The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile (Q37282817)

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scientific article published on 30 September 2008

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English	The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile	scientific article published on 30 September 2008

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scholarly article

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The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile (English)

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neurodegeneration

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25 April 2019

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19 September 2019

28 September 2019

2 October 2019

18 October 2019

biomedical investigative technique

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19 September 2019

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28 September 2019

mechanism of action

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2 October 2019

hemic and immune systems

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18 October 2019

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11 October 2020

risk assessment

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17 October 2020

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13 November 2020

2

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Giulia Di Benedetto

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Renato Bernardini

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Daria Brambilla

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Mariagrazia Rita Scuderi

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Paolo Bosco

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Giuseppina Cantarella

5

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Laurence Lempereur

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Salvatore Pezzino

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30 September 2008

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13 November 2020

Nutrition Journal

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19 September 2019

28 September 2019

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copyright license

Creative Commons Attribution 2.0 Generic

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on focus list of Wikimedia project

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https://scigraph.springernature.com/pub.10.1186/1475-2891-7-29

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Micronutrients prevent cancer and delay aging

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Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial

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Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

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Vitamin E and immune functions

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

14 September 2017

beta-Carotene exacerbates DNA oxidative damage and modifies p53-related pathways of cell proliferation and apoptosis in cultured cells exposed to tobacco smoke condensate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

14 September 2017

Epstein-Barr virus-associated haemophagocytic lymphohistiocytosis in Wiskott-Aldrich syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

14 September 2017

Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

14 September 2017

Antioxidants inhibit mercuric chloride-induced early vasculitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

28 September 2017

A redox signaling mechanism for density-dependent inhibition of cell growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

28 September 2017

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

28 September 2017

Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

28 September 2017

Changes in sizes of cortical and lower motor neurons in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

28 September 2017

Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

26 June 2018

Oxidative stress induces age-dependent changes in lymphocyte protein synthesis and second messenger levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

26 June 2018

Increased protein oxidation in human substantia nigra pars compacta in comparison with basal ganglia and prefrontal cortex measured with an improved dinitrophenylhydrazine assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

26 June 2018

Role of metal-catalyzed oxidation reactions in the early pathogenesis of scleroderma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

26 June 2018

Scleroderma autoantigens are uniquely fragmented by metal-catalyzed oxidation reactions: implications for pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

26 June 2018

TRPV1 mediates cell death in rat synovial fibroblasts through calcium entry-dependent ROS production and mitochondrial depolarization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Intracellular oxidative activation in synovial fluid neutrophils from patients with rheumatoid arthritis but not from other arthritis patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Bilirubin: a natural inhibitor of vascular smooth muscle cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

The effect of vitamin E supplementation on antioxidant enzyme activities and lipid peroxidation levels in hemodialysis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Bilirubin and S-nitrosothiols interaction: evidence for a possible role of bilirubin as a scavenger of nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Heme oxygenase-1 is an antifibrogenic protein in human hepatic myofibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Fruits and vegetables are associated with lower lung cancer risk only in the placebo arm of the beta-carotene and retinol efficacy trial (CARET)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Carbon monoxide inhibits human airway smooth muscle cell proliferation via mitogen-activated protein kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Recovery mechanism of the antioxidant activity from carnosic acid quinone, an oxidized sage and rosemary antioxidant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzole-tocopherol Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Antioxidants as adjuvant therapy in rheumatoid disease. A preliminary study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Endogenous oxygen radicals modulate protein tyrosine phosphorylation and JNK-1 activation in lectin-stimulated thymocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Effect of Avemar and Avemar + vitamin C on tumor growth and metastasis in experimental animals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Induction of immune system mediators in the hippocampal formation in Alzheimer's and Parkinson's diseases: selective effects on specific interleukins and interleukin receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572622

3 September 2018

Long-term monitoring of insulin-like growth factor I in adult growth hormone deficiency: a critical appraisal.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2891-7-29

21 January 2018

Vitamin C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin E supplementation enhances immune response in the elderly

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible non-classic intracellular and molecular mechanisms of LDL cholesterol action contributing to the development and progression of atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen intermediates as mediators of programmed cell death in plants and animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide induces up-regulation of Fas in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of antioxidants in transmissible spongiform encephalopathies: a case report

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of metals in autoimmunity and the link to neuroendocrinology

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of proteolysis at the neutrophil-substrate interface by secretory leukoprotease inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Albumin-bound bilirubin interacts with nitric oxide by a redox mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated leukocytes oxidatively damage DNA, RNA, and the nucleotide pool through halide-dependent formation of hydroxyl radical

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AVEMAR (a new benzoquinone-containing natural product) administration interferes with the Th2 response in experimental SLE and promotes amelioration of the disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactions of beta-carotene with cigarette smoke oxidants. Identification of carotenoid oxidation products and evaluation of the prooxidant/antioxidant effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and iron homeostasis: mechanistic and health aspects

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1475-2891-7-29

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18826565%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18826565%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18826565%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

ResearchGate publication ID

0 references

Sitelinks

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