Nur77 exacerbates PC12 cellular injury in vitro by aggravating mitochondrial impairment and endoplasmic reticulum stress (Q37294245)

19 August 2017

Nur77 exacerbates PC12 cellular injury in vitro by aggravating mitochondrial impairment and endoplasmic reticulum stress (English)

1 reference

19 August 2017

endoplasmic reticulum

0 references

1 reference

Huimin Gao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Zhaoyu Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Yongmei Fu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Xiaoyan Yang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Ruihui Weng

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Rui Wang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Jianjun Lu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Mengqiu Pan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Chris McElroy

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Beisha Tang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Qing Wang

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

0 references

publication date

29 September 2016

1 reference

19 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

34403

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

1 June 2020

copyright license

start time

29 September 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/srep34403

0 references

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6-Mercaptopurine attenuates tumor necrosis factor-α production in microglia through Nur77-mediated transrepression and PI3K/Akt/mTOR signaling-mediated translational regulation

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6 September 2017

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6 September 2017

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Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

6 September 2017

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TR3 is preferentially expressed by bulge epithelial stem cells in human hair follicles.

6 September 2017

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Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.

6 September 2017

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Dopamine Receptors and Neurodegeneration

6 September 2017

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Relevance of chronic stress and the two faces of microglia in Parkinson's disease

6 September 2017

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Farnesol activates the intrinsic pathway of apoptosis and the ATF4-ATF3-CHOP cascade of ER stress in human T lymphoblastic leukemia Molt4 cells.

6 September 2017

1 reference

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Mahogunin Ring Finger-1 (MGRN1), a Multifaceted Ubiquitin Ligase: Recent Unraveling of Neurobiological Mechanisms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

PINK1- and PARK2-mediated local mitophagy in distal neuronal axons

6 September 2017

1 reference

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ER stress and unfolded protein response in amyotrophic lateral sclerosis-a controversial role of protein disulphide isomerase

6 September 2017

1 reference

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Compensatory Motor Neuron Response to Chromatolysis in the Murine hSOD1(G93A) Model of Amyotrophic Lateral Sclerosis

6 September 2017

1 reference

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Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagy

6 September 2017

1 reference

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The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis.

6 September 2017

1 reference

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NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity

6 September 2017

1 reference

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Ubiquitin is phosphorylated by PINK1 to activate parkin

6 September 2017

1 reference

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Acetylshikonin induces apoptosis of hepatitis B virus X protein-expressing human hepatocellular carcinoma cells via endoplasmic reticulum stress

6 September 2017

1 reference

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Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway

6 September 2017

1 reference

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Defective quality control mechanisms and accumulation of damaged mitochondria link Gaucher and Parkinson diseases

6 September 2017

1 reference

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Integrating pathways of Parkinson's disease in a molecular interaction map.

6 September 2017

1 reference

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After the banquet: mitochondrial biogenesis, mitophagy, and cell survival

6 September 2017

1 reference

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Making the brain glow: in vivo bioluminescence imaging to study neurodegeneration

6 September 2017

1 reference

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Loss of prohibitin membrane scaffolds impairs mitochondrial architecture and leads to tau hyperphosphorylation and neurodegeneration

6 September 2017

1 reference

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ER stress inhibits neuronal death by promoting autophagy

6 September 2017

1 reference

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Molecular pathways: the role of NR4A orphan nuclear receptors in cancer.

6 September 2017

1 reference

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Macroautophagy is regulated by the UPR-mediator CHOP and accentuates the phenotype of SBMA mice

6 September 2017

1 reference

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Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis

6 September 2017

1 reference

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Regulation of PINK1-Parkin-mediated mitophagy.

6 September 2017

1 reference

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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

6 September 2017

1 reference

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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

6 September 2017

1 reference

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During negative selection, Nur77 family proteins translocate to mitochondria where they associate with Bcl-2 and expose its proapoptotic BH3 domain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Nur77 and retinoid X receptors: crucial factors in dopamine-related neuroadaptation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Nur77 gene knockout alters dopamine neuron biochemical activity and dopamine turnover

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

The NR4A subgroup: immediate early response genes with pleiotropic physiological roles

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Mutations in NR4A2 associated with familial Parkinson disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Hormesis: protecting neurons against cellular stress in Parkinson disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Involvement of induction and mitochondrial targeting of orphan nuclear receptor Nur77 in 6-OHDA-induced SH-SY5Y cell death

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Cytosporone B is an agonist for nuclear orphan receptor Nur77.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Involvement of TR3/Nur77 translocation to the endoplasmic reticulum in ER stress-induced apoptosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

CHIP, a carboxy terminus HSP-70 interacting protein, prevents cell death induced by endoplasmic reticulum stress in the central nervous system.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Contra-directional Coupling of Nur77 and Nurr1 in Neurodegeneration: A Novel Mechanism for Memantine-Induced Anti-inflammation and Anti-mitochondrial Impairment.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Nur77 Was Essential for Neurite Outgrowth and Involved in Schwann Cell Differentiation After Sciatic Nerve Injury.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Inhibition of neuroinflammation and mitochondrial dysfunctions by carbenoxolone in the rotenone model of Parkinson's disease.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Autophagy contributes to leaf starch degradation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Simvastatin induces neuroprotection in 6-OHDA-lesioned PC12 via the PI3K/AKT/caspase 3 pathway and anti-inflammatory responses

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

PINK1-parkin-dependent mitophagy involves ubiquitination of mitofusins 1 and 2: Implications for Parkinson disease pathogenesis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041156

Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27679973

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cancer therapy: Altering mitochondrial properties

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27679973

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential regulation of the transcriptional activity of the orphan nuclear receptor NGFI-B by membrane depolarization and nerve growth factor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27679973

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP34403

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27679973%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference