Pharmacokinetics of rectal drug administration, Part II. Clinical applications of peripherally acting drugs, and conclusions (Q37290777)

19 August 2017

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title

Pharmacokinetics of rectal drug administration, Part II. Clinical applications of peripherally acting drugs, and conclusions (English)

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19 August 2017

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van Hoogdalem EJ

1

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19 August 2017

de Boer AG

series ordinal

2

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19 August 2017

Breimer DD

series ordinal

3

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19 August 2017

1 August 1991

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Clinical Pharmacokinetics

19 August 2017

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19 August 2017

21

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19 August 2017

2

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19 August 2017

110-128

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https://scigraph.springernature.com/pub.10.2165/00003088-199121020-00003

19 August 2017

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Chloroquine absorption in children from polyethylene glycol base suppositories

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Rectal administration of propylthiouracil in the treatment of Graves' disease

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Plasma profiles following single, oral, and rectal doses of phenylbutazone in healthy volunteers

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Absolute intramuscular, oral, and rectal bioavailability of alizapride

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Premedication with oral and rectal diazepam

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Comparison of bioavailability in man of tamoxifen after oral and rectal administration

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Zero-order rectal delivery of theophylline in man with an osmotic system

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Pharmacokinetics of ergotamine in healthy volunteers following oral and rectal dosing

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Rectal administration of sodium valproate in children

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Low bioavailability of ergotamine tartrate after oral and rectal administration in migraine sufferers

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The pharmacokinetics of oxprenolol following oral and rectal dosing--a comparison of delivery systems and routes of administration

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Rate-controlled rectal absorption enhancement of cefoxitin by co-administration of sodium salicylate or sodium octanoate in healthy volunteers

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Relative bioavailability of rectally administered carbamazepine suspension in humans.

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Anorectal ergotism: another cause of solitary rectal ulcers

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Iatrogenic rectal stenosis caused by Veganine suppositories

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Absorption of enprofylline from the gastrointestinal tract in healthy subjects

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Rectal drug administration: clinical pharmacokinetic considerations

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Absolute bioavailability of paracetamol after oral or rectal administration in healthy volunteers.

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Rectal diclofenac compared with pethidine injection in acute renal colic

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12 December 2020

The morphine hydrogel suppository. A new sustained release rectal preparation

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Absorption of theophylline administered via colostomy

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Bioavailability of indomethacin after intramuscular injection and rectal administration of solution and suppositories

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12 December 2020

Absorption and bioavailability of oral erythromycin

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12 December 2020

Influence of cimetidine on steady state concentration and metabolite formation from antipyrine infused with a rectal osmotic mini pump

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12 December 2020

Plasma concentrations following single doses of morphine sulfate in oral solution and rectal suppository

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12 December 2020

Preliminary study on the absorption profile after rectal and oral administration of methadone in human volunteers

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12 December 2020

Pharmacokinetics of flunitrazepam after single rectal administration in children.

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12 December 2020

Rectal absorption enhancement of des-enkephalin-gamma-endorphin (DE gamma E) by medium-chain glycerides and EDTA in conscious rats

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12 December 2020

Plasma-diazepam in infants after rectal administration in solution and by suppository.

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12 December 2020

Absolute bioavailability of hydromorphone after peroral and rectal administration in humans: saliva/plasma ratio and clinical effects

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12 December 2020

Absorption kinetics of rectally and orally administered ibuprofen

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12 December 2020

Rectal infusion of the model drug antipyrine with an osmotic delivery system

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12 December 2020

Pharmacokinetics of hydromorphone after intravenous, peroral and rectal administration to human subjects

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12 December 2020

Rectal bioavailability of bacampicillin hydrochloride in man as determined by reversed-phase liquid chromatography.

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12 December 2020

Topical administration of 5-aminosalicylic acid enemas in patients with ulcerative colitis. Studies on rectal absorption and excretion

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12 December 2020

Penetration of clofoctol into human lung.

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The pharmacokinetic profile of naproxen suppository in man

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Pharmacokinetics of i.v. and rectal methohexitone in children.

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[Bioavailability of oral and rectal indomethacin]

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The bioavailability of rectally administered morphine

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Relative Bioavailability of Rectally Administered Phenobarbital Sodium Parenteral Solution

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Bioavailability of rectally administered carbamazepine mixture

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12 December 2020

A clinical trial of single dose rectal and oral administration of diazepam for the prevention of serial seizures in adult epileptic patients

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Rectal administration of morphine hydrogel: absorption and bioavailability in women

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Use of adjuvants for enhancement of rectal absorption of cefoxitin in humans

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Rectal absorption of propylthiouracil

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12 December 2020

Rectal and intravenous propranolol infusion to steady state: kinetics and beta-receptor blockade

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12 December 2020

Methohexital plasma concentrations in children following rectal administration

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12 December 2020

Pharmacokinetics of midazolam and alpha-hydroxy-midazolam following rectal and intravenous administration

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12 December 2020

Simultaneous determination of midazolam and its three hydroxy metabolites in human plasma by electron-capture gas chromatography without derivatization

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12 December 2020

Bioavailability of diazepam after intravenous, oral and rectal administration in adult epileptic patients

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12 December 2020

Drug absorption by sublingual and rectal routes

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12 December 2020

Intestinal drug absorption enhancement: an overview

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12 December 2020

Rate of increase in the plasma concentration of nifedipine as a major determinant of its hemodynamic effects in humans

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12 December 2020

Pharmacokinetics and clinical efficacy of intrarectal solution of acetaminophen

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12 December 2020

Effectiveness of insulin suppositories in diabetic patients

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12 December 2020

Rectal administration of metronidazole in severely ill patients.

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12 December 2020

Rectal stenosis due to long-term therapy with ergotamine

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12 December 2020

[Solitary lesions of the rectum caused by suppositories combining acetylsalicylic acid and paracetamol]

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12 December 2020

Bioavailability of sodium valproate suppositories during repeated administration at steady state in epileptic children.

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12 December 2020

Rectal absorption of metronidazole from polyethylene glycol suppositories

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12 December 2020

Absorption of valproic acid suppositories in human volunteers

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12 December 2020

Rectal diazepam in the treatment of absence status: a pharmacodynamic study

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12 December 2020

Rectal versus oral absorption of codeine phosphate in man

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12 December 2020

Serum concentration of clonazepam after rectal administration

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12 December 2020

Pharmacokinetics of two per cent rectal methohexitone in children

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12 December 2020

Rectal administration of medroxyprogesterone acetate in cancer patients: a pharmacokinetic study

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12 December 2020

5-Aminosalicylic acid enema in the treatment of distal ulcerative colitis, proctosigmoiditis, and proctitis

1 reference

12 December 2020

Clinical pharmacokinetic comparison of two indometacin containing suppositories with different vehicula

1 reference

12 December 2020

Absorption rate and bioavailability of valproic acid and its sodium from rectal dosage forms

1 reference

12 December 2020

The effect of rectal pH values on the absorption of methohexital

1 reference

12 December 2020

Effectiveness and absorption of rectal hydrocortisone acetate foam in nonspecific proctocolitis

1 reference

12 December 2020

Nifedipine gastrointestinal therapeutic system in stable angina pectoris. Results of a multicenter open-label crossover comparison with standard nifedipine

1 reference

12 December 2020

Plasma concentrations of atropine after rectal administration.

1 reference

12 December 2020

Rectal administration of nifedipine: haemodynamic effects and pharmacokinetics in hypertensives

1 reference

12 December 2020

Characteristics of drug absorption via the rectal route.

1 reference

12 December 2020

Quantitative distribution of radiolabeled 5-aminosalicylic acid enemas in patients with left-sided ulcerative colitis

1 reference

12 December 2020

Disposition of radiolabelled suppositories in humans

1 reference

12 December 2020

Drastic improvement in the rectal absorption profile of morphine in man

1 reference

12 December 2020

Absorption of diazepam from the rectum and its effect on interictal spikes in the EEG.

1 reference

12 December 2020

Comparison of pharmacodynamic effects and plasma levels of oral and rectal ergotamine

1 reference

12 December 2020

Absolute bioavailability of metoclopramide given orally or by enema in patients with normal liver function or with cirrhosis of the liver

1 reference

12 December 2020

Absorption of 5-aminosalicylic acid from colon and rectum

1 reference

12 December 2020

Rectal methohexital for induction of anesthesia in children with and without rectal aspiration after sleep: a pharmacokinetic and pharmacodynamic study.

1 reference

12 December 2020

[The relative bioavailability of paracetamol following administration of solid and liquid oral preparations and rectal dosage forms]

1 reference

12 December 2020

Topical corticosteroids in inflammatory bowel disease

1 reference

12 December 2020

1 reference

12 December 2020

Rectal induction of anaesthesia in children with methohexitone. Patient acceptability and clinical pharmacokinetics.

1 reference

12 December 2020

Intestinal absorption of proteins and macromolecules and the immunological response

1 reference

12 December 2020

Systemic absorption from prednisolone rectal foam in ulcerative colitis

1 reference

12 December 2020

Biopharmaceutical investigation of rectal suppositories. Part 2(1): Pharmaceutical and biological availability of phenobarbital and phenobarbital-sodium

1 reference

12 December 2020

Pharmacokinetics of oral and rectal flurbiprofen in children

1 reference

12 December 2020

Clinical pharmacokinetics of ergotamine in migraine and cluster headache

1 reference

12 December 2020

Absorption and excretion of azodisal sodium and its metabolites in man after rectal administration of a single 2-g dose

1 reference

12 December 2020

Pharmacokinetics and bioavailability of theophylline following enema and suppository administration in man.

1 reference

12 December 2020

Retrograde spread of mesalazine (5-aminosalicylic acid)-containing enema in patients with ulcerative colitis

1 reference

12 December 2020

Preoperative irradiation and 5-fluorouracil suppository for carcinoma of the rectum

1 reference

12 December 2020

Site specific rectal drug administration in man with an osmotic system: influence on "first-pass" elimination of lidocaine

1 reference

12 December 2020

Rectal aminophylline in the management of apnoea of prematurity

1 reference

12 December 2020

Retrograde spread of hydrocortisone containing foam given intrarectally in ulcerative colitis

1 reference

12 December 2020

The pharmacokinetics of rectal midazolam for premedication in children.

1 reference

12 December 2020

Rate-limiting barriers to intestinal drug absorption: a review

1 reference

12 December 2020

[Comparative studies on the bioavailability of paracetamol from suppositories]

1 reference

12 December 2020

Absorption and bioavailability of diclofenac after rectal administration of diclofenac-na gel preparation in rat and man

1 reference

12 December 2020

Nifedipine kinetics and dynamics during rectal infusion to steady state with an osmotic system

1 reference

12 December 2020

Plasma progesterone levels after using high dose suppositories. A preliminary report

1 reference

12 December 2020

Clinical evaluation of rectally administered ampicillin in acute otitis media

1 reference

12 December 2020

Topical effects of absorption enhancing agents on the rectal mucosa of rats in vivo

1 reference

12 December 2020

Proctitis following the prolonged use of dextropropoxyphene and paracetamol suppositories: the risk persists despite change of excipient

1 reference

12 December 2020

Rectal absorption of flecainide acetate

1 reference

12 December 2020

Diazepam in rectal solution as premedication in children, with special reference to serum concentrations

1 reference

12 December 2020

Rectally administered prednisolone--evidence for a predominantly local action

1 reference

12 December 2020

Prophylactic short course rectal metronidazole for cesarean section. A double-blind controlled trial of a simple low cost regimen

1 reference

12 December 2020

Clinical Pharmacokinetics of Metronidazole

1 reference

12 December 2020

Effect of isoxazolyl-penicillin on the rectal absorption of ampicillin in rabbits and humans

1 reference

12 December 2020

Correlation between antipyrine metabolite formation and theophylline metabolism in humans after simultaneous single-dose administration and at steady state

1 reference

12 December 2020

Colonic motility and enema spreading

1 reference

12 December 2020

Mesalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in chronic inflammatory bowel disease

1 reference

12 December 2020

Retrograde spread of therapeutic enemas in patients with inflammatory bowel disease

1 reference

12 December 2020

Prevention of postoperative anaerobic infections. Economic significance of metronidazole suppositories

1 reference

12 December 2020

Rectal absorption of a theophylline solution in asthma

1 reference

12 December 2020

Nifedipine gastrointestinal therapeutic system

1 reference

12 December 2020

Plasma concentrations and bioavailability of propranolol by oral, rectal, and intravenous administration in man

1 reference

12 December 2020

5-Aminosalicylic acid in serum and urine after administration by enema to patients with colitis

1 reference

12 December 2020

[Effect of the interaction between paracetamol and non-ionic surfactants on rectal absorption from suppositories]

1 reference

12 December 2020

Plasma concentrations of clonazepam after single rectal administration

1 reference

12 December 2020

Comparison of disappearance from blood and lymphatic delivery of human fibroblast interferon in rat by different administration routes.

1 reference

12 December 2020

Comparative pharmacokinetics of sulphasalazine and sulphapyridine after rectal and oral administration to patients with ulcerative colitis

1 reference

12 December 2020

Pharmacokinetics of rectal diazepam in the prevention of recurrent febrile convulsions.

1 reference

12 December 2020

Rectal administration of diazepam in solution in the acute treatment of convulsions in infants and children

1 reference

12 December 2020

Rectal administration of diazepam in solution. A clinical study on sedation in paediatric dentistry

1 reference

12 December 2020

Pharmacokinetics of two rectal dosage forms of ketoprofen in patients after anal surgery

1 reference

12 December 2020

Power analyses of moment analysis parameter in bioequivalence tests

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12 December 2020

Comparison of the bioavailability of oral, rectal and intramuscular promethazine

1 reference

12 December 2020

10.2165/00003088-199121020-00003

Identifiers

DOI

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Dimensions Publication ID

19 August 2017

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