Tau mutations in neurodegenerative diseases (Q37307240)

19 August 2017

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title

Tau mutations in neurodegenerative diseases (English)

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19 August 2017

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Michael S Wolfe

1

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PubMed ID

18948254

19 August 2017

language of work or name

English

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publication date

22 October 2008

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Journal of Biological Chemistry

19 August 2017

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19 August 2017

284

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19 August 2017

6021-6025

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19 August 2017

10

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A century of Alzheimer's disease

19 August 2017

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

Neurodegenerative tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Tau is a candidate gene for chromosome 17 frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

A protein factor essential for microtubule assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Cytoskeletal Dynamics and Transport in Growth Cone Motility and Axon Guidance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Microtubule-dependent transport in neurons: steps towards an understanding of regulation, function and dysfunction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

Differential regulation of dynein and kinesin motor proteins by tau

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

Tau phosphorylation in neuronal cell function and dysfunction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

The distribution of tau in the mammalian central nervous system

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

The microtubule binding domain of tau protein.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

Tau protein binds to microtubules through a flexible array of distributed weak sites

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

Interaction of tau protein with the dynactin complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Structure and novel exons of the human tau gene

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Mutations causing neurodegenerative tauopathies

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

An English kindred with a novel recessive tauopathy and respiratory failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Mutations in the tau gene that cause an increase in three repeat tau and frontotemporal dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

5' splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Aberrant splicing of tau pre-mRNA caused by intronic mutations associated with the inherited dementia frontotemporal dementia with parkinsonism linked to chromosome 17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Mutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Frontotemporal dementia with Pick-type histology associated with Q336R mutation in the tau gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Accelerated filament formation from tau protein with specific FTDP-17 missense mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

A novel tau mutation in exon 9 (1260V) causes a four-repeat tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Tau assembly in inducible transfectants expressing wild-type or FTDP-17 tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Promotion of hyperphosphorylation by frontotemporal dementia tau mutations

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.R800013200

Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Tau suppression in a neurodegenerative mouse model improves memory function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Untangling the tau gene association with neurodegenerative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

Relevance of transgenic mouse models to human Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800013200

21 January 2018

Identifiers

DOI

10.1074/JBC.R800013200

1 reference

19 August 2017

1 reference

PubMed ID

18948254