Developing neuroprotective strategies for treatment of HIV-associated neurocognitive dysfunction (Q37354387)

19 August 2017

Developing neuroprotective strategies for treatment of HIV-associated neurocognitive dysfunction (English)

1 reference

19 August 2017

0 references

3

Ned Sacktor

1 reference

19 August 2017

Jeffrey A Rumbaugh

1

1 reference

PMCID

2747312

19 August 2017

Joseph Steiner

series ordinal

2

1 reference

PMCID

2747312

19 August 2017

Avindra Nath

series ordinal

4

1 reference

19 August 2017

1 January 2008

1 reference

19 August 2017

1 reference

19 August 2017

2

1 reference

19 August 2017

3

1 reference

19 August 2017

271-280

1 reference

Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Updated research nosology for HIV-associated neurocognitive disorders

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Dementia and neurocognitive disorders due to HIV-1 infection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Neuroprotective effects of MTEP, a selective mGluR5 antagonists and neuropeptide Y on the kainate-induced toxicity in primary neuronal cultures.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Human lupus autoantibodies against NMDA receptors mediate cognitive impairment.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Valproic acid is associated with cognitive decline in HIV-infected individuals: a clinical observational study.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Novel modulators of poly(ADP-ribose) polymerase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

The role of neutralizing antibodies in HIV infection.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIV therapeutics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

On the horizon: promising investigational antiretroviral agents

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Developments in HIV neuropathogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

NXY-059: review of neuroprotective potential for acute stroke

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Neuroprotective and anti-human immunodeficiency virus activity of minocycline

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Neutralizing antibodies to disease-modifying agents in the treatment of multiple sclerosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Antiviral effects of human immunodeficiency virus type 1-specific small interfering RNAs against targets conserved in select neurotropic viral strains

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Neuroimmunophilins: a novel drug therapy for the reversal of neurodegenerative disease?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Blood-brain barrier changes during invasion of the central nervous system by HIV-1. Old and new insights into the mechanism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Human immunodeficiency virus-associated dementia: an evolving disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

The epidemiology of human immunodeficiency virus-associated neurological disease in the era of highly active antiretroviral therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Searching for clues: tracking the pathogenesis of human immunodeficiency virus central nervous system disease by use of an accelerated, consistent simian immunodeficiency virus macaque model

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

HIV-1 Tat protein induces interleukin-10 in human peripheral blood monocytes: involvement of protein kinase C-betaII and -delta

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

HIV neuropathy: insights in the pathology of HIV peripheral nerve disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Poly (ADP-ribose) polymerase, nitric oxide and cell death

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Therapy with minocycline aggravates experimental rabies in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Nitrone-based free radical traps as neuroprotective agents in cerebral ischaemia and other pathologies.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Brain CD8+ and cytotoxic T lymphocytes are associated with, and may be specific for, human immunodeficiency virus type 1 encephalitis in patients with acquired immunodeficiency syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Lithium improves HIV-associated neurocognitive impairment

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Potential neuroprotective effect of t-butylhydroquinone against neurotoxicity-induced by 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-methyl-MPTP) in mice

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

HIV infection of macrophages and pathogenesis of AIDS dementia complex: interaction of the host cell and viral genotype.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Early penetration of the blood-brain-barrier by HIV.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Early viral brain invasion in iatrogenic human immunodeficiency virus infection

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Changed levels of substance P and somatostatin in HIV-positive children

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

26 June 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Marked improvement in survival following AIDS dementia complex in the era of highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Increased detection of serum HHV-6 DNA sequences during multiple sclerosis (MS) exacerbations and correlation with parameters of MS disease progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Enhancing antiretroviral therapy for human immunodeficiency virus cognitive disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Oxidative stress in HIV demented patients and protection ex vivo with novel antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Reconstitution of human immunodeficiency virus-induced neurodegeneration using isolated populations of human neurons, astrocytes, and microglia and neuroprotection mediated by insulin-like growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3beta to antagonize nuclear factor-kappaB survival pathway in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Modulation of human immunodeficiency virus infection by anticonvulsant drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Inhibition of mixed lineage kinase 3 prevents HIV-1 Tat-mediated neurotoxicity and monocyte activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

A novel anti-inflammatory role for simvastatin in inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Hydroxymethylglutaryl coenzyme a reductase inhibitors down-regulate chemokines and chemokine receptors in patients with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Ceftriaxone protects against the neurotoxicity of human immunodeficiency virus proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

The immunophilin ligand GPI1046 protects neurons from the lethal effects of the HIV-1 proteins gp120 and Tat by modulating endoplasmic reticulum calcium load.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Neuroprotective effect of estradiol and phytoestrogens on MPP+-induced cytotoxicity in neuronal PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Stilbazulenyl nitrone, a novel antioxidant, is highly neuroprotective in focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Antibodies against a multiple-peptide conjugate comprising chemically modified human immunodeficiency virus type-1 functional Tat peptides inhibit infection

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Erythropoietin protects cerebrocortical neurons from HIV-1/gp120-induced damage

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17469600.2.3.271

Memantine upregulates BDNF and prevents dopamine deficits in SIV-infected macaques: a novel pharmacological action of memantine.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747312

Thioredoxin reductase and glutathione synthesis is upregulated by t-butylhydroquinone in cortical astrocytes but not in cortical neurons

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19774095

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Erythropoietin is neuroprotective in models of HIV sensory neuropathy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19774095

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

HIV-associated cognitive impairment before and after the advent of combination therapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19774095

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2217/17469600.2.3.271

1 reference

19 August 2017

1 reference

19 August 2017

1 reference

PMCID

2747312