Development and evaluation of a population pharmacokinetic-pharmacodynamic model of darbepoetin alfa in patients with nonmyeloid malignancies undergoing multicycle chemotherapy (Q37385389)

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scientific article published on September 2006

Language	Label	Description	Also known as
English	Development and evaluation of a population pharmacokinetic-pharmacodynamic model of darbepoetin alfa in patients with nonmyeloid malignancies undergoing multicycle chemotherapy	scientific article published on September 2006

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Development and evaluation of a population pharmacokinetic-pharmacodynamic model of darbepoetin alfa in patients with nonmyeloid malignancies undergoing multicycle chemotherapy (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

darbepoetin alfa

0 references

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

author name string

Balaji Agoram

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Anne C Heatherington

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Marc R Gastonguay

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

language of work or name

0 references

publication date

1 September 2006

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

The AAPS Journal

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

E552-63

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

https://scigraph.springernature.com/pub.10.1208/aapsj080364

0 references

Simultaneous vs. sequential analysis for population PK/PD data II: robustness of methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

Simultaneous vs. sequential analysis for population PK/PD data I: best-case performance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

Darbepoetin alfa has a longer circulating half-life and greater in vivo potency than recombinant human erythropoietin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

Comparison of stepwise covariate model building strategies in population pharmacokinetic-pharmacodynamic analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

Double-blind, placebo-controlled, randomized phase III trial of darbepoetin alfa in lung cancer patients receiving chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

Pharmacokinetics of novel erythropoiesis stimulating protein (NESP) in cancer patients: preliminary report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

Anaemia in cancer: pathophysiology and treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

Chemotherapy-induced anemia in adults: incidence and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

Comparison of four basic models of indirect pharmacodynamic responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

Modulating factors in the hematopoietic response to erythropoietin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

The pharmacokinetics and pharmacodynamics of recombinant human erythropoietin in haemodialysis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

6 September 2017

Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

14 September 2017

A mathematical model of erythropoiesis in mice and rats. Part 1: Structure of the model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

28 September 2017

Pharmacokinetics and pharmacodynamics of darbepoetin alfa and epoetin in patients undergoing dialysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

26 June 2018

Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: results of a randomized, double-blind, placebo-controlled trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

26 June 2018

Stability and performance of a population pharmacokinetic model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

26 June 2018

A mathematical model of erythropoiesis in mice and rats. Part 3: Suppressed erythropoiesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

26 June 2018

A mathematical model of erythropoiesis in mice and rats. Part 2: Stimulated erythropoiesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

26 June 2018

Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after multiple subcutaneous doses in healthy subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

2 September 2018

Effects of chemotherapy on endogenous erythropoietin levels and the pharmacokinetics and erythropoietic response of darbepoetin alfa: a randomised clinical trial of synchronous versus asynchronous dosing of darbepoetin alfa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

2 September 2018

Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after single and multiple doses in healthy volunteers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

2 September 2018

A randomized controlled trial of darbepoetin alfa administered as a fixed or weight-based dose using a front-loading schedule in patients with anemia who have nonmyeloid malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

2 September 2018

Clinical trial simulation of a 200-microg fixed dose of darbepoetin alfa in chemotherapy-induced anemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

2 September 2018

Changes in erythropoietin pharmacokinetics following busulfan-induced bone marrow ablation in sheep: evidence for bone marrow as a major erythropoietin elimination pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

2 September 2018

Basic pharmacodynamic models for agents that alter production of natural cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

2 September 2018

Prediction of response to treatment with recombinant human erythropoietin in anaemia associated with cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

2 September 2018

Hematopoietic model with moving boundary condition and state dependent delay: applications in erythropoiesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2761062

2 September 2018

A pharmacodynamic analysis of erythropoietin-stimulated reticulocyte response in phlebotomized sheep

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after intravenous and subcutaneous dose administration in cynomolgus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Breast cancer trial with erythropoietin terminated unexpectedly

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Darbepoetin alfa administered every 3 weeks alleviates anaemia in patients with solid tumours receiving chemotherapy; results of a double-blind, placebo-controlled, randomised study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of hematologic effects and fatigue in cancer patients with chemotherapy-induced anemia given darbepoetin alfa every two weeks

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Power, selection bias and predictive performance of the Population Pharmacokinetic Covariate Model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythropoietin life span in rats with hypoplastic and hyperplastic bone marrows

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacodynamic model of erythropoietin therapy for uremic anemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early prediction of response to recombinant human erythropoietin in patients with the anemia of renal failure by serum transferrin receptor and fibrinogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

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Models of schedule dependent haematological toxicity of 2'-deoxy-2'-methylidenecytidine (DMDC)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17025273

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1208/AAPSJ080364

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

0 references

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