Packaging and Prefusion Stabilization Separately and Additively Increase the Quantity and Quality of Respiratory Syncytial Virus (RSV)-Neutralizing Antibodies Induced by an RSV Fusion Protein Expressed by a Parainfluenza Virus Vector. (Q37347267)

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scientific article published on 31 August 2016

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English	Packaging and Prefusion Stabilization Separately and Additively Increase the Quantity and Quality of Respiratory Syncytial Virus (RSV)-Neutralizing Antibodies Induced by an RSV Fusion Protein Expressed by a Parainfluenza Virus Vector.	scientific article published on 31 August 2016

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scholarly article

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22 March 2020

Packaging and Prefusion Stabilization Separately and Additively Increase the Quantity and Quality of Respiratory Syncytial Virus (RSV)-Neutralizing Antibodies Induced by an RSV Fusion Protein Expressed by a Parainfluenza Virus Vector (English)

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vector-borne disease

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Jason S. McLellan

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Barney S. Graham

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Barney S Graham

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Peter D Kwong

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Nicolaas Schaap

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Emerito Amaro-Carambot

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Barbora Kabatova

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Natalie Mackow

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Matthias Lingemann

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Matthias Lingemann

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Anne Schaap-Nutt

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Joanna Swerczek

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Richard Herbert

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David W Dorward

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Lijuan Yang

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Man Chen

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Azad Kumar

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Peter L Collins

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14 October 2016

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Journal of Virology

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10022-10038

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21

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22 March 2020

A Recombinant Respiratory Syncytial Virus Vaccine Candidate Attenuated by a Low-Fusion F Protein Is Immunogenic and Protective against Challenge in Cotton Rats

1 reference

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6 September 2017

Sendai virus as a backbone for vaccines against RSV and other human paramyxoviruses

1 reference

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6 September 2017

Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068507

6 September 2017

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

1 reference

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6 September 2017

Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068507

6 September 2017

Enhanced Neutralizing Antibody Response Induced by Respiratory Syncytial Virus Prefusion F Protein Expressed by a Vaccine Candidate.

1 reference

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6 September 2017

Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genes

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Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization

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Chimeric bovine/human parainfluenza virus type 3 expressing respiratory syncytial virus (RSV) F glycoprotein: effect of insert position on expression, replication, immunogenicity, stability, and protection against RSV infection.

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Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

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Trimeric transmembrane domain interactions in paramyxovirus fusion proteins: roles in protein folding, stability, and function

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Respiratory syncytial virus modified by deletions of the NS2 gene and amino acid S1313 of the L polymerase protein is a temperature-sensitive, live-attenuated vaccine candidate that is phenotypically stable at physiological temperature

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Neutralizing antibodies against the preactive form of respiratory syncytial virus fusion protein offer unique possibilities for clinical intervention

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A critical phenylalanine residue in the respiratory syncytial virus fusion protein cytoplasmic tail mediates assembly of internal viral proteins into viral filaments and particles

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6 September 2017

The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unit

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6 September 2017

Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

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6 September 2017

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

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Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

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6 September 2017

Paramyxovirus assembly and budding: building particles that transmit infections

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The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenuated, respiratory syncytial virus vaccines

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Immunization of primates with a Newcastle disease virus-vectored vaccine via the respiratory tract induces a high titer of serum neutralizing antibodies against highly pathogenic avian influenza virus.

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The influence of antigen organization on B cell responsiveness

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https://pubmed.ncbi.nlm.nih.gov/27581977

12 December 2020

based on heuristic

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The impact of infection with human metapneumovirus and other respiratory viruses in young infants and children at high risk for severe pulmonary disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27581977

12 December 2020

based on heuristic

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10.1128/JVI.01196-16

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Europe PubMed Central

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22 March 2020

1 reference

Europe PubMed Central

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22 March 2020

1 reference

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22 March 2020

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