Notch3 drives development and progression of cholangiocarcinoma. (Q37379639)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791012%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

title

Notch3 drives development and progression of cholangiocarcinoma (English)

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26 March 2020

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26 March 2020

Alexander Raven

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26 March 2020

Benjamin J Dwyer

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26 March 2020

Tim J Kendall

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26 March 2020

Wei-Yu Lu

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Jennifer P. Morton

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26 March 2020

Owen J Sansom

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26 March 2020

Stuart J Forbes

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Tania Roskams

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26 March 2020

author name string

Rachel V Guest

1

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26 March 2020

Tak-Yung Man

5

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26 March 2020

Sarah E Minnis-Lyons

6

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26 March 2020

Andrew J Robson

8

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Sofia Ferreira Gonzalez

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26 March 2020

Davina Wojtacha

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Mina Komuta

13

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26 March 2020

Stephen J Wigmore

15

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26 March 2020

language of work or name

English

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publication date

10 October 2016

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Proceedings of the National Academy of Sciences of the United States of America

26 March 2020

published in

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26 March 2020

volume

113

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26 March 2020

issue

43

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26 March 2020

page(s)

12250-12255

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Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

26 March 2020

cites work

1 reference

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Hepatic progenitor cells of biliary origin with liver repopulation capacity

6 September 2017

1 reference

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Non-canonical notch signaling in cancer and immunity

6 September 2017

1 reference

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Bipotential adult liver progenitors are derived from chronically injured mature hepatocytes

6 September 2017

1 reference

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Differential effects of targeting Notch receptors in a mouse model of liver cancer

6 September 2017

1 reference

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Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Combined targeting of AKT and mTOR using MK-2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Cholangiocarcinomas can originate from hepatocytes in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Jagged1 expression regulated by Notch3 and Wnt/β-catenin signaling pathways in ovarian cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

A CK19(CreERT) knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

p53 Mutations in human cholangiocarcinoma: a review

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Cell lineage tracing reveals a biliary origin of intrahepatic cholangiocarcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Two new human cholangiocarcinoma cell lines and their cytogenetics and responses to growth factors, hormones, cytokines or immunologic effector cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Notch1 and Notch4 are markers for poor prognosis of hepatocellular carcinoma

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

A critical role for notch signaling in the formation of cholangiocellular carcinomas.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Notch signaling controls liver development by regulating biliary differentiation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Thioacetamide-induced intestinal-type cholangiocarcinoma in rat: an animal model recapitulating the multi-stage progression of human cholangiocarcinoma

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086988

2 September 2018

Identifiers

DOI

10.1073/PNAS.1600067113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791012%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791012%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference