Phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American Brain Tumor Consortium study (Q37286891)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514370%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American Brain Tumor Consortium study (English)

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4 January 2020

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17

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11

Patrick Wen

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9

Timothy F Cloughesy

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10

Larry Junck

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author name string

Vinay K Puduvalli

1

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W K Alfred Yung

2

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Kenneth R Hess

3

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John G Kuhn

4

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Morris D Groves

5

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Victor A Levin

6

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James Zwiebel

7

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Susan M Chang

8

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Frank Lieberman

12

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Charles A Conrad

13

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Mark R Gilbert

14

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Christina A Meyers

15

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Vivien Liu

16

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M Kelly Nicholas

18

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Michael Prados

19

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North American Brain Tumor Consortium

20

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language of work or name

English

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publication date

1 November 2004

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Journal of Clinical Oncology

4 January 2020

published in

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volume

22

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issue

21

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4 January 2020

page(s)

4282-4289

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Breast tissue accumulation of retinamides in a randomized short-term study of fenretinide

4 January 2020

cites work

1 reference

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Toward better early-phase brain tumor clinical trials: a reappraisal of current methods and proposals for future strategies.

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Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials

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A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival

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Fenretinide activates caspases and induces apoptosis in gliomas

6 September 2017

1 reference

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Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines

6 September 2017

1 reference

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Chemoprevention trial of contralateral breast cancer with fenretinide. Rationale, design, methodology, organization, data management, statistics and accrual.

6 September 2017

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Five-year administration of fenretinide: pharmacokinetics and effects on plasma retinol concentrations

6 September 2017

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Phase II trial of fenretinide [N-(4-hydroxyphenyl) retinamide] in myelodysplasia: possible retinoid-induced disease acceleration

6 September 2017

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Distribution of fenretinide in the mammary gland of breast cancer patients

6 September 2017

1 reference

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Vitamin A, differentiation and cancer

6 September 2017

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An analysis of dose-effect relationship in the radiotherapy of malignant gliomas

14 September 2017

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Retinoids inhibit human glioma cell proliferation and migration in primary cell cultures but not in established cell lines

14 September 2017

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Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials

28 September 2017

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Abnormal retinal function associated with fenretinide, a synthetic retinoid

28 September 2017

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Effects of meals and meal composition on the bioavailability of fenretinide

26 June 2018

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Phase I trial and pharmacokinetics of fenretinide in children with neuroblastoma.

26 June 2018

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Assessing symptom distress in cancer patients: the M.D. Anderson Symptom Inventory.

3 September 2018

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Pharmacokinetics of all-trans retinoic acid, 13-cis retinoic acid, and fenretinide in plasma and brain of Rat.

3 September 2018

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Treatment of recurrent malignant gliomas with high-dose 13-cis-retinoic acid.

3 September 2018

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Phase II chemoprevention trial of oral fenretinide in patients at risk for adenocarcinoma of the prostate.

3 September 2018

1 reference

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Visual and cutaneous toxicity which occurs during N-(4-hydroxyphenyl) retinamide therapy for psoriasis

3 September 2018

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12 December 2020

Plasma retinol level reduction by the synthetic retinoid fenretinide: a one year follow-up study of breast cancer patients

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12 December 2020

Ocular toxic effects of fenretinide

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12 December 2020

Phase IIa study of fenretinide in superficial bladder cancer, using DNA flow cytometry as an intermediate end point

1 reference

12 December 2020

Breast cancer chemoprevention: studies with 4-HPR alone and in combination with tamoxifen using circulating growth factors as potential surrogate endpoints

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12 December 2020

Effects of fenretinide (4-HPR) on dark adaptation

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12 December 2020

Induction of apoptosis by N-(4-hydroxyphenyl)retinamide and its association with reactive oxygen species, nuclear retinoic acid receptors, and apoptosis-related genes in human prostate carcinoma cells

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12 December 2020

Induction of apoptosis by N-(4-hydroxyphenyl)retinamide in glioma cells

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12 December 2020

Identifiers

DOI

10.1200/JCO.2004.09.096

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514370%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514370%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference