Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways. (Q37353557)

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scientific article published on April 1996

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English	Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways.	scientific article published on April 1996

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scholarly article

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15 October 2019

Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways (English)

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15 October 2019

ubiquitin-proteasome system

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inferred from title

3

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15 October 2019

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15 October 2019

author name string

Voisin L

1

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Breuillé D

2

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15 October 2019

Pouyet C

4

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Taillandier D

5

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15 October 2019

Aurousseau E

6

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15 October 2019

Obled C

7

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1 April 1996

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15 October 2019

Journal of Clinical Investigation

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97

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15 October 2019

1610-1617

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15 October 2019

7

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15 October 2019

Metabolic acidosis stimulates muscle protein degradation by activating the adenosine triphosphate-dependent pathway involving ubiquitin and proteasomes

1 reference

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14-kDa ubiquitin-conjugating enzyme: structure of the rat gene and regulation upon fasting and by insulin

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6 September 2017

Sepsis stimulates nonlysosomal, energy-dependent proteolysis and increases ubiquitin mRNA levels in rat skeletal muscle

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6 September 2017

The ubiquitin-proteasome proteolytic pathway

1 reference

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Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging

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L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

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Inhibitors of prostaglandin synthesis or cathepsin B prevent muscle wasting due to sepsis in the rat

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Measurement of protein using bicinchoninic acid

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Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease

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In vitro proteolytic processing of a diubiquitin and a truncated diubiquitin formed from in vitro-generated mRNAs

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Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. A synergistic effect with interleukin 1

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cDNA cloning and sequencing of component C9 of proteasomes from rat hepatoma cells

1 reference

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6 September 2017

The pathogenesis of sepsis

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6 September 2017

Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture

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6 September 2017

The ubiquitin system for protein degradation

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6 September 2017

Endocrine regulation of protein breakdown in skeletal muscle.

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14 September 2017

Regulation of ATP-ubiquitin-dependent proteolysis in muscle wasting.

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14 September 2017

Proteolytic activity of proteasome on myofibrillar structures

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14 September 2017

Interleukin-6 induces skeletal muscle protein breakdown in rats

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28 September 2017

Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy

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Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting.

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Effect of parenteral nutrition on muscle amino acid output and 3-methylhistidine excretion in septic patients

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The effects of endotoxaemia on protein metabolism in skeletal muscle and liver of fed and fasted rats

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Production of hybridoma growth factor by human monocytes.

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26 June 2018

Total and myofibrillar protein breakdown in different types of rat skeletal muscle: effects of sepsis and regulation by insulin

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26 June 2018

cDNA cloning and sequencing of component C8 of proteasomes from rat hepatoma cells.

1 reference

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26 June 2018

Total and net muscle protein breakdown in infection determined by amino acid effluxes

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26 June 2018

Calcium-dependent and calcium-independent protease activities in skeletal muscle during sepsis

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26 June 2018

Gene expression of calpains and their specific endogenous inhibitor, calpastatin, in skeletal muscle of fed and fasted rabbits

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26 June 2018

Sepsis-induced changes in protein synthesis: differential effects on fast- and slow-twitch muscles

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26 June 2018

Proteolysis associated with a deficit of peripheral energy fuel substrates in septic man.

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26 June 2018

Pentoxifylline decreases body weight loss and muscle protein wasting characteristics of sepsis.

1 reference

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Tissue protein turnover is altered during catch-up growth following Escherichia coli infection in weanling rats.

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2 September 2018

Metabolic effects of infection.

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Role of different proteolytic systems in the degradation of muscle proteins during denervation atrophy

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A fluorometric method for the estimation of tyrosine in plasma and tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

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Influence of sepsis in rats on muscle protein turnover in vivo and in tissue incubated under different in vitro conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased ATP-ubiquitin-dependent proteolysis in skeletal muscles of tumor-bearing rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo administration of interleukin-1 alpha induces muscle proteolysis in normal and adrenalectomized rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour necrosis factor-α increases the ubiquitinization of rat skeletal muscle proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin gene expression is increased in skeletal muscle of tumour-bearing rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

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based on heuristic

inferred from PubMed ID database lookup

Muscle proteolysis induced by a circulating peptide in patients with sepsis or trauma

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein metabolism in different types of skeletal muscle during early and late sepsis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that cathepsin B contributes to skeletal muscle protein breakdown during sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of parenteral nutrition on protein turnover in endotoxaemic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of sepsis on calcium uptake and content in skeletal muscle and regulation in vitro by calcium of total and myofibrillar protein breakdown in control and septic muscle: results from a preliminary study

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the ATP-ubiquitin-proteasome pathway in skeletal muscle of cachectic rats bearing a hepatoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

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based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 induces proteolysis by activating intracellular proteases (cathepsins B and L, proteasome) in C2C12 myotubes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8601625

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based on heuristic

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Identifiers

10.1172/JCI118586

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Europe PubMed Central

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15 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8601625%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8601625%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

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