Arsenic trioxide mechanisms of action--looking beyond acute promyelocytic leukemia (Q37307720)

19 August 2017

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title

Arsenic trioxide mechanisms of action--looking beyond acute promyelocytic leukemia (English)

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19 August 2017

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Dennis A Carney

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19 August 2017

1 October 2008

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19 August 2017

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19 August 2017

49

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19 August 2017

1846-1851

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19 August 2017

10

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Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells

19 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Opportunities for Trisenox (arsenic trioxide) in the treatment of myelodysplastic syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Arsenic trioxide is a potent inhibitor of the interaction of SMRT corepressor with Its transcription factor partners, including the PML-retinoic acid receptor alpha oncoprotein found in human acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl-positive cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

21 January 2018

Apoptosis and leukaemia.

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Apoptosis in Burkitt lymphoma cells is prevented by promotion of cysteine uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Redox regulation of the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Mitochondrial implication in accidental and programmed cell death: apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Effects of arsenic trioxide (As2O3) on leukemic cells from patients with non-M3 acute myelogenous leukemia: studies of cytotoxicity, apoptosis and the pattern of resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: activation of caspases and down-regulation of Bcl-2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Effect of arsenic trioxide on viability, proliferation, and apoptosis in human megakaryocytic leukemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Arsenic trioxide inhibits growth of human T-cell leukaemia virus type I infected T-cell lines more effectively than retinoic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

ROS stress in cancer cells and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Redox signaling and the emerging therapeutic potential of thiol antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Redox regulation of cellular activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Role of NADPH oxidase in arsenic-induced reactive oxygen species formation and cytotoxicity in myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Arsenic trioxide: mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Involvement of CD95-independent caspase 8 activation in arsenic trioxide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Emodin enhances arsenic trioxide-induced apoptosis via generation of reactive oxygen species and inhibition of survival signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Role of Jun and Jun kinase in resistance of cancer cells to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Reactive oxygen species and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Cellular stress response and apoptosis in cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Nuclear factor-kappaB modulation as a therapeutic approach in hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Inhibition of NF-kappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Arsenic trioxide induces G2/M growth arrest and apoptosis after caspase-3 activation and bcl-2 phosphorylation in promonocytic U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

Catalase activity and arsenic sensitivity in acute leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802464745

10.1080/10428190802464745

21 January 2018

Identifiers

DOI

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19 August 2017

1 reference

PubMed ID

18949607