Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants (Q37352307)

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scientific article published on April 2008

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English	Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants	scientific article published on April 2008

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scholarly article

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Europe PubMed Central

19 August 2017

Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants (English)

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Europe PubMed Central

19 August 2017

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author name string

Patricia Cassina

1

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Europe PubMed Central

19 August 2017

Adriana Cassina

2

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Europe PubMed Central

19 August 2017

Mariana Pehar

3

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Europe PubMed Central

19 August 2017

Raquel Castellanos

4

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Europe PubMed Central

19 August 2017

Mandi Gandelman

5

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Europe PubMed Central

19 August 2017

Andrés de León

6

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Europe PubMed Central

19 August 2017

Kristine M Robinson

7

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Europe PubMed Central

19 August 2017

Ronald P Mason

8

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Europe PubMed Central

19 August 2017

Joseph S Beckman

9

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Europe PubMed Central

19 August 2017

Luis Barbeito

10

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Europe PubMed Central

19 August 2017

Rafael Radi

11

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Europe PubMed Central

19 August 2017

language of work or name

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publication date

1 April 2008

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19 August 2017

number of pages

8

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Journal of Neuroscience

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Europe PubMed Central

19 August 2017

28

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Europe PubMed Central

19 August 2017

16

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19 August 2017

4115-4122

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19 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3844766/fullTextXML

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Biochemistry of protein tyrosine nitration in cardiovascular pathology

1 reference

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Inhibition of mitochondrial function in astrocytes: implications for neuroprotection.

1 reference

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6 September 2017

Simple quantitative detection of mitochondrial superoxide production in live cells

1 reference

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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

1 reference

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Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria

1 reference

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Selective fluorescent imaging of superoxide in vivo using ethidium-based probes

1 reference

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Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria

1 reference

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1 reference

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Peroxynitrite reactions and formation in mitochondria

1 reference

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1 reference

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Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS

1 reference

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Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

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1 reference

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1 reference

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Mutant SOD1-induced neuronal toxicity is mediated by increased mitochondrial superoxide levels

1 reference

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Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis

1 reference

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Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis

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Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion.

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Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis

1 reference

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Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis

1 reference

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Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice.

1 reference

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1 reference

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Cytochrome c association with the inner mitochondrial membrane is impaired in the CNS of G93A-SOD1 mice.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

1 reference

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2 September 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844766

2 September 2018

Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis

1 reference

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2 September 2018

Cytochrome c nitration by peroxynitrite.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844766

2 September 2018

Upregulation of protein-tyrosine nitration in the anterior horn cells of amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844766

2 September 2018

Neurotrophins promote motor neuron survival and are present in embryonic limb bud.

1 reference

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2 September 2018

Detection of catalase in rat heart mitochondria

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https://pubmed.ncbi.nlm.nih.gov/18417691

12 December 2020

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Differential inhibitory action of nitric oxide and peroxynitrite on mitochondrial electron transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/18417691

12 December 2020

based on heuristic

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The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic

1 reference

https://pubmed.ncbi.nlm.nih.gov/18417691

12 December 2020

based on heuristic

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Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18417691

12 December 2020

based on heuristic

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Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18417691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18417691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of manganese porphyrins by flavoenzymes and submitochondrial particles: a catalytic cycle for the reduction of peroxynitrite

1 reference

https://pubmed.ncbi.nlm.nih.gov/18417691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18417691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18417691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18417691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5308-07.2008

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Europe PubMed Central

19 August 2017

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Europe PubMed Central

19 August 2017

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Europe PubMed Central

19 August 2017

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