Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation. (Q37375092)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19549922%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation (English)

1 reference

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1 February 2020

1 reference

1 reference

3

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1 February 2020

7

Holly A Ingraham

1 reference

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1 February 2020

5

Serdar E Bulun

1 reference

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1 February 2020

author name string

Benjamin C Lin

1

1 reference

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1 February 2020

Miyuki Suzawa

2

1 reference

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1 February 2020

Sandra C Tobias

4

1 reference

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1 February 2020

Thomas S Scanlan

6

1 reference

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1 February 2020

language of work or name

English

0 references

publication date

23 June 2009

1 reference

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1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19549922%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

69

1 reference

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1 February 2020

issue

13

1 reference

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1 February 2020

page(s)

5415-5423

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Prostaglandin E2 via steroidogenic factor-1 coordinately regulates transcription of steroidogenic genes necessary for estrogen synthesis in endometriosis

1 February 2020

cites work

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Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

6 September 2017

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Androstenedione up-regulation of endometrial aromatase expression via local conversion to estrogen: potential relevance to the pathogenesis of endometriosis.

6 September 2017

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Association of the membrane estrogen receptor, GPR30, with breast tumor metastasis and transactivation of the epidermal growth factor receptor

6 September 2017

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Estrogen signaling through the transmembrane G protein-coupled receptor GPR30.

6 September 2017

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Tamoxifen: catalyst for the change to targeted therapy

6 September 2017

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GPR30 contributes to estrogen-induced thymic atrophy

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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A G-protein-coupled estrogen receptor is involved in hypothalamic control of energy homeostasis

6 September 2017

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A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer

6 September 2017

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6 September 2017

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A transmembrane intracellular estrogen receptor mediates rapid cell signaling

6 September 2017

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Integration of the extranuclear and nuclear actions of estrogen

6 September 2017

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Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

6 September 2017

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The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells.

6 September 2017

1 reference

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G protein-coupled receptor 30 is critical for a progestin-induced growth inhibition in MCF-7 breast cancer cells

6 September 2017

1 reference

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Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes

6 September 2017

1 reference

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Epidermal growth factor receptor (EGFR) transactivation by estrogen via the G-protein-coupled receptor, GPR30: a novel signaling pathway with potential significance for breast cancer

6 September 2017

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Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis

6 September 2017

1 reference

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Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary

6 September 2017

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Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF

6 September 2017

1 reference

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Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

6 September 2017

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Aromatase as a therapeutic target in endometriosis

6 September 2017

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Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress

6 September 2017

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Stimulation of aromatase P450 promoter (II) activity in endometriosis and its inhibition in endometrium are regulated by competitive binding of steroidogenic factor-1 and chicken ovalbumin upstream promoter transcription factor to the same cis-actin

6 September 2017

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Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer

6 September 2017

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Steroidogenic factor 1, an orphan nuclear receptor, regulates the expression of the rat aromatase gene in gonadal tissues

6 September 2017

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Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane.

6 September 2017

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G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells

14 September 2017

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Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption

14 September 2017

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17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30.

14 September 2017

1 reference

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Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.

14 September 2017

1 reference

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Gene expression profile for ectopic versus eutopic endometrium provides new insights into endometriosis oncogenic potential

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756996

Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756996

Liver receptor homolog-1 and steroidogenic factor-1 have similar actions on rat granulosa cell steroidogenesis.

2 September 2018

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Synthesis and biological evaluation of SERMs with potent nongenomic estrogenic activity

2 September 2018

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Nature of functional estrogen receptors at the plasma membrane.

2 September 2018

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Virtual and biomolecular screening converge on a selective agonist for GPR30.

2 September 2018

1 reference

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Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action

2 September 2018

1 reference

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The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells

2 September 2018

1 reference

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Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer

2 September 2018

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Rapid Signaling of Estrogen in Hypothalamic Neurons Involves a Novel G-Protein-Coupled Estrogen Receptor that Activates Protein Kinase C

2 September 2018

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Biochemical characterization of peritoneal fluid in women during the menstrual cycle

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19549922

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19549922

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

GPR30: a novel indicator of poor survival for endometrial carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19549922

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-08-1622

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19549922%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19549922%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

19549922

1 reference