Therapeutic and prophylactic applications of alphavirus vectors (Q37322650)

19 August 2017

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title

Therapeutic and prophylactic applications of alphavirus vectors (English)

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19 August 2017

Brian J Sheahan

3

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author name string

Gregory J Atkins

series ordinal

1

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PubMed ID

19000329

19 August 2017

Marina N Fleeton

series ordinal

2

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19 August 2017

11 November 2008

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Expert Reviews in Molecular Medicine

19 August 2017

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19 August 2017

10

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19 August 2017

e33

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Oncolytic capacity of attenuated replicative semliki forest virus in human melanoma xenografts in severe combined immunodeficient mice

19 August 2017

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Immunization against MUC18/MCAM, a novel antigen that drives melanoma invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Alphavirus replicon particles containing the gene for HER2/neu inhibit breast cancer growth and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

VRP immunotherapy targeting neu: treatment efficacy and evidence for immunoediting in a stringent rat mammary tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Induction of human papilloma virus E6/E7-specific cytotoxic T-lymphocyte activity in immune-tolerant, E6/E7-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Antitumor efficacy of Venezuelan equine encephalitis virus replicon particles encoding mutated HPV16 E6 and E7 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Targeting human glioblastoma cells: comparison of nine viruses with oncolytic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Sindbis virus replicon particles encoding calreticulin linked to a tumor antigen generate long-term tumor-specific immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Eradication of established HPV16-transformed tumours after immunisation with recombinant Semliki Forest virus expressing a fusion protein of E6 and E7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Alphavirus vectors as tools in cancer gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Alphaviruses and their derived vectors as anti-tumor agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Potential of alphavirus vectors in the treatment of advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Semliki Forest virus vectors expressing transforming growth factor beta inhibit experimental autoimmune encephalomyelitis in Balb/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Effect of intranasal administration of Semliki Forest virus recombinant particles expressing reporter and cytokine genes on the progression of experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Marburg virus vaccines based upon alphavirus replicons protect guinea pigs and nonhuman primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Influenza virus (A/HK/156/97) hemagglutinin expressed by an alphavirus replicon system protects chickens against lethal infection with Hong Kong-origin H5N1 viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Human immunodeficiency virus type 1 Gag-specific vaginal immunity and protection after local immunizations with sindbis virus-based replicon particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

An alphavirus replicon particle chimera derived from venezuelan equine encephalitis and sindbis viruses is a potent gene-based vaccine delivery vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Alphavirus vectors for vaccine production and gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Recombinant alphaviruses as vectors for anti-tumour and anti-microbial immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Immunization with recombinant Semliki Forest virus induces protection against influenza challenge in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Self-replicative RNA vaccines elicit protection against influenza A virus, respiratory syncytial virus, and a tickborne encephalitis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Recombinant Semliki Forest virus particles encoding the prME or NS1 proteins of louping ill virus protect mice from lethal challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

A comparative study on the immunotherapeutic efficacy of recombinant Semliki Forest virus and adenovirus vector systems in a murine model for cervical cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Recombinant Semliki Forest virus particles expressing louping ill virus antigens induce a better protective response than plasmid-based DNA vaccines or an inactivated whole particle vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Semliki Forest virus-based vaccines: persistence, distribution and pathological analysis in two animal systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

A recombinant Semliki Forest virus particle vaccine encoding the prME and NS1 proteins of louping ill virus is effective in a sheep challenge model

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Oncolytic viruses in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Semiliki forest virus vector carrying the bovine viral diarrhea virus NS3 (p80) cDNA induced immune responses in mice and expressed BVDV protein in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Cell death mechanisms in the olfactory bulb of rats infected intranasally with Semliki forest virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

CNS gene therapy applications of the Semliki Forest virus 1 vector are limited by neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Characterization of immune responses elicited in macaques immunized sequentially with chimeric VEE/SIN alphavirus replicon particles expressing SIVGag and/or HIVEnv and with recombinant HIVgp140Env protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Vaccination of macaques with SIV immunogens delivered by Venezuelan equine encephalitis virus replicon particle vectors followed by a mucosal challenge with SIVsmE660.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Enhanced simian immunodeficiency virus-specific immune responses in macaques induced by priming with recombinant Semliki Forest virus and boosting with modified vaccinia virus Ankara.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Vaccination with recombinant alphavirus or immune-stimulating complex antigen against respiratory syncytial virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Biochemical and immunogenic characterization of soluble human immunodeficiency virus type 1 envelope glycoprotein trimers expressed by semliki forest virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Expression of the two major envelope proteins of equine arteritis virus as a heterodimer is necessary for induction of neutralizing antibodies in mice immunized with recombinant Venezuelan equine encephalitis virus replicon particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Increased human immunodeficiency virus type 1 Env expression and antibody induction using an enhanced alphavirus vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Alphavirus replicon particles expressing the two major envelope proteins of equine arteritis virus induce high level protection against challenge with virulent virus in vaccinated horses

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Efficient expansion of HIV-1-specific T cell responses by homologous immunization with recombinant Semliki Forest virus particles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Individual and bivalent vaccines based on alphavirus replicons protect guinea pigs against infection with Lassa and Ebola viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Construction and immunogenicity in a prime-boost regimen of a Semliki Forest virus-vectored experimental HIV clade A vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Recombinant RNA replicons derived from attenuated Venezuelan equine encephalitis virus protect guinea pigs and mice from Ebola hemorrhagic fever virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Induction of primary virus-cross-reactive human immunodeficiency virus type 1-neutralizing antibodies in small animals by using an alphavirus-derived in vivo expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Comparison of the protective efficacy of naked DNA, DNA-based Sindbis replicon, and packaged Sindbis replicon vectors expressing Hantavirus structural genes in hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

DNA-based and alphavirus-vectored immunisation with prM and E proteins elicits long-lived and protective immunity against the flavivirus, Murray Valley encephalitis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Double-subgenomic Sindbis virus recombinants expressing immunogenic proteins of Japanese encephalitis virus induce significant protection in mice against lethal JEV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

The preclinical testing of a formaldehyde inactivated Ross River virus vaccine designed for use in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Vaccination with a Sindbis virus-based DNA vaccine expressing antigen 85B induces protective immunity against Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

An RNA vaccine based on recombinant Semliki Forest virus particles expressing the Cu,Zn superoxide dismutase protein of Brucella abortus induces protective immunity in BALB/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Multiagent vaccines vectored by Venezuelan equine encephalitis virus replicon elicits immune responses to Marburg virus and protection against anthrax and botulinum neurotoxin in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Immune protection against staphylococcal enterotoxin-induced toxic shock by vaccination with a Venezuelan equine encephalitis virus replicon

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Novel Semliki Forest virus vectors with reduced cytotoxicity and temperature sensitivity for long-term enhancement of transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Development of a new noncytopathic Semliki Forest virus vector providing high expression levels and stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Deletions in the hypervariable domain of the nsP3 gene attenuate Semliki Forest virus virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

The use of a double subgenomic Sindbis virus expression system to study mosquito gene function: effects of antisense nucleotide number and duration of viral infection on gene silencing efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Increased Immunogenicity of a DNA-Launched Venezuelan Equine Encephalitis Virus-Based Replicon DNA Vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Enhancing immune responses using suicidal DNA vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Development and preclinical evaluation of an alphavirus replicon vaccine for influenza

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Inhibition of angiogenesis by a Semliki Forest virus vector expressing VEGFR-2 reduces tumour growth and metastasis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Infection, Interaction and the Expression of Virulence by Defined Strains of Semliki Forest Virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Semliki forest virus vectors engineered to express higher IL-12 levels induce efficient elimination of murine colon adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

The molecular pathogenesis of Semliki Forest virus: a model virus made useful?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Regression of mouse tumours and inhibition of metastases following administration of a Semliki Forest virus vector with enhanced expression of IL-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Treatment of rapidly growing K-BALB and CT26 mouse tumours using Semliki Forest virus and its derived vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Induction of apoptosis in BCL-2-expressing rat prostate cancer cells using the Semliki Forest virus vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Inhibition of human lung carcinoma cell growth by apoptosis induction using Semliki Forest virus recombinant particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Biodistribution and tumor infectivity of semliki forest virus vectors in mice: effects of re-administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Modulation of disease, T cell responses, and measles virus clearance in monkeys vaccinated with H-encoding alphavirus replicon particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Semliki Forest virus vectors expressing the H and HN genes of measles and mumps viruses reduce immunity induced by the envelope protein genes of rubella virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Cellular and humoral immune responses to alphavirus replicon vaccines expressing cytomegalovirus pp65, IE1, and gB proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Vaccination with Venezuelan equine encephalitis replicons encoding cowpox virus structural proteins protects mice from intranasal cowpox virus challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

A Semliki Forest virus replicon vectored DNA vaccine expressing the E2 glycoprotein of classical swine fever virus protects pigs from lethal challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Prime-boost immunization using DNA vaccine and recombinant Orf virus protects pigs against Pseudorabies virus (Herpes suid 1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Evaluation of FIV protein-expressing VEE-replicon vaccine vectors in cats

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Systemic, mucosal, and heterotypic immune induction in mice inoculated with Venezuelan equine encephalitis replicons expressing Norwalk virus-like particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Alphavirus replicon particles encoding the fusion or attachment glycoproteins of respiratory syncytial virus elicit protective immune responses in BALB/c mice and functional serum antibodies in rhesus macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Systemic tumor targeting and killing by Sindbis viral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Using sindbis viral vectors for specific detection and suppression of advanced ovarian cancer in animal models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Identification of amino acids of Sindbis virus E2 protein involved in targeting tumor metastases in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Restricted tissue tropism and acquired resistance to Sindbis viral vector expression in the absence of innate and adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

A novel alphavirus vaccine encoding prostate-specific membrane antigen elicits potent cellular and humoral immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

In vivo effects of vaccination with six-transmembrane epithelial antigen of the prostate: a candidate antigen for treating prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Evaluation of cancer virotherapy with attenuated replicative Semliki forest virus in different rodent tumor models

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Gene therapy for malignant glioma using Sindbis vectors expressing a fusogenic membrane glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Sindbis viruses and other alphaviruses as cause of human arthritic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

Semliki Forest Virus: Cause of a Fatal Case of Human Encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

A new generation of animal cell expression vectors based on the Semliki Forest virus replicon

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

The carboxyl-terminal 120-residue polypeptide of infectious bronchitis virus nucleocapsid induces cytotoxic T lymphocytes and protects chickens from acute infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

Immunogene therapy of recurrent glioblastoma multiforme with a liposomally encapsulated replication-incompetent Semliki forest virus vector carrying the human interleukin-12 gene--a phase I/II clinical protocol.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

A novel neurotropic expression vector based on the avirulent A7(74) strain of Semliki Forest virus

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

Two-helper RNA system for production of recombinant Semliki forest virus particles.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

DNA immunization against herpes simplex virus: enhanced efficacy using a Sindbis virus-based vector

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

Heterologous prime-boost strategy to immunize very young infants against measles: pre-clinical studies in rhesus macaques

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

Gene therapy progress and prospects cancer: oncolytic viruses.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

An outbreak of human Semliki Forest virus infections in Central African Republic

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

Semliki Forest virus A7(74) transduces hippocampal neurons and glial cells in a temperature-dependent dual manner

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

Recombinant Sindbis viruses expressing a cytotoxic T-lymphocyte epitope of a malaria parasite or of influenza virus elicit protection against the corresponding pathogen in mice

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000859

7 January 2021

10.1017/S1462399408000859

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

19000329