolism-based brain-targeting system for a thyrotropin-releasing hormone analogue.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Targeting drugs to the brain by redox chemical delivery systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Site-specific, sustained release of drugs to the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Permeability of the blood-cerebrospinal fluid and blood-brain barriers to thyrotropin-releasing hormone.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Isolation of thyrotropin releasing factor (TRF) from porcine hypothalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

The identity of chemical and hormonal properties of the thyrotropin releasing hormone and pyroglutamyl-histidyl-proline amide

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Thyrotrophin releasing hormone: endocrine and central effects

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Role of TRH receptors as possible mediators of analeptic actions of TRH-like peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

TRH and its novel analog (DN-1417): antipentobarbital action and involvement of cholinergic mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Metabolism and excretion of exogenous thyrotropin-releasing hormone in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Kinetic investigation of the specificity of porcine brain thyrotropin-releasing hormone-degrading ectoenzyme for thyrotropin-releasing hormone-like peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Valproate modulates TRH receptor, TRH and TRH-like peptide levels in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Identification of a mammalian glutaminyl cyclase converting glutaminyl into pyroglutamyl peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Dipeptidyl peptidase IV, a kidney brush-border serine peptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Brain-targeted delivery of a leucine-enkephalin analogue by retrometabolic design.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

The utility of oligopeptidase in brain-targeting delivery of an enkephalin analogue by prodrug design

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Neural differentiation of the human neuroblastoma cell line IMR32 induces production of a thyrotropin-releasing hormone-like peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Prodrugs to enhance central nervous system effects of the TRH-like peptide pGlu-Glu-Pro-NH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Immobilized-artificial-membrane chromatography: measurements of membrane partition coefficient and predicting drug membrane permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Immobilized artificial membrane chromatography coupled with atmospheric pressure ionization mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Integration of mass spectrometry into early-phase discovery and development of central nervous system agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Simple Method of Calculating Octanol/Water Partition Coefficient

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Synthetic thyrotropin-releasing factor analogs. 3. Effect of replacement or modification of histidine residue on biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Design, synthesis, and biological evaluation of novel, centrally-acting thyrotropin-releasing hormone analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Centrally acting and metabolically stable thyrotropin-releasing hormone analogues by replacement of histidine with substituted pyridinium.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Octanol-water partition of nonzwitterionic peptides: predictive power of a molecular size-based model

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Neuropharmacodynamic evaluation of the centrally active thyrotropin-releasing hormone analogue [Leu2]TRH and its chemical brain-targeting system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Depression: a new animal model sensitive to antidepressant treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

Chemical Aspects of Selective Toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14020633

The biology of pro-thyrotropin-releasing hormone-derived peptides

21 January 2018

1 reference

12 December 2020

A novel peptide, pyroglutamylglutamylproline amide, in the rabbit prostate complex, structurally related to thyrotrophin-releasing hormone

1 reference

12 December 2020

Structural and functional aspects of the blood-brain barrier.

1 reference

12 December 2020

A pyridinium-substituted analog of the TRH-like tripeptide pGlu-Glu-Pro-NH2 and its prodrugs as central nervous system agents

1 reference

12 December 2020

Human blood-brain barrier insulin receptor

1 reference

12 December 2020

Effects of thyrotropine releasing hormone (TRH) on pentobarbital-induced decrease in cholinergic neuronal activity

1 reference

12 December 2020

Taltirelin (Tanabe Seiyaku).

1 reference

12 December 2020

Electroconvulsive seizures modulate levels of thyrotropin releasing hormone and related peptides in rat hypothalamus, cingulate and lateral cerebellum

1 reference

12 December 2020

Hydrogen-bonding. Part 36. Determination of blood brain distribution using octanol-water partition coefficients.

1 reference

12 December 2020

On the Half Life of Thyrotropin-Releasing Hormone in Rats

1 reference

12 December 2020

Functional involvement of P-glycoprotein in blood-brain barrier

1 reference

12 December 2020

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

12 December 2020

TRH increases cerebrospinal fluid concentration of kynurenine

1 reference

12 December 2020

Synthesis of thyrotropin-releasing hormone analogues. 1. Complete dissociation of central nervous system effects from thyrotropin-releasing activity

1 reference

12 December 2020

Altering the properties of the blood-brain barrier: disruption and permeabilization

1 reference

12 December 2020

Effects of thyrotropin-releasing hormone (TRH) on the actions of pentobarbital and other centrally acting drugs

1 reference

12 December 2020

10.3390/MOLECULES14020633

Identifiers

DOI

1 reference

20 August 2017

0 references

1 reference

PubMed ID

19214153