Novel anti-Alzheimer's dimer Bis(7)-cognitin: cellular and molecular mechanisms of neuroprotection through multiple targets (Q37358683)

19 August 2017

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title

Novel anti-Alzheimer's dimer Bis(7)-cognitin: cellular and molecular mechanisms of neuroprotection through multiple targets (English)

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19 August 2017

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5

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19 August 2017

Yifan Han

7

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Chen Kaixian

6

object named as

Kaixian Chen

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19 August 2017

Wenming Li

1

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19 August 2017

Marvin Mak

2

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19 August 2017

Hualiang Jiang

3

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19 August 2017

Qinwen Wang

4

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19 August 2017

1 January 2009

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19 August 2017

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19 August 2017

6

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19 August 2017

1

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19 August 2017

187-201

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https://scigraph.springernature.com/pub.10.1016/j.nurt.2008.10.040

19 August 2017

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Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors

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14 September 2017

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14 September 2017

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14 September 2017

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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Bis(7)-tacrine, a promising anti-Alzheimer's dimer, affords dose- and time-dependent neuroprotection against transient focal cerebral ischemia

26 June 2018

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The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine

2 September 2018

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Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084266

Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels.

2 September 2018

1 reference

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Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

2 September 2018

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Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity.

2 September 2018

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Protection against ischemic injury in primary cultured mouse astrocytes by bis(7)-tacrine, a novel acetylcholinesterase inhibitor [corrected].

2 September 2018

1 reference

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Bis(7)-tacrine, a novel acetylcholinesterase inhibitor, reverses AF64A-induced deficits in navigational memory in rats.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084266

Attenuation of scopolamine-induced deficits in navigational memory performance in rats by bis(7)-tacrine, a novel dimeric AChE inhibitor.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084266

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084266

Soluble oligomers of amyloid-beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway

2 September 2018

1 reference

12 December 2020

Bis(7)-tacrine, a promising anti-Alzheimer's agent, reduces hydrogen peroxide-induced injury in rat pheochromocytoma cells: comparison with tacrine

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12 December 2020

Potent, easily synthesized huperzine A-tacrine hybrid acetylcholinesterase inhibitors

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12 December 2020

Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as

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12 December 2020

The structures of huperzine A and B, two new alkaloids exhibiting marked anticholinesterase activity

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.1139/V86-137

Identifiers

DOI

10.1016/J.NURT.2008.10.040

1 reference

release_otitkon7z5dalkj7x37hl346oy

19 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/otitkon7z5dalkj7x37hl346oy

24 November 2022

mapped directly with Wikidata item

1 reference

19 August 2017

1 reference