New drugs in multiple myeloma: mechanisms of action and phase I/II clinical findings. (Q37336468)

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17 January 2020

review article

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title

New drugs in multiple myeloma: mechanisms of action and phase I/II clinical findings (English)

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17 January 2020

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1

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17 January 2020

Patricia Maiso

series ordinal

3

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17 January 2020

Jesús San Miguel

series ordinal

5

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17 January 2020

4

Atanasio Pandiella

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17 January 2020

author name string

María-Victoria Mateos

series ordinal

2

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17 January 2020

publication date

1 December 2008

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Lancet Oncology Commission

17 January 2020

published in

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17 January 2020

volume

9

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17 January 2020

page(s)

1157-1165

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17 January 2020

issue

12

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Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets

17 January 2020

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CHIR-258 is efficacious in a newly developed fibroblast growth factor receptor 3-expressing orthotopic multiple myeloma model in mice

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The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications

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GW654652, the pan-inhibitor of VEGF receptors, blocks the growth and migration of multiple myeloma cells in the bone marrow microenvironment

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The insulin-like growth factor-I receptor inhibitor NVP-AEW541 provokes cell cycle arrest and apoptosis in multiple myeloma cells.

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7 January 2021

Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu

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7 January 2021

Human anti-CD40 antagonist antibody triggers significant antitumor activity against human multiple myeloma

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7 January 2021

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

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7 January 2021

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

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7 January 2021

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7 January 2021

Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth

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7 January 2021

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7 January 2021

p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells

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7 January 2021

Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis

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7 January 2021

In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells.

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7 January 2021

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7 January 2021

10.1016/S1470-2045(08)70304-8

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19038762%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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