Differential effects of simvastatin and pravastatin on expression of Alzheimer's disease-related genes in human astrocytes and neuronal cells (Q37337494)

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scientific article published on 21 May 2009

Language	Label	Description	Also known as
English	Differential effects of simvastatin and pravastatin on expression of Alzheimer's disease-related genes in human astrocytes and neuronal cells	scientific article published on 21 May 2009

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Differential effects of simvastatin and pravastatin on expression of Alzheimer's disease-related genes in human astrocytes and neuronal cells (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Alzheimer's disease

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human astrocyte

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1 reference

based on heuristic

inferred from title

author name string

Weijiang Dong

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Simona Vuletic

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

John J Albers

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

publication date

21 May 2009

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Journal of Lipid Research

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

50

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

2095-2102

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

6 September 2017

Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

1 reference

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6 September 2017

Patients with Alzheimer's disease may be particularly susceptible to adverse effects of statins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

6 September 2017

Statin-associated memory loss: analysis of 60 case reports and review of the literature

1 reference

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6 September 2017

HDL apolipoproteins and ABCA1: partners in the removal of excess cellular cholesterol

1 reference

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6 September 2017

A clinical focus on statins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

6 September 2017

Statins and the risk of dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

6 September 2017

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

1 reference

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Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation

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6 September 2017

Apolipoprotein E and the response of the brain to injury

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6 September 2017

Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

6 September 2017

The association of apolipoprotein E polymorphism with memory: a population based study

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A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve

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6 September 2017

Expression of apolipoprotein E during nerve degeneration and regeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

6 September 2017

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation

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6 September 2017

Apolipoproteins in human cerebrospinal fluid

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6 September 2017

Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing.

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14 September 2017

Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease

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14 September 2017

Activation of mitogen-activated protein kinase by muscarinic receptors in astroglial cells: role in DNA synthesis and effect of ethanol

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28 September 2017

Fatty acid composition of brain phospholipids in aging and in Alzheimer's disease

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28 September 2017

Essential role for cholesterol in synaptic plasticity and neuronal degeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

26 June 2018

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

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26 June 2018

Lipid compositions of different regions of the human brain during aging.

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26 June 2018

Membrane lipids in the aging human brain.

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26 June 2018

Effects of apolipoprotein E, beta-very low density lipoproteins, and cholesterol on the extension of neurites by rabbit dorsal root ganglion neurons in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

26 June 2018

Investigating the potential neuroprotective effects of statins on DNA damage in mouse striatum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

2 September 2018

The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor lovastatin reduces severity of L-DOPA-induced abnormal involuntary movements in experimental Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

2 September 2018

Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

2 September 2018

Statins enhance toll-like receptor 4-mediated cytokine gene expression in astrocytes: implication of Rho proteins in negative feedback regulation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

2 September 2018

Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

2 September 2018

Statins of different brain penetrability differentially affect CSF PLTP activity.

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2 September 2018

Effects of apoE on neuronal signaling and APP processing in rodent brain.

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2 September 2018

Cholesterol deficiency perturbs actin signaling and glutamate homeostasis in hippocampal astrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

2 September 2018

ApoE isoform-specific effects on LTP: blockade by oligomeric amyloid-beta1-42.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

2 September 2018

Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

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Statin use and hippocampal volumes in elderly subjects at risk for Alzheimer's disease: a pilot observational study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

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ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

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2 September 2018

Cognitive impairment associated with atorvastatin and simvastatin

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Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease

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2 September 2018

Effects of statins on human cerebral cholesterol metabolism and secretion of Alzheimer amyloid peptide

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2 September 2018

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial

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2 September 2018

The impact of the use of statins on the prevalence of dementia and the progression of cognitive impairment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739764

2 September 2018

Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people.

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2 September 2018

Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brain

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2 September 2018

CNS synaptogenesis promoted by glia-derived cholesterol

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2 September 2018

Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide

2 references

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2 September 2018

https://api.crossref.org/works/10.1194%2FJLR.M900236-JLR200

21 January 2018

Simvastatin-associated memory loss

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2 September 2018

Memory deficits and cholinergic impairments in apolipoprotein E-deficient mice.

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2 September 2018

Membrane lipids of adult human brain: lipid composition of frontal and temporal lobe in subjects of age 20 to 100 years.

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2 September 2018

An in vitro study of the effects of lovastatin on human fetal brain cells

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12 December 2020

based on heuristic

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Plasma phospholipid mass transfer rate: relationship to plasma phospholipid and cholesteryl ester transfer activities and lipid parameters

1 reference

https://pubmed.ncbi.nlm.nih.gov/19461118

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between statin use and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19461118

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1194/JLR.M900236-JLR200

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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