Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus (Q37281455)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601660%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

title

Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601660%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

0 references

1 reference

1 reference

1

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22 March 2020

Raymond Dingledine

7

1 reference

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22 March 2020

5

Richard M Ransohoff

1 reference

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22 March 2020

author name string

Jonas J Neher

2

1 reference

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22 March 2020

Andrea Bosch

3

1 reference

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22 March 2020

Wenyi Wang

4

1 reference

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22 March 2020

Richard J Miller

6

1 reference

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22 March 2020

language of work or name

English

0 references

publication date

6 September 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601660%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

22 March 2020

published in

1 reference

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22 March 2020

volume

113

1 reference

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22 March 2020

issue

38

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22 March 2020

page(s)

E5665-74

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601660%20AND%20SRC:MED&resulttype=core&format=json

Central nervous system myeloid cells as drug targets: current status and translational challenges

22 March 2020

cites work

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Immunity and inflammation in status epilepticus and its sequelae: possibilities for therapeutic application.

6 September 2017

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Inhibition of the prostaglandin EP2 receptor is neuroprotective and accelerates functional recovery in a rat model of organophosphorus induced status epilepticus

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus

6 September 2017

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Longitudinal assessment of blood-brain barrier leakage during epileptogenesis in rats. A quantitative MRI study

6 September 2017

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Identification of a unique TGF-β-dependent molecular and functional signature in microglia

6 September 2017

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Successful surgical treatment of an inflammatory lesion associated with new-onset refractory status epilepticus.

6 September 2017

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Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion

6 September 2017

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EP2 receptor signaling pathways regulate classical activation of microglia.

6 September 2017

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Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation

6 September 2017

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Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells

6 September 2017

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Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS.

6 September 2017

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Reduction in delayed mortality and subtle improvement in retrograde memory performance in pilocarpine-treated mice with conditional neuronal deletion of cyclooxygenase-2 gene

6 September 2017

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The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood

6 September 2017

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Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus

6 September 2017

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Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

6 September 2017

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Interleukin-1β biosynthesis inhibition reduces acute seizures and drug resistant chronic epileptic activity in mice

6 September 2017

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Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages.

6 September 2017

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The myeloid cells of the central nervous system parenchyma

6 September 2017

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Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice

6 September 2017

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Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging

6 September 2017

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Chemokine CCL2 and its receptor CCR2 are increased in the hippocampus following pilocarpine-induced status epilepticus

6 September 2017

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Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice

6 September 2017

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Visualization of chemokine receptor activation in transgenic mice reveals peripheral activation of CCR2 receptors in states of neuropathic pain

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Blood-brain barrier leakage may lead to progression of temporal lobe epilepsy

6 September 2017

1 reference

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TGF-beta receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis

6 September 2017

1 reference

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Control of microglial neurotoxicity by the fractalkine receptor

6 September 2017

1 reference

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The many roles of chemokines and chemokine receptors in inflammation

6 September 2017

1 reference

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Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

6 September 2017

1 reference

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Interleukin-1beta contributes to the generation of experimental febrile seizures

6 September 2017

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Blood monocytes consist of two principal subsets with distinct migratory properties

6 September 2017

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Interleukin-1 and neuronal injury: mechanisms, modification, and therapeutic potential

6 September 2017

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Characterization of neuronal death induced by focally evoked limbic seizures in the C57BL/6 mouse

6 September 2017

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Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2.

6 September 2017

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CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis

6 September 2017

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Bacterial lipopolysaccharide rapidly inhibits expression of C-C chemokine receptors in human monocytes

6 September 2017

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Microglia are less pro-inflammatory than myeloid infiltrates in the hippocampus of mice exposed to status epilepticus.

6 September 2017

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Resident microglia, rather than blood-derived macrophages, contribute to the earlier and more pronounced inflammatory reaction in the immature compared with the adult hippocampus after hypoxia-ischemia

14 September 2017

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CCR2 deficiency impairs macrophage infiltration and improves cognitive function after traumatic brain injury

28 September 2017

1 reference

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Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice

26 June 2018

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Highly specific neuron loss preserves lateral inhibitory circuits in the dentate gyrus of kainate-induced epileptic rats

26 June 2018

1 reference

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In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed.

26 June 2018

1 reference

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Increased population of oligodendroglia-like cells in pediatric intractable epilepsy.

3 September 2018

1 reference

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Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

3 September 2018

1 reference

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Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

Brain infiltration of leukocytes contributes to the pathophysiology of temporal lobe epilepsy.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

Characterization of monocyte chemoattractant protein-1 expression following a kainate model of status epilepticus

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.

3 September 2018

1 reference

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Mannose receptor expression specifically reveals perivascular macrophages in normal, injured, and diseased mouse brain

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

Innate immune reaction in response to seizures: implications for the neuropathology associated with epilepsy

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

Reciprocal changes of CD44 and GAP-43 expression in the dentate gyrus inner molecular layer after status epilepticus in mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

Stereological analysis of astrocyte and microglia in aging mouse hippocampus.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5035862

P2X7-dependent, but differentially regulated release of IL-6, CCL2, and TNF-α in cultured mouse microglia

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27601660

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27601660

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1604263113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601660%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601660%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference